Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II (original) (raw)

Thapsigargin-induced Ca2+ increase inhibits TGFβ1-mediated Smad2 transcriptional responses via Ca2+/calmodulin-dependent protein kinase II

Björn Spittau, Kerstin Krieglstein

Journal of Cellular Biochemistry, 2010

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Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4

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A Transforming Growth Factor -Induced Smad3/Smad4 Complex Directly Activates Protein Kinase A

Michael Uhler

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Functional Characterization of Transforming Growth Factor beta Signaling in Smad2- and Smad3-deficient Fibroblasts

Raju Kucherlapati

Journal of Biological Chemistry, 2001

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Protein Kinase A Modulates Transforming Growth Factor- Signaling through a Direct Interaction with Smad4 Protein

Michael Uhler

Journal of Biological Chemistry, 2013

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Identification of novel Smad2 and Smad3 associated proteins in response to TGF-β1

Brian Law

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Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling

Xiaohua Yan

Biochemical Journal, 2011

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Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4

Anke Klippel

Oncogene, 2003

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

Serhiy Souchelnytskyi

The EMBO Journal, 1997

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Smad7 Differentially Regulates Transforming Growth Factor β-mediated Signaling Pathways

Andrew Sizeland

Journal of Biological Chemistry, 1999

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Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-beta Signaling

Serhiy Souchelnytskyi

Journal of Biological Chemistry, 1997

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Smad7 Differentially Regulates Transforming Growth Factor beta -mediated Signaling Pathways

J. Iaria

Journal of Biological Chemistry, 1999

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Evidence That Smad2 Is a Tumor Suppressor Implicated in the Control of Cellular Invasion

M. Mareel

Journal of Biological Chemistry, 1999

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Phosphorylation of Smad7 at Ser-249 Does Not Interfere with Its Inhibitory Role in Transforming Growth Factor-β-dependent Signaling but Affects Smad7-dependent Transcriptional Activation

Serhiy Souchelnytskyi

Journal of Biological Chemistry, 2001

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Transforming growth factor-β signalling: Role and consequences of Smad linker region phosphorylation

Danielle Kamato, Terrence J Piva, Narin Osman

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The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling

Hidetoshi Hayashi

Cell, 1997

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Regulation of TGF-β signaling by Smad7

Xiaohua Yan

Acta Biochimica et Biophysica Sinica

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Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases

M. Caestecker

Genes & Development, 1998

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Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-β signaling

Danielle Martinez

Journal of Biological …, 2006

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Smad proteins and transforming growth factor-beta signaling

Markus Bitzer

Kidney International, 2000

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Internalization-Dependent and Independent Requirements for Transforming Growth Factor Receptor Signaling via the Smad Pathway

Nandor Garamszegi

Molecular and Cellular Biology, 2002

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Sphingosine 1-Phosphate Cross-activates the Smad Signaling Cascade and Mimics Transforming Growth Factor- -induced Cell Responses

Heinfried Radeke

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Signaling of transforming growth factor-β family members through Smad proteins

Marie-Jose Goumans

European Journal of Biochemistry, 2000

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Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo

Eve Seuntjens

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Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling

Maria Radu

PloS one, 2012

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

Rainer Heuchel, Carl-henrik Heldin

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Regulation of Smad signaling by protein kinase C

Carl-henrik Heldin

The FASEB Journal, 2001

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TLP, a novel modulator of TGF- signaling, has opposite effects on Smad2- and Smad3-dependent signaling

James McNally

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SMAD regulation in TGF-beta signal transduction

Carl-henrik Heldin

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Transcriptional regulation of Smad2 is required for enhancement of TGF?/Smad signaling by TGF? inducible early gene

Thomas Spelsberg

Journal of Cellular Biochemistry, 2002

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The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

Barbara Hocevar

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Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway

Edward Leof

Molecular and Cellular Biology, 2002

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