New findings in the study on the intercalation of bisdaunorubicin and its monomeric analogues with naked and nucleus DNA (original) (raw)

A New Bisintercalating Anthracycline with Picomolar DNA Binding Affinity

Journal of Medicinal Chemistry, 2005

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Binding of Two Novel Bisdaunorubicins to DNA Studied by NMR Spectroscopy † , ‡

Howard Robinson

Biochemistry, 1997

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DNA binding properties and evaluation of cytotoxic activity of 9,10-bis- N-substituted (aminomethyl)anthracenes

International Journal of Biological Macromolecules, 2007

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Protein-associated DNA breaks and DNA-protein cross-links caused by DNA nonbinding derivatives of Adriamycin in L1210 cells. Cancer Res

Cancer Research

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DNA damage and differential cytotoxicity produced in human carcinoma cells by CC-1065 analogues, U-73,975 and U-77,779

Cancer research, 1991

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Comparison of intracellular drug retention, DNA damage and cytotoxicity of derivatives of doxorubicin and daunorubicin in a human colon adenocarcinoma cell line (LoVo)

Maurizio D'Incalci

Biochemical Pharmacology, 1989

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Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells

Paul Kong Thoo Lin, Amanda Gordon

European Journal of Medicinal Chemistry, 2010

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Nuclear Targeting and Nuclear Retention of Anthracycline−Formaldehyde Conjugates Implicates DNA Covalent Bonding in the Cytotoxic Mechanism of Anthracyclines

Chemical Research in Toxicology, 1999

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Interaction of three second-generation anthracyclines with polynucleotides, RNA, DNA, and nucleosomes

Cancer Research

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DNA damage and sequence specificity of DNA binding of the new anti-cancer agent 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane dimaleate (Dabis maleate)

British journal of cancer, 1990

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Effects of the antitumor agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one on the DNA of mouse L1210 cells

Cancer research, 1984

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Design, synthesis, DNA binding, and biological activity of a series of DNA minor-groove-binding intercalating drugs

Christian BAILLY

Journal of Pharmaceutical Sciences, 1989

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Relationships between DNA-binding kinetics and biological activity for the 9-aminoacridine-4-carboxamide class of antitumor agents

Gordon Rewcastle

Journal of medicinal …, 1987

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DNA Sequence Recognition by Bispyrazinonaphthalimides Antitumor Agents

Carolina Carrasco

Biochemistry, 2003

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DNA BINDING AND MUTAGENICITY OF 7-SUBSTITUTED DERIVATIVES OF BENZ[A]ANTHRACENE

Joseph Wettstein

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Pro-apoptotic activity of new analog of anthracyclines - WP 631 in advanced ovarian cancer cell line

2014

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The Mechanism of Action of Nitro-heterocyclic Antimicrobial Drugs. Primary Target of 1-Methyl-2-nitro-5-vinylimidazole is DNA

Journal of General Microbiology, 1977

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Nucleic acid binding drugs—XIV

Biochemical Pharmacology, 1986

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DNA binding-independent anti-proliferative action of benzazolo [3, 2-α] quinolinium DNA intercalators

Molecular and cellular …, 1997

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Role of the Nitro Functionality in the DNA Binding of 3-Nitro-10-methylbenzothiazolo[3,2- a ]quinolinium Chloride

Chemical Research in Toxicology, 2008

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DNA binding-independent anti-proliferative action of benzazolo(3,2-α α α α)quinolinium DNA intercalators

Mol Cell Biochem, 1997

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Kinetics of drug-DNA interaction

Laurence Wakelin

Journal of Molecular Biology, 1980

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A comparative analysis of the time-dependent antiproliferative effects of daunorubicin and WP631

Sylvia Mansilla

European Journal of Biochemistry, 2003

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Comparison of dna scission and cytotoxicity produced by adriamycin and 5-iminodaunorubicin in human colon carcinoma cells

Biochemical Pharmacology, 1983

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Sequence-Selective Intercalation of Antitumour Bis-Naphthalimides into DNA

Christian BAILLY

European Journal of Biochemistry, 1996

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Structural changes of DNA induced by mono- and binuclear cancer drugs

Sabyasachi Sarkar

Journal of Structural Biology, 2005

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The modulation by xanthines of the DNA-damaging effect of polycyclic aromatic agents

Biochemical Pharmacology, 2002

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Different Type of DNA Damage Caused by Three Aziridinyl Substituted Cyclophosphazenes in a Human Small Cell Lung Carcinoma Cell Line

Cancer Research, 1986

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Synthesis structure DNABSA interaction and in vitro cytotoxic activity.pdf

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