Activity of new NOP receptor ligands in a rat peripheral mononeuropathy model: Potentiation of morphine anti-allodynic activity by NOP receptor antagonists (original) (raw)

NOP receptor mediates anti-analgesia induced by agonist–antagonist opioids

Luiz Ferrari

Neuroscience, 2014

View PDFchevron_right

Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice

Taline Khroyan

Journal of Pharmacology and Experimental Therapeutics, 2011

View PDFchevron_right

Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation

Sanzio Candeletti

CNS Drugs

View PDFchevron_right

Activities of mixed NOP and μ‐opioid receptor ligands

Stephen Husbands

British journal of …, 2008

View PDFchevron_right

Lack of the nociceptin receptor does not affect acute or chronic nociception in mice

Angelo Forlani

Peptides, 2002

View PDFchevron_right

Anti-allodynic Effect of Nefopam and Morphine in a Rat Model of Neuropathic Pain

Elham Saghaei

Novelty in Biomedicine, 2013

View PDFchevron_right

Mu-opioid receptors are not necessary for nortriptyline treatment of neuropathic allodynia

Yohann Bohren

European Journal of Pain, 2010

View PDFchevron_right

Effects of Spinally Administered Bifunctional Nociceptin/Orphanin FQ Peptide Receptor/μ-Opioid Receptor Ligands in Mouse Models of Neuropathic and Inflammatory Pain

Stephen Husbands

Journal of Pharmacology and Experimental Therapeutics, 2013

View PDFchevron_right

Effects of Spinally Administered Bifunctional Nociceptin/Orphanin FQ Peptide Receptor/ -Opioid Receptor Ligands in Mouse Models of Neuropathic and Inflammatory Pain

Stephen Husbands

Journal of Pharmacology and Experimental Therapeutics, 2013

View PDFchevron_right

The NOP receptor involvement in both withdrawal- and CCk-8-induced contracture responses of guinea pig isolated ileum after acute activation of κ-opioid receptor

Paolo Tucci

Peptides, 2012

View PDFchevron_right

Stimulation of peripheral nociceptor endings by low dose morphine and its signaling mechanism

Md Rashid

Neurochemistry International, 2002

View PDFchevron_right

Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys

Samuel Obeng

European Journal of Pharmacology, 2018

View PDFchevron_right

Development of nociceptin receptor (NOP) agonists and antagonists

Carlo Mustazza

Medicinal Research Reviews, 2011

View PDFchevron_right

Peripheral antinociceptive effects of µ- and δ-opioid receptor agonists in NOS2 and NOS1 knockout mice during chronic inflammatory pain

Olga Pol

European Journal of Pharmacology, 2009

View PDFchevron_right

Coexpression of - and -opioid receptors in nociceptive sensory neurons

zhengbin li, Y.-q. Zhong

Proceedings of the National Academy of Sciences, 2010

View PDFchevron_right

Role of opioid receptors in the reduction of formalin-induced secondary allodynia and hyperalgesia in rats

Vinicio Granados-soto

European Journal of Pharmacology, 2009

View PDFchevron_right

Nociceptor sensitization in pain pathogenesis

Michael Gold

Nature Medicine, 2010

View PDFchevron_right

Antagonists of the κ -opioid receptor enhance allodynia in rats and mice after sciatic nerve ligation

Barbara Przewlocka

British Journal of Pharmacology, 2003

View PDFchevron_right

Allodynia and hyperalgesia suppression by a novel analgesic in experimental neuropathic pain

Nicolas Bazan

Biochemical and Biophysical Research Communications, 2006

View PDFchevron_right

Quantitative study of [Tyr10]nociceptin/orphanin FQ (1-11) at NOP receptors in rat periaqueductal gray and expressed NOP receptors in HEK293 cells

Cynthia Lee, Lih-chu Chiou

Life Sciences, 2012

View PDFchevron_right

Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain

Simone Ronsisvalle

Life Sciences, 2009

View PDFchevron_right

Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling

Olga Pol

Molecular Pain, 2011

View PDFchevron_right

Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury

Srinivasa Raja

PAIN, 2008

View PDFchevron_right

SR 16435 [1-(1-(Bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin-2-one], a Novel Mixed Nociceptin/Orphanin FQ/ -Opioid Receptor Partial Agonist: Analgesic and Rewarding Properties in Mice

Taline Khroyan

Journal of Pharmacology and Experimental Therapeutics, 2006

View PDFchevron_right

Novel Mixed NOP/Opioid Receptor Peptide Agonists

VICTOR HOLANDA

Journal of Medicinal Chemistry, 2021

View PDFchevron_right

Spinal and local peripheral antiallodynic activity of Ro64-6198 in neuropathic pain in the rat

Barbara Przewlocka, Ilona Obara

Pain, 2005

View PDFchevron_right

Morphine peripheral analgesia depends on activation of the PI3K /AKT/nNOS/NO/KATP signaling pathway

Fernando Guilherme Moura

Proceedings of The National Academy of Sciences, 2010

View PDFchevron_right

Antinociceptive and anti-allodynic effects of oral PL37, a complete inhibitor of enkephalin-catabolizing enzymes, in a rat model of peripheral neuropathic pain induced by vincristine

Taline Khroyan

European Journal of Pharmacology, 2008

View PDFchevron_right

GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice

Mauro Quartaroli

European Journal of Pharmacology, 2001

View PDFchevron_right

Quantitative study of [(pF)Phe4,Arg14,Lys15]nociceptin/orphanin FQ-NH2 (UFP-102) at NOP receptors in rat periaqueductal gray slices

Lih-chu Chiou

European Journal of Pharmacology, 2008

View PDFchevron_right

Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level

Javier Garzón

British Journal of Pharmacology, 2012

View PDFchevron_right

The Role of Nitric Oxide in the Local Antiallodynic and Antihyperalgesic Effects and Expression of Opioid and Cannabinoid2 Receptors during Neuropathic Pain in Mice

Jesus Campos

Journal of Pharmacology and Experimental Therapeutics, 2010

View PDFchevron_right