Prostaglandin E 2 Strongly Inhibits Human Osteoclast Formation (original) (raw)

Inhibitory and stimulatory effects of prostaglandins on osteoclast differentiation

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Calcified Tissue International, 1997

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Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture

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Prostaglandin E2 Directly Inhibits Bone-Resorbing Activity of Isolated Mature Osteoclasts Mainly Through the EP4 Receptor

M MANO

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Prostaglandin production by human osteoclasts in culture

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Prostaglandin E2 (PGE2) increases the number of rat bone marrow osteogenic stromal cells (BMSC) via binding the EP4 receptor, activating sphingosine kinase and inhibiting caspase activity

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Effects of exogenous prostanoids on the proliferation of osteoblast-like cells in vitro

Clemens Lowik

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Systemic administration of an anabolic dose of PGE2 in young rats increases the osteogenic capacity of bone marrow

S. Keila

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1,25-Dihydroxyvitamin D3 and Prostaglandin E2 Act Directly on Circulating Human Osteoclast Precursors

Afsie Sabokbar

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Effects of prostaglandins on rat calvarial bone-cell calcium

Rosemary Dziak

Archives of Oral Biology, 1984

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Stimulation of prostaglandin E2 (PGE2) production by arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1 osteoblast-like cells

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Prostaglandin Receptor EP4Mediates the Bone Anabolic Effects of PGE2

Michel Gallant

Molecular Pharmacology, 2001

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Effects of prostaglandin E2 on macrophages and osteoclasts in cultured fetal long bones

B. Rifkin

Cell and Tissue Research, 1980

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Activation of Protease-Activated Receptor-2 Leads to Inhibition of Osteoclast Differentiation

Liliana Tatarczuch

Journal of Bone and Mineral Research, 2003

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Biphasic influence of PGE2 on the resorption activity of osteoclast-like cells derived from human peripheral blood monocytes and mouse RAW264.7 cells

Ursula Anderer

Prostaglandins, leukotrienes, and essential fatty acids, 2016

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Characterization of the prostaglandin receptors in human osteoblasts in culture

Ghassan Bkaily

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Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation

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Proceedings of the National Academy of Sciences, 2002

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Effects of arachidonic acid, docosahexaenoic acid, prostaglandin E2 and parathyroid hormone on osteoprotegerin and RANKL secretion by MC3T3-E1 osteoblast-like cells

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The Journal of Nutritional Biochemistry, 2007

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Osteotropic cytokines mediate human osteoblast-like cell eicosanoid production

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Regulation of bone biology by prostaglandin endoperoxide H synthases (PGHS): A rose by any other name…

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Prostaglandin E2 Stimulates Bone Sialoprotein (BSP) Expression through cAMP and Fibroblast Growth Factor 2 Response Elements in the Proximal Promoter of the Rat BSP Gene

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Regulation of prostaglandin production by osteoblast-rich calvarial cells

Roger Nolan, N. Partridge

Prostaglandins, 1985

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Systemic prostaglandin E2 increases cancellous bone formation and mass in aging rats and stimulates their bone marrow osteogenic capacity in vivo and in vitro

S. Keila

Journal of Endocrinology, 2001

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Parathyroid hormone and prostaglandin E 2 stimulate both inositol phosphates and cyclic AMP accumulation in mouse osteoblast cultures

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Biochemical Journal, 1988

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Cross-Talk between the Interleukin-6 and Prostaglandin E 2 Signaling Systems Results in Enhancement of Osteoclastogenesis through Effects on the Osteoprotegerin/Receptor Activator of Nuclear Factor-κB (RANK) Ligand/RANK System

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Effects of bovine parathyroid hormone and 1,25-dihydroxyvitamin D3 on the production of prostaglandins by cells derived from human bone

Graham Russell

FEBS Letters, 1984

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The Role of Prostaglandin E Receptor Subtypes (EP1, EP2, EP3, and EP4) in Bone Resorption: An Analysis Using Specific Agonists for the Respective EPs

Yukihiko Sugimoto

Endocrinology, 2000

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Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms

Charles O'Brien

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Effect of mechanical strain-induced PGE2 production on bone nodule formation by rat calvarial progenitor cells

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Lipoxygenase metabolites are mediators of PTH-dependent human osteoblast growth

Sara Katzburg

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Inhibition of cyclooxygenase-2 down-regulates osteoclast and osteoblast differentiation and favours adipocyte formation in vitro

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Isolation of a Novel Cytokine From Human Fibroblasts That Specifically Inhibits Osteoclastogenesis

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Inflammatory cytokines regulate proliferation of cultured human osteoblasts

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Acta Orthopaedica, 1997

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