Antagonism/Agonism Modulation to Build Novel Antihypertensives Selectively Triggering I 1 -Imidazoline Receptor Activation (original) (raw)

Imidazoline Antihypertensive Drugs: Selective I1-Imidazoline Receptors Activation

Cardiovascular Therapeutics, 2012

Characterization of Imidazoline Receptors in Blood Vessels for the Development of Antihypertensive Agents

BioMed Research International, 2014

Synthesis and Antihypertensive Action of New Imidazo[1,2-a]pyridine Derivatives , non Peptidic Angiotensin II Receptor Antagonists

Sonia Laneri

Cardiovascular & Hematological Disorders-Drug Targets, 2011

View PDFchevron_right

Selective imidazoline receptor agonists: redefining role of centrally acting agents in role of centrally acting agents in management of hypertension

Anil S Bhoraskar

International Journal of Advances in Medicine, 2019

View PDFchevron_right

Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome

Arvind kumar

Journal of medicinal chemistry, 2015

View PDFchevron_right

Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites.

Paul Ernsberger

… of Pharmacology and …, 1993

View PDFchevron_right

New 2-Aminothiazoline derivatives lower blood pressure of spontaneously hypertensive rats (SHR) via I1-imidazoline and alpha-2 adrenergic receptors activation

Wanda Pereira Almeida

European journal of pharmacology, 2016

View PDFchevron_right

QSAR study of imidazoline antihypertensive drugs

Katarina Nikolic

Bioorganic & Medicinal Chemistry, 2008

View PDFchevron_right

Importance of Imidazoline Receptors in the Cardiovascular Actions of Centrally Acting Antihypertensive Agents

Geoffrey Head

Annals of the New York Academy of Sciences, 1995

View PDFchevron_right

Synthesis Study of New 2-SUBSTITUTED Imidazolines with Potential Hypotensive Activity

Adina Dumitrascu

Southern Brazilian Journal of Chemistry, 1998

View PDFchevron_right

Synthesis, binding studies and in vivo biological evaluation of novel non-peptide antihypertensive analogues

P. Moutevelis-minakakis, Christoforos Kokotos, T. Mavromoustakos, Panagiotis Zoumpoulakis

Bioorganic & Medicinal Chemistry, 2006

View PDFchevron_right

Role of imidazoline receptors in cardiovascular regulation

H. Greney

The American Journal of Cardiology, 1994

View PDFchevron_right

A novel mechanism of action for hypertension control: Moxonidine as a selective I 1-imidazoline agonist

Paul Ernsberger

… drugs and therapy, 1994

View PDFchevron_right

Synthesis and biological affinity of new imidazo- and indol-arylpiperazine derivatives: Further validation of a pharmacophore model for α1-adrenoceptor antagonists

Laura Betti

Bioorganic & Medicinal Chemistry Letters, 2008

View PDFchevron_right

α 1 -Adrenoceptor Antagonists. 4. 1 Pharmacophore-Based Design, Synthesis, and Biological Evaluation of New Imidazo-, Benzimidazo-, and Indoloarylpiperazine Derivatives

Laura Betti

Journal of Medicinal Chemistry, 2002

View PDFchevron_right

Synthesis and biological evaluation of novel antihypertensive compounds

lys mendes

Chem, 2016

View PDFchevron_right

Nonpeptide angiotensin II antagonists derived from 1H-pyrazole-5-carboxylates and 4-aryl-1H-imidazole-5-carboxylates

Richard Strelitz

Journal of Medicinal Chemistry, 1993

View PDFchevron_right

Imidazoline-1 Receptor Ligands as Apoptotic Agents: Pharmacophore Modeling and Virtual Docking Study

Agbaba Danica, Tatjana Srdic-Rajic

Combinatorial Chemistry & High Throughput Screening, 2013

View PDFchevron_right

Design, Synthesis and Pharmacological Screening of Novel Antihypertensive Agents Using Hybrid Approach

Suraj Gore

Bioorganic & Medicinal Chemistry, 2009

View PDFchevron_right

Recent advances in selective α1-adrenoreceptor antagonists as antihypertensive agents

Mange Ram Yadav

Bioorganic & Medicinal Chemistry, 2008

View PDFchevron_right

A convenient method for 14C-labeling of 2-methylthio-1-[4-N-α-ethoxycarbonylbenzyl)-amino-benzyl]-5-hydroxymethyl-2-[14C]-1H-imidazole and 1-[4-N-α-ethoxy-carbonylbenzyl)-aminobenzyl]-5-hydroxymethyl-2-[14C]-1H-imidazole as potential antihypertensives

mohsen Javaheri

Journal of Radioanalytical and Nuclear Chemistry, 2011

View PDFchevron_right

Design and synthesis of novel antihypertensive drugs

P. Moutevelis-minakakis

Bioorganic & Medicinal Chemistry Letters, 2003

View PDFchevron_right

Imidazoline antihypertensive drugs: a critical review on their mechanism of action

Bela Szabo

Pharmacology & Therapeutics, 2002

View PDFchevron_right

Design, synthesis, and antihypertensive evaluation of 2′-tetrazolyl and 2′-carboxy-biphenylylmethyl-pyrrolidine scaffolds substituted at their N1, C3, and C4 positions as potential angiotensin II AT1 receptor antagonists

Nasser Ismail

Medicinal Chemistry Research, 2014

View PDFchevron_right

Quantitative Structure-Activity Relationships (QSARs) Modeling of Anti-hypertensive Activity of Dichloroanilino Imidazoline Derivatives

Arkendu Chatterjee

American Journal of PharmTech Research

View PDFchevron_right

Structureactivity studies of new imidazolines on adrenoceptors of rat aorta and human platelets

Vimon Tantishaiyakul

Naunyn-schmiedebergs Archives of Pharmacology, 1991

View PDFchevron_right

Synthesis and pharmacological screening of some novel anti- hypertensive agents possessing 5-Benzylidene-2-(phenylimino)- thiazolidin-4-one ring

Shashikant V . Bhandari

View PDFchevron_right

Contribution of I1‐Imidazoline Receptors and α2

Heikki Karppanen

1996

View PDFchevron_right

Synthesis, vasorelaxant activity and antihypertensive effect of benzo[d]imidazole derivatives

Julio Cesar Rivera Leyva

Bioorganic & Medicinal Chemistry, 2010

View PDFchevron_right

Antagonism/Agonism Modulation to Build Novel Antihypertensives Selectively Triggering I 1 -Imidazoline Receptor Activation (original) (raw)

Related papers