Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study (original) (raw)

Inferring statin-induced gene regulatory relationships in primary human hepatocytes

Maria Thomas

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Effects of high-dose statin on the human hepatic expression of genes involved in carbohydrate and triglyceride metabolism

Camilla Pramfalk

Journal of internal medicine, 2011

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Variability in statin-induced changes in gene expression profiles of pancreatic cancer

Helena Gbelcova

Scientific reports, 2017

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Investigating the Effects of Statins on Cellular Lipid Metabolism Using a Yeast Expression System

Beata Burzynska

PLoS ONE, 2009

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The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase

Beata Burzynska

BMC Biotechnology, 2013

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Don’t Judge a Book by Its Cover: The Role of Statins in Liver Cancer

Miroslaw Kornek

Cancers

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Comparison of Transcriptomic Profiles of MiaPaCa-2 Pancreatic Cancer Cells Treated with Different Statins

Helena Gbelcova

Molecules, 2021

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Impact of Statins on Gene Expression in Human Lung Tissues

Stephan Van Eeden

PloS one, 2015

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Statins Activate Human PPAR𝛼 Promoter and Increase PPAR𝛼 mRNA Expression and Activation in HepG2 Cells

Masaaki Ikeda

PPAR Research, 2008

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Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

Alun Hughes

Journal of the American College of Cardiology, 2016

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Statins and Cancer Development

Ahmed El-sohemy

Cancer Epidemiology Biomarkers & Prevention, 2005

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Hepatic transcriptomic signatures of statin treatment are associated with impaired glucose homeostasis in severely obese patients

Violeta Raverdy

BMC Medical Genomics, 2019

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Statin use, HMGCR expression, and breast cancer survival – The Malmö Diet and Cancer Study

Maria Inasu

Scientific Reports, 2020

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Review Statins and cancers

Tomasz Góra

Współczesna Onkologia, 2014

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Chemoprevention for hepatocellular carcinoma: the role of statins

Giuseppe Cabibbo

Hepatobiliary surgery and nutrition, 2013

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Statins: Perspectives in cancer therapeutics

Laurent Corcos

Digestive and Liver Disease, 2013

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Pharmacological Actions of Statins: A Critical Appraisal in the Management of Cancer

Elena Ciaglia

Pharmacological Reviews, 2012

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Statins for prevention of hepatocellular cancer: One step closer?

Siddharth Singh

Hepatology, 2014

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Sterol Regulatory Element Binding Protein-Mediated Effect of Fluvastatin on Cytosolic 3-Hydroxy-3-methylglutaryl-Coenzyme A Synthase Transcription

Diego Haro

Archives of Biochemistry and Biophysics, 2000

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Highly variable biological effects of statins on cancer, non-cancer, and stem cells in vitro

Helena Gbelcova

Scientific reports, 2024

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Statins in liver disease: A molehill, an iceberg, or neither?

Curtis Argo, Amedeo Lonardo

Hepatology, 2008

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Statins-from bench to bedside

Gabriela Gheorghe

2014

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Differential metabolic actions of specific statins: clinical and therapeutic considerations

Soo Lim

Antioxidants & redox signaling, 2014

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STAT5A and STAT5B have opposite correlations with drug response gene expression

Faming Liang

Biochemical and Biophysical Research Communications, 2016

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Statins modulate transcriptional activity of heme‐oxygenase‐1 promoter in NIH 3T3 Cells

Jawed Alam

Journal of Cellular Biochemistry, 2012

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Functional expression of human HMG-CoA reductase in Saccharomyces cerevisiae : a system to analyse normal and mutated versions of the enzyme in the context of statin treatment

Beata Burzynska

Journal of Applied Microbiology, 2009

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Statins - the Holy Grail for cancer?

Siddharth Singh

Annals of translational medicine, 2013

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Cholesterol and Its Metabolites in Tumor Growth: Therapeutic Potential of Statins in Cancer Treatment

Vittoria Rago

Frontiers in Endocrinology, 2019

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