Modulation of Aire regulates the expression of tissue-restricted antigens (original) (raw)
Transcriptional regulation by AIRE: molecular mechanisms of central tolerance
Pärt Peterson
Nature Reviews Immunology, 2008
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The Many Faces of Aire in Central Tolerance
Pärt Peterson
Frontiers in Immunology, 2013
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Gene Dosage-limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity
Daniel GRAY
Journal of Experimental Medicine, 2004
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Expression profile of peripheral tissue antigen genes in medullary thymic epithelial cells (mTECs) is dependent on mRNA levels of autoimmune regulator (Aire)
Nicole Pezzi
Immunobiology, 2013
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Faculty of 1000 evaluation for Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
Andrea Sant
F1000 - Post-publication peer review of the biomedical literature, 2004
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A Specific Anti-Aire Antibody Reveals Aire Expression Is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery
Hamish Scott
The Journal of Immunology, 2008
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Autoimmune Regulator Is Expressed in the Cells Regulating Immune Tolerance in Thymus Medulla
Kai Krohn
Biochemical and Biophysical Research Communications, 1999
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Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism
Kim Staats
European Journal of Immunology, 2013
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Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells
Eduardo Donadi
Frontiers in immunology, 2016
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Aire and T cell development
Maureen Su
Current Opinion in Immunology, 2011
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Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells
Claude Perreault
Journal of immunology (Baltimore, Md. : 1950), 2015
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Transcriptional programs that control expression of the autoimmune regulator gene Aire
Ben Levi
Nature immunology, 2016
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Function Critical for Thymic Epithelial Controls the Expression of Genes The Autoimmune Regulator Directly
Kenneth Tung
2010
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Aire-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for Aire in Thymic Epithelial Differentiation
J. Dooley
The Journal of Immunology, 2007
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A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire
Klaus Rajewsky
European Journal of Immunology, 2017
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Defective Central Tolerance in Aire-Deficient Mice is not Sufficient to Induce Symptomatic Autoimmunity During Lymphopenia-Induced T cell Proliferation
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Scandinavian Journal of Immunology, 2011
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Reduced Thymic Aire Expression and Abnormal NF- B2 Signaling in a Model of Systemic Autoimmunity
Maree Hammett, Richard Boyd
The Journal of Immunology, 2009
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Expression of the Autoimmune Regulator Gene and Its Relevance to the Mechanisms of Central and Peripheral Tolerance
Roberto Perniola
Clinical and Developmental Immunology, 2012
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Aire Controls in Trans the Production of Medullary Thymic Epithelial Cells Expressing Ly-6C/Ly-6G
Haruo Kozono
The Journal of Immunology
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The Autoimmune Regulator Directly Controls the Expression of Genes Critical for Thymic Epithelial Function
Sharad Purohit
The Journal of Immunology, 2007
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Beyond APECED: An update on the role of the autoimmune regulator gene (AIRE) in physiology and disease
Francesco Indiveri
Autoimmunity Reviews, 2018
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Autoimmune regulator: from loss of function to autoimmunity
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Genes & Immunity, 2003
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Update on Aire and thymic negative selection
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Models of Aire-Dependent Gene Regulation for Thymic Negative Selection
J. Dooley
Frontiers in Immunology, 2011
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RANK signals from CD4+3 inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
Hamish Scott
Journal of Experimental Medicine, 2007
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The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein
Roberto Perniola
2014
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RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
Stylianos Antonarakis, Kai Krohn, H. Scott, P. Naquet
European Journal of Immunology, 2000
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Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
Maureen Su, Paula Bubulya, Karen Giang
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