Activity of new NOP receptor ligands in a rat peripheral mononeuropathy model: Potentiation of morphine anti-allodynic activity by NOP receptor antagonists (original ) (raw )NOP receptor mediates anti-analgesia induced by agonist–antagonist opioids
Luiz Ferrari
Neuroscience, 2014
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Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
Taline Khroyan
Journal of Pharmacology and Experimental Therapeutics, 2011
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Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation
Sanzio Candeletti
CNS Drugs
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Activities of mixed NOP and μ‐opioid receptor ligands
Stephen Husbands
British journal of …, 2008
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Lack of the nociceptin receptor does not affect acute or chronic nociception in mice
Angelo Forlani
Peptides, 2002
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Anti-allodynic Effect of Nefopam and Morphine in a Rat Model of Neuropathic Pain
Elham Saghaei
Novelty in Biomedicine, 2013
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Mu-opioid receptors are not necessary for nortriptyline treatment of neuropathic allodynia
Yohann Bohren
European Journal of Pain, 2010
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Effects of Spinally Administered Bifunctional Nociceptin/Orphanin FQ Peptide Receptor/μ-Opioid Receptor Ligands in Mouse Models of Neuropathic and Inflammatory Pain
Stephen Husbands
Journal of Pharmacology and Experimental Therapeutics, 2013
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Effects of Spinally Administered Bifunctional Nociceptin/Orphanin FQ Peptide Receptor/ -Opioid Receptor Ligands in Mouse Models of Neuropathic and Inflammatory Pain
Stephen Husbands
Journal of Pharmacology and Experimental Therapeutics, 2013
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The NOP receptor involvement in both withdrawal- and CCk-8-induced contracture responses of guinea pig isolated ileum after acute activation of κ-opioid receptor
Paolo Tucci
Peptides, 2012
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Stimulation of peripheral nociceptor endings by low dose morphine and its signaling mechanism
Md Rashid
Neurochemistry International, 2002
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Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys
Samuel Obeng
European Journal of Pharmacology, 2018
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Development of nociceptin receptor (NOP) agonists and antagonists
Carlo Mustazza
Medicinal Research Reviews, 2011
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Peripheral antinociceptive effects of µ- and δ-opioid receptor agonists in NOS2 and NOS1 knockout mice during chronic inflammatory pain
Olga Pol
European Journal of Pharmacology, 2009
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Coexpression of - and -opioid receptors in nociceptive sensory neurons
zhengbin li , Y.-q. Zhong
Proceedings of the National Academy of Sciences, 2010
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Role of opioid receptors in the reduction of formalin-induced secondary allodynia and hyperalgesia in rats
Vinicio Granados-soto
European Journal of Pharmacology, 2009
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Nociceptor sensitization in pain pathogenesis
Michael Gold
Nature Medicine, 2010
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Antagonists of the κ -opioid receptor enhance allodynia in rats and mice after sciatic nerve ligation
Barbara Przewlocka
British Journal of Pharmacology, 2003
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Allodynia and hyperalgesia suppression by a novel analgesic in experimental neuropathic pain
Nicolas Bazan
Biochemical and Biophysical Research Communications, 2006
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Quantitative study of [Tyr10]nociceptin/orphanin FQ (1-11) at NOP receptors in rat periaqueductal gray and expressed NOP receptors in HEK293 cells
Cynthia Lee , Lih-chu Chiou
Life Sciences, 2012
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Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain
Simone Ronsisvalle
Life Sciences, 2009
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Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling
Olga Pol
Molecular Pain, 2011
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Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury
Srinivasa Raja
PAIN, 2008
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SR 16435 [1-(1-(Bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin-2-one], a Novel Mixed Nociceptin/Orphanin FQ/ -Opioid Receptor Partial Agonist: Analgesic and Rewarding Properties in Mice
Taline Khroyan
Journal of Pharmacology and Experimental Therapeutics, 2006
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Novel Mixed NOP/Opioid Receptor Peptide Agonists
VICTOR HOLANDA
Journal of Medicinal Chemistry, 2021
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Spinal and local peripheral antiallodynic activity of Ro64-6198 in neuropathic pain in the rat
Barbara Przewlocka , Ilona Obara
Pain, 2005
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Morphine peripheral analgesia depends on activation of the PI3K /AKT/nNOS/NO/KATP signaling pathway
Fernando Guilherme Moura
Proceedings of The National Academy of Sciences, 2010
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Antinociceptive and anti-allodynic effects of oral PL37, a complete inhibitor of enkephalin-catabolizing enzymes, in a rat model of peripheral neuropathic pain induced by vincristine
Taline Khroyan
European Journal of Pharmacology, 2008
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GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice
Mauro Quartaroli
European Journal of Pharmacology, 2001
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Quantitative study of [(pF)Phe4,Arg14,Lys15]nociceptin/orphanin FQ-NH2 (UFP-102) at NOP receptors in rat periaqueductal gray slices
Lih-chu Chiou
European Journal of Pharmacology, 2008
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Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level
Javier Garzón
British Journal of Pharmacology, 2012
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The Role of Nitric Oxide in the Local Antiallodynic and Antihyperalgesic Effects and Expression of Opioid and Cannabinoid2 Receptors during Neuropathic Pain in Mice
Jesus Campos
Journal of Pharmacology and Experimental Therapeutics, 2010
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