Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons (original) (raw)
Identification of STAT2 Serine 287 as a Novel Regulatory Phosphorylation Site in Type I Interferon-induced Cellular Responses
Ana Gamero, C. Barrero
Journal of Biological Chemistry, 2013
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STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response and antiviral activity in the absence of STAT1
Joanna Wesoly, Balint Balint
Biochemical Journal, 2015
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Protein Kinase C-delta (PKC-delta ) Is Activated by Type I Interferons and Mediates Phosphorylation of Stat1 on Serine 727
Arshad Rahman
Journal of Biological Chemistry, 2002
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Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1
Paul Hertzog
PLoS Biology, 2010
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Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages
Ilkka Julkunen
Journal of Immunology, 1997
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The Stat1 Binding Motif of the Interferon-gamma Receptor Is Sufficient to Mediate Stat5 Activation and Its Repression by SOCS3
Thomas Decker
Journal of Biological Chemistry, 2001
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Cells Previously Desensitized to Type 1 Interferons Display Different Mechanisms of Activation of Stat-dependent Gene Expression from Naive Cells
Ana Gamero
Journal of Biological Chemistry, 2003
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A novel anti-viral role for STAT3 in IFN-α signalling responses
Nigel Stevenson
Cellular and molecular life sciences : CMLS, 2017
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The Proximal Tyrosines of the Cytoplasmic Domain of the beta Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation. EVIDENCE THAT TWO Stat2 SITES ARE REQUIRED TO REACH A THRESHOLD OF INTERFERON alpha -INDUCED Stat2 TYROSINE ...
Regina Raz
Journal of Biological Chemistry, 1999
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Activation of Different Stat5 Isoforms Contributes to Cell-Type- Restricted Signaling in Response to Interferons
Andreas L Meinke
1996
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Global changes in STAT target selection and transcription regulation upon interferon treatments
Paul Bertone
Genes & Development, 2005
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Chromatin Dynamics of Gene Activation and Repression in Response to Interferon (IFN ) Reveal New Roles for Phosphorylated and Unphosphorylated Forms of the Transcription Factor STAT2
B. Testoni
Journal of Biological Chemistry, 2011
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STAT2 Binding to the Interferon-α Receptor 2 Subunit is Not Required for Interferon-α Signaling
Abu Saleh
Journal of Biological …, 2002
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Stat2 Binding to the Interferon-alpha Receptor 2 Subunit Is Not Required for Interferon-alpha Signaling
abu saleh
Journal of Biological Chemistry, 2002
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Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency
Ariane Chapgier
Nature Genetics, 2003
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Impaired response to interferon-α/β and lethal viral disease in human STAT1 …
Ariane Chapgier
Nature genetics, 2003
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Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency
Pierre Eid
Nature genetics, 2003
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STAT1 is not dominant negative and is capable of contributing to IFN -dependent innate immunity
Christian Semper
Molecular and Cellular Biology, 2014
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STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling
Filipa Antunes
Nature Immunology, 2014
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Heterozygous Cell Models of STAT1 Gain-of-Function Reveal a Broad Spectrum of Interferon-Signature Gene Transcriptional Responses
Ori Scott
2020
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The Proximal Tyrosines of the Cytoplasmic Domain of the β Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation
Regina Raz
Journal of Biological Chemistry, 1999
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Inhibition of Stat1-mediated gene activation by PIAS1
chan whiting
Proceedings of the National Academy of Sciences, 1998
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CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response
Lars Dölken
Immunity, 2013
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Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR
Thomas Decker
The Journal of biological chemistry, 2001
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Stat1 and Stat2 but Not Stat3 Arbitrate Contradictory Growth Signals Elicited by Alpha/Beta Interferon in T Lymphocytes
Ramon Gimeno
Molecular and Cellular Biology, 2005
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The Rac1/p38 Mitogen-activated Protein Kinase Pathway Is Required for Interferon α-dependent Transcriptional Activation but Not Serine Phosphorylation of Stat Proteins
Dr. M. Shahab Uddin
Journal of Biological Chemistry, 2000
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