Synthesis and evaluation of chalcone analogues and pyrimidines as cyclooxygenase (COX) inhibitors (original) (raw)
Effects of anti-cyclooxygenases (COX-1 and COX-2), structure activity relationship, molecular docking and in silico ADMET of some synthesized chalcones
Mohammed Al-Mamary
Tropical Journal of Pharmaceutical Research
View PDFchevron_right
Synthesis and In Silico Analysis of Chalcone Derivatives as Potential Prostaglandin Synthetase Inhibitors
SAMUEL J . BUNU
Biomedical journal of scientific & technical research, 2024
View PDFchevron_right
Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach
Richard I Hall
Bioorganic & Medicinal Chemistry Letters, 2009
View PDFchevron_right
Synthesis and biological evaluation of novel series of chalcone derivatives as inhibitors of cyclooxygenase and LPS-induced TNF-α with potent antioxidant properties
Nagesh A Dhole
Medicinal Chemistry Research
View PDFchevron_right
Dual evaluation of some novel chalcone annulated pyrazolines as anti-inflammatory and antimicrobial agents via in-silico target study on cyclooxygenase-2
Latha Subbiah
International Journal of Research in Pharmaceutical Sciences, 2019
View PDFchevron_right
Synthesis of Hydroxybenzofuranyl-pyrazolyl and Hydroxyphenyl-pyrazolyl Chalcones and Their Corresponding Pyrazoline Derivatives as COX Inhibitors, Anti-inflammatory and Gastroprotective Agents
Gehad Abdel Jaleel
Chemical and Pharmaceutical Bulletin, 2020
View PDFchevron_right
Phenylsulphonyl urenyl chalcone derivatives as dual inhibitors of cyclo-oxygenase-2 and 5-lipoxygenase
Caritza Leon
Life Sciences, 2006
View PDFchevron_right
Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines
Ingebrigt Sylte
Drug Design, Development and Therapy, 2014
View PDFchevron_right
3) Structure–activity relationships for the synthesis of selective cyclooxygenase 2 inhibitors an overview (2009–2016).pdf
Gabriele Carullo, Francesca Aiello
View PDFchevron_right
Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors
Spencer Williams
Bioorganic & Medicinal Chemistry Letters, 2009
View PDFchevron_right
2-Heterosubstituted-3-(4-methylsulfonyl)phenyl-5-trifluoromethyl pyridines as selective and orally active cyclooxygenase-2 inhibitors
denis deschenes
Bioorganic & Medicinal Chemistry Letters, 1999
View PDFchevron_right
Synthesis, biological evaluation, and docking analysis of a novel family of 1-methyl-1H-pyrrole-2,5-diones as highly potent and selective cyclooxygenase-2 (COX-2) inhibitors
Jelena Penjišević
Bioorganic & Medicinal Chemistry Letters, 2014
View PDFchevron_right
Synthesis and pharmacological evaluation of m-terphenyl amines as cyclooxygenase inhibitors
Michael Foster
Medicinal Chemistry …, 2007
View PDFchevron_right
Design and synthesis of new 2-aryl, 3-benzyl-(1,3-oxazolidine or 1,3-thiazolidine)-4-ones as selective cyclooxygenase (COX-2) inhibitors
Susan Torabi
2010
View PDFchevron_right
Discovery of Bis-sydnone styryl ketone as a selective cyclooxygenase-2 inhibitor
Mohamed Alaama
Future Journal of Pharmaceutical Sciences
View PDFchevron_right
Synthesis and Angiotensin Converting Enzyme (ACE) inhibition activity of chalcone derivatives
Giancarlo Statti
Planta Medica, 2007
View PDFchevron_right
2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors
denis deschenes
Bioorganic & Medicinal Chemistry Letters, 1998
View PDFchevron_right
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimi-dinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors
Neil Mathews
Bioorganic Medicinal Chemistry Letters, 2009
View PDFchevron_right
A new pyrazolo pyrimidine derivative inhibitor of cyclooxygenase-2 with anti-angiogenic activity
Ricardo Riguera
European Journal of Pharmacology, 2004
View PDFchevron_right
Synthesis and biological evaluation of new benzo-thieno[3,2-d]pyrimidin-4-one sulphonamide thio-derivatives as potential selective cyclooxygenase-2 inhibitors
Agostino Marrazzo, Mariarita Barone
Molecular Diversity, 2013
View PDFchevron_right
EGFR and COX-2 Dual Inhibitor: The Design, Synthesis, and Biological Evaluation of Novel Chalcones
Arafa Kassem
Molecules, 2022
View PDFchevron_right
Synthesis and Characterization of Novel IMIDAZO[1,2- A]Pyridine Derivatives as Potential CYCLOOXYGENASE-2 (COX-2) Inhibitors
shivaji Pandit
2018
View PDFchevron_right
Synthesis, Cyclooxygenases Inhibition Activities and Interactions with BSA of N-substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones Derivatives
Tomasz Gębarowski
Molecules
View PDFchevron_right
Synthesis of potential anti-inflammatory compounds, selective inhibitors of cyclooxygenase-2 (COX-2)
Francisco López-muñoz
View PDFchevron_right
Dual evaluation of some novel chalcone annulated pyrazolines as anti-in lammatory and antimicrobial agents via in-silico target study on cyclooxygenase-2 Production and Hosted by
Selvamani Palanisamy
INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES , 2019
View PDFchevron_right
Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors
Farshad Shirazi
Bioorganic & Medicinal Chemistry, 2006
View PDFchevron_right
Brief Articles 1,5-Diarylpyrrole-3-acetic Acids and Esters as Novel Classes of Potent and Highly Selective Cyclooxygenase-2 Inhibitors
Maurizio Anzini
2004
View PDFchevron_right
Synthesis and evaluation of novel pyrrolidine chalcone derivatives with anticancer, anti-inflammatory and antibacterial activities
siva sanker reddy.L
2015
View PDFchevron_right
Synthesis, Anti-Inflammatory Activity, and in Vitro Antitumor Effect of a Novel Class of Cyclooxygenase Inhibitors: 4-(Aryloyl)phenyl Methyl Sulfones
Maria Cusimano
Journal of Medicinal Chemistry, 2010
View PDFchevron_right
Synthesis and evaluation of novel pyrrolidine chalcone derivatives with anticancer.pdf
siva sanker reddy.L
View PDFchevron_right
CHALCONES AS INOS AND COX-2 INHIBITORS; INSIGHTS FROM MOLECULAR DOCKING STUDIES
shaheen begum
View PDFchevron_right