Activation of Different Stat5 Isoforms Contributes to Cell-Type- Restricted Signaling in Response to Interferons (original) (raw)

The Stat1 Binding Motif of the Interferon-gamma Receptor Is Sufficient to Mediate Stat5 Activation and Its Repression by SOCS3

Thomas Decker

Journal of Biological Chemistry, 2001

View PDFchevron_right

Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation

Olli Silvennoinen

Molecular and Cellular Biology, 1994

View PDFchevron_right

Cutting Edge: Role of STAT1, STAT3, and STAT5 in IFN-αβ Responses in T Lymphocytes

Robert Arduini

The Journal of Immunology, 2005

View PDFchevron_right

Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages

Ilkka Julkunen

Journal of Immunology, 1997

View PDFchevron_right

STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

Toshio Kitamura

The EMBO Journal, 1999

View PDFchevron_right

Biologic consequences of Stat1-independent IFN signaling

Erwin Bohn

Proceedings of the National Academy of Sciences, 2001

View PDFchevron_right

Lineage-specific activation of STAT3 by interferon-gamma in human neutrophils

Leo Koenderman

Journal of leukocyte biology, 1999

View PDFchevron_right

Identification of STAT2 Serine 287 as a Novel Regulatory Phosphorylation Site in Type I Interferon-induced Cellular Responses

Ana Gamero, C. Barrero

Journal of Biological Chemistry, 2013

View PDFchevron_right

STAT3 and STAT5B are targets of two different signal pathways activated by hematopoietin receptors and control transcription via separate cytokine response

Karen Campos

Journal of Biological …, 1995

View PDFchevron_right

A Mutation in the SH2 Domain of STAT2 Prolongs Tyrosine Phosphorylation of STAT1 and Promotes Type I IFN-induced Apoptosis

Ana Gamero, Faruk Sheikh

Molecular Biology of the Cell, 2007

View PDFchevron_right

The Proximal Tyrosines of the Cytoplasmic Domain of the beta Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation. EVIDENCE THAT TWO Stat2 SITES ARE REQUIRED TO REACH A THRESHOLD OF INTERFERON alpha -INDUCED Stat2 TYROSINE ...

Regina Raz

Journal of Biological Chemistry, 1999

View PDFchevron_right

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

Michael Brown

Cell, 1998

View PDFchevron_right

Transcriptional Inhibition by Stat5

Li-yuan Yu-lee

Journal of Biological Chemistry, 1997

View PDFchevron_right

Isolation of Unique STAT5 Targets by Chromatin Immunoprecipitation-based Gene Identification

David Frank

Journal of Biological Chemistry, 2004

View PDFchevron_right

Cutting Edge: Selective Tyrosine Dephosphorylation of Interferon-Activated Nuclear STAT5 by the VHR Phosphatase

T. Mustelin

The Journal of Immunology, 2007

View PDFchevron_right

Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2V617F in mice

M. Betancur

Blood, 2012

View PDFchevron_right

Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons

Thomas Decker

EMBO reports, 2003

View PDFchevron_right

Functionally Distinct Isoforms of STAT5 Are Generated by Protein Processing

Mohammad Azam

Immunity, 1997

View PDFchevron_right

Stat1-independent induction of SOCS-3 by interferon-γ is mediated by sustained activation of Stat3 in mouse embryonic fibroblasts

Richard Enelow

Biochemical and Biophysical Research Communications, 2005

View PDFchevron_right

Stat5 as Hematopoietic Gatekeeper and Oncogene Upon Tyrosine Kinase-Induced Transformation

Marc Kerenyi

View PDFchevron_right

Interferon-α activates signal transducers and activators of transcription 5 and 6 in Daudi cells

Elizaveta Fasler-kan

1998

View PDFchevron_right

Colony-stimulating factors and interferon-γ activate a protein related to MGF-Stat 5 to cause formation of the differentiation-induced factor in myeloid cells

Andreas L Meinke

FEBS Letters, 1995

View PDFchevron_right

The Biological Functions of the Versatile Transcription Factors STAT3 and STAT5 and New Strategies for their Targeted Inhibition

Bernd Groner

Journal of Mammary Gland Biology and Neoplasia, 2006

View PDFchevron_right

Modulation of the activation status of Stat5a during LIF-induced differentiation of M1 myeloid leukemia cells

Roland Piekorz

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1998

View PDFchevron_right

Interleukin-3 signals through multiple isoforms of Stat5

C. Saris

The EMBO journal, 1995

View PDFchevron_right

Chromatin Dynamics of Gene Activation and Repression in Response to Interferon (IFN ) Reveal New Roles for Phosphorylated and Unphosphorylated Forms of the Transcription Factor STAT2

B. Testoni

Journal of Biological Chemistry, 2011

View PDFchevron_right

The Proximal Tyrosines of the Cytoplasmic Domain of the β Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation

Regina Raz

Journal of Biological Chemistry, 1999

View PDFchevron_right

A Sequence of the CIS Gene Promoter Interacts Preferentially with Two Associated STAT5A Dimers: a Distinct Biochemical Difference between STAT5A and STAT5B

Patrick Mayeux

1998

View PDFchevron_right

Constitutive STAT5 activation specifically cooperates with the loss of p53 function in B-cell lymphomagenesis

Hector Fernandez

Oncogene, 2006

View PDFchevron_right

Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

Stephan Teglund

Immunity, 1999

View PDFchevron_right

The antitumor effects of IFN-α are abrogated in a STAT1-deficient mouse

Gerard Abood

Journal of Clinical Investigation, 2003

View PDFchevron_right

STAT5a is required for eosinophil differentiation

Leo Koenderman

2002

View PDFchevron_right