Transforming growth factor-β signalling: Role and consequences of Smad linker region phosphorylation
Danielle Kamato, Terrence J Piva, Narin Osman
Cellular Signalling, 2013
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Smad linker region phosphorylation is a signalling pathway in its own right and not only a modulator of canonical TGF-β signalling
Raafat Mohamed
Cellular and Molecular Life Sciences, 2019
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Smad7 and protein phosphatase 1α are critical determinants in the duration of TGF-β/ALK1 signaling in endothelial cells
Carl-henrik Heldin, Marie-josé Goumans
2006
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Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling
Maria Radu
PloS one, 2012
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Smad2 Mediates Transforming Growth Factor-beta Induction of Endothelial Nitric Oxide Synthase Expression
Marta Saura
Circulation Research, 2002
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Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-β signaling
Danielle Martinez
Journal of Biological …, 2006
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KLF2 Suppresses TGF- Signaling in Endothelium Through Induction of Smad7 and Inhibition of AP-1
Reinier Boon
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
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TGF-β induces proangiogenic and antiangiogenic factorsvia parallel but distinct Smad pathways1
Hui Lan
Kidney International, 2004
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Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases
M. Caestecker
Genes & Development, 1998
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CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor transcriptional responses in endothelial cells
Dean Falb
Proceedings of the National Academy of Sciences, 1998
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CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor β transcriptional responses in endothelial cells
Dean Falb
Proceedings of the National Academy of Sciences, 1998
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TGF-β and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions
Hirofumi Matsui
Oncogene, 2004
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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
Paschalis Sideras
The EMBO Journal, 2002
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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
Serhiy Souchelnytskyi
The EMBO Journal, 1997
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Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo
Eve Seuntjens
Cytokine & growth factor reviews
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Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling
Xiaohua Yan
Biochemical Journal, 2011
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TGF-β through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation
Evan Ryer
American Journal of Physiology-Heart and Circulatory Physiology, 2009
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A Negative Feedback Control of Transforming Growth Factor- Signaling by Glycogen Synthase Kinase 3-mediated Smad3 Linker Phosphorylation at Ser-204
Mary Heller
Journal of Biological Chemistry, 2009
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Data from Molecular Imaging of TGFβ-Induced Smad2/3 Phosphorylation Reveals a Role for Receptor Tyrosine Kinases in Modulating TGFβ Signaling
Alnawaz Rehemtulla
2023
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Identification of novel Smad2 and Smad3 associated proteins in response to TGF-β1
Brian Law
Journal of Cellular Biochemistry, 2008
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Transforming growth factor-β1-induced endothelial barrier dysfunction involves Smad2-dependent p38 activation and subsequent RhoA activation
Christopher Shannon
Journal of Applied Physiology, 2006
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Mechanisms of PAR-1 mediated kinase receptor transactivation: Smad linker region phosphorylation
Hang Ta
Journal of Cell Communication and Signaling, 2019
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Smad proteins and transforming growth factor-beta signaling
Markus Bitzer
Kidney International, 2000
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SMAD regulation in TGF-beta signal transduction
Carl-henrik Heldin
Journal of Cell Science
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Smad regulation in TGF-β signal transduction
Serhiy Souchelnytskyi
Journal of Cell Science, 2001
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Protein Kinase A Modulates Transforming Growth Factor- Signaling through a Direct Interaction with Smad4 Protein
Michael Uhler
Journal of Biological Chemistry, 2013
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Functional Characterization of Transforming Growth Factor beta Signaling in Smad2- and Smad3-deficient Fibroblasts
Raju Kucherlapati
Journal of Biological Chemistry, 2001
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Regulation of TGF-β signaling by Smad7
Xiaohua Yan
Acta Biochimica et Biophysica Sinica
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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
Rainer Heuchel, Carl-henrik Heldin
Nature, 1997
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Nitric Oxide Regulates Transforming Growth Factor- Signaling in Endothelial Cells
Marta Saura
Circulation Research, 2005
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