Interdomain but Not Intermolecular Interactions Observed in CFTR Channels (original) (raw)
Redox Reagents and Divalent Cations Alter the Kinetics of Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating
Melissa Harrington
Journal of Biological Chemistry, 1999
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Cysteine Residues in the Nucleotide Binding Domains Regulate the Conductance State of CFTR Channels
Melissa Harrington
Biophysical Journal, 2002
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Multiple Membrane-Cytoplasmic Domain Contacts in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mediate Regulation of Channel Gating
Nikolay Dokholyan
Journal of Biological Chemistry, 2008
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The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating
Xiu-Bao Chang, Andrei Aleksandrov
The Journal of Physiology, 2000
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Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment
E. Guiraldes
Biophysical Journal, 1996
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The First Nucleotide Binding Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is a Site of Stable Nucleotide Interaction, whereas the Second Is a Site of Rapid Turnover
Xiu-Bao Chang, Andrei Aleksandrov
Journal of Biological Chemistry, 2002
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Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator
Andrei Aleksandrov
The Journal of Physiology, 2009
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Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop
Kevin Kirk
The Journal of biological chemistry, 2015
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Conformational change of the extracellular parts of the CFTR protein during channel gating
Elizabeth Cowley
Cellular and molecular life sciences : CMLS, 2018
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Asymmetric Structure of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore Suggested by Mutagenesis of the Twelfth Transmembrane Region †
Jyoti Gupta
Biochemistry, 2001
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Conformational Changes Relevant to Channel Activity and Folding within the first Nucleotide Binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator
ori kalid, H. Bihler
Journal of Biological Chemistry, 2012
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The H-loop in the Second Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator is Required for Efficient Chloride Channel …
Michal Milewski
Cellular Physiology …, 2010
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Chloride Channel and Chloride Conductance Regulator Domains of CFTR, the Cystic Fibrosis Transmembrane Conductance Regulator
Erik Schwiebert
Proceedings of the …, 1998
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The H-loop in the Second Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator is Required for Efficient Chloride Channel Closing
Michał Milewski
Cellular Physiology and Biochemistry, 2010
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C Terminus of Nucleotide Binding Domain 1 Contains Critical Features for Cystic Fibrosis Transmembrane Conductance Regulator Trafficking and Activation
Frédéric Becq
Journal of Biological Chemistry, 2010
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A Topological Switch in the Cystic Fibrosis Transmembrane Conductance Regulator Modulates Channel Activity and Sensitivity to Disease-Causing Mutation
Maud Sigoillot
2020
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Activating Cystic Fibrosis Transmembrane Conductance Regulator Channels with Pore Blocker Analogs
Kevin Kirk
Journal of Biological Chemistry, 2005
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Two Small Molecules Restore Stability to a Sub-population of the Cystic Fibrosis Transmembrane conductance Regulator with the Predominant Disease-causing Mutation
Robert Ford
The Journal of biological chemistry, 2017
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Structure and function of the cystic fibrosis transmembrane conductance regulator
anibal lopes
Brazilian Journal of Medical and Biological Research, 1999
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Purification and Crystallization of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
Robert Ford
Journal of Biological Chemistry, 2004
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Differential Interactions of Nucleotides at the Two Nucleotide Binding Domains of the Cystic Fibrosis Transmembrane Conductance Regulator
Andrei Aleksandrov
Journal of Biological Chemistry, 2001
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Destabilization of the Transmembrane Domain Induces Misfolding in a Phenotypic Mutant of Cystic Fibrosis Transmembrane Conductance Regulator
Anthony Partridge, Craig Daniels
Journal of Biological Chemistry, 2004
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Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Cl- Channel by Its R Domain
Olafur Baldursson
Journal of Biological Chemistry, 2001
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Stability to a Sub-population of the Cystic Fibrosis Transmembrane conductance Regulator with the Predominant Disease-causing
Robert Ford
2017
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Characterization of the internalization pathways for the cystic fibrosis transmembrane conductance regulator
Neil Bradbury
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Location of a permeant anion binding site in the cystic fibrosis transmembrane conductance regulator chloride channel pore
Hussein Rubaiy
The journal of physiological sciences : JPS, 2015
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Functional organization of cytoplasmic portals controlling access to the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel pore
Elizabeth Cowley
The Journal of biological chemistry, 2018
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Variable Reactivity of an Engineered Cysteine at Position 338 in Cystic Fibrosis Transmembrane Conductance Regulator Reflects Different Chemical States of the Thiol
Jose Serrano-Moreno, David Dawson
Journal of Biological Chemistry, 2006
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