Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes (original) (raw)

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Bioorganic & Medicinal Chemistry, 2006

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New Journal of Chemistry, 2010

Quantitative Assessment of mRNA Cap Analogues as Inhibitors of in Vitro Translation †

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Synthesis of Anti-Reverse Cap Analogs (ARCAs) and their Applications in mRNA Translation and Stability

2007

Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation

Marcin Ziemniak, Jacek Jemielity

Bioorganic & Medicinal Chemistry Letters, 2009

Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS

RNA, 2008

Novel "anti-reverse" cap analogs with superior translational properties

2003

Synthesis of the first double-functionalized dinucleotide mRNA cap analogue for its specific labeling

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Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect

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ACS Chemical Biology, 2021

Inhibition of eukaryotic translation by analogs of messenger RNA 5'-cap: chemical and biological consequences of 5'-phosphate modifications of 7-methylguanosine 5'-monophosphate

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Inhibition of eukaryotic translation by nucleoside 5'-monophosphate analogs of mRNA 5'-cap: changes in N7 substituent affect analog activity

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Biochemistry, 1989

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Cell cycle (Georgetown, Tex.), 2018

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Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation

Kate Dudek

European journal of medicinal chemistry, 2016

Weak binding affinity of human 4EHP for mRNA cap analogs

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RNA, 2007

Fluorescence and NMR studies of intramolecular stacking of mRNA cap-analogues

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Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1997

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Journal of Medicinal Chemistry, 2012

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2013