Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus (original) (raw)

Order of amino acids in C-terminal cysteine-containing peptide-based chelators influences cellular processing and biodistribution of 99mTc-labeled recombinant Affibody molecules

Seyed Jalal Hosseinimehr

Amino Acids, 2012

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Development and preclinical characterisation of 99m Tc-labelled Affibody molecules with reduced renal uptake

Thuy Tran

European Journal of Nuclear Medicine and Molecular Imaging, 2008

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Molecular Design and Optimization of 99mTc-Labeled Recombinant Affibody Molecules Improves Their Biodistribution and Imaging Properties

Seyed Jalal Hosseinimehr

Journal of Nuclear Medicine, 2011

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Positioning of 99mTc-chelators influences radiolabeling, stability and biodistribution of Affibody molecules

Joachim Feldwisch

Bioorganic & Medicinal Chemistry Letters, 2009

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In Vivo Evaluation of Cysteine-Based Chelators for Attachment of 99m Tc to Tumor-Targeting Affibody Molecules

Anna Orlova, Vladimir Tolmachev

Bioconjugate Chemistry, 2007

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HAHAHA, HEHEHE, HIHIHI, or HKHKHK: Influence of Position and Composition of Histidine Containing Tags on Biodistribution of [ 99m Tc(CO) 3 ] + -Labeled Affibody Molecules

Seyed Jalal Hosseinimehr

Journal of Medicinal Chemistry, 2013

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In Vivo Evaluation of Cysteine-Based Chelators for Attachment of 99mTc to Tumor-Targeting Affibody Molecules

Alexander Bruskin

Bioconjugate Chemistry, 2007

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Influence of valency and labelling chemistry on in vivo targeting using radioiodinated HER2-binding Affibody molecules

Vladimir Tolmachev

European Journal of Nuclear Medicine and Molecular Imaging, 2009

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Selection of an optimal cysteine-containing peptide-based chelator for labeling of affibody molecules with (188)Re

Anna Orlova, Z. Varasteh, Vladimir Tolmachev

European journal of medicinal chemistry, 2014

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99m Tc-chelator engineering to improve tumour targeting properties of a HER2-specific Affibody molecule

lars abrahmsen

European Journal of Nuclear Medicine and Molecular Imaging, 2007

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Site-specific radioiodination of an anti-HER2 single domain antibody fragment with a residualizing prosthetic agent

Darryl McDougald

Nuclear Medicine and Biology, 2020

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Evaluation of Maleimide Derivative of DOTA for Site-Specific Labeling of Recombinant Affibody Molecules

Mattias Sandström

Bioconjugate Chemistry, 2008

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New small 99mTc-labeled peptides for HER2 receptor imaging

hamideh sabahnoo

European Journal of Medicinal Chemistry, 2017

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Comparative Preclinical Evaluation of Peptide-Based Chelators for Labeling of DARPin G3 with 99mTc for Radionuclide Imaging of HER2 Expression in Cancer

Evgenii Plotnikov

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Kit formulation for 99mTc-labeling of recombinant anti-HER2 Affibody molecules with a C-terminally engineered cysteine

Vladimir Tolmachev

Nuclear medicine and biology, 2010

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Targeting of HER2Expressing Tumors with a Site-Specifically 99mTc-Labeled Recombinant Affibody Molecule, ZHER2:2395, with C-Terminally Engineered Cysteine

lars abrahmsen

Journal of Nuclear Medicine, 2009

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Preclinical Evaluation of 99mTc-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

Joachim Feldwisch

International Journal of Molecular Sciences

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Site-Specific Radiometal Labeling and Improved Biodistribution Using ABY-027, A Novel HER2-Targeting Affibody Molecule-Albumin-Binding Domain Fusion Protein

Hans Lundqvist

Journal of Nuclear Medicine, 2013

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Reduction of renal activity retention of radiolabeled albumin binding domain‑derived affinity proteins using a non‑residualizing label strategy compared with a cleavable glycine‑leucine‑glycine‑lysine‑linker

maryam oroujeni

Molecular Medicine Reports, 2023

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99mTc-HYNIC-derivatized ternary ligand complexes for 99mTc-labeled polypeptides with low in vivo protein binding

Kazuma Ogawa

Nuclear Medicine and Biology, 2001

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Plasma protein binding of 99mTc-labeled hydrazino nicotinamide derivatized polypeptides and peptides

Kazuma Ogawa

Nuclear Medicine and Biology, 2001

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Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m

Javad Garousi

Scientific reports, 2017

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Imaging of HER2-expressing tumours using a synthetic Affibody molecule containing the 99mTc-chelating mercaptoacetyl-glycyl-glycyl-glycyl (MAG3) sequence

Anna Orlova, Vladimir Tolmachev

European Journal of Nuclear Medicine and Molecular Imaging, 2007

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