The Proximal Tyrosines of the Cytoplasmic Domain of the beta Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation. EVIDENCE THAT TWO Stat2 SITES ARE REQUIRED TO REACH A THRESHOLD OF INTERFERON alpha -INDUCED Stat2 TYROSINE ... (original ) (raw )The Proximal Tyrosines of the Cytoplasmic Domain of the β Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation
Regina Raz
Journal of Biological Chemistry, 1999
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STAT2 Binding to the Interferon-α Receptor 2 Subunit is Not Required for Interferon-α Signaling
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Journal of Biological …, 2002
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Stat2 Binding to the Interferon-alpha Receptor 2 Subunit Is Not Required for Interferon-alpha Signaling
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Journal of Biological Chemistry, 2002
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Affinity of Stat2 for the Subunits of the Interferon Alpha Receptor
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Identification of STAT2 Serine 287 as a Novel Regulatory Phosphorylation Site in Type I Interferon-induced Cellular Responses
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Olli Silvennoinen
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Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages
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1998
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Masahiko Hibi
Oncogene, 1997
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The WD Motif-containing Protein Receptor for Activated Protein Kinase C (RACK1) Is Required for Recruitment and Activation of Signal Transducer and Activator of Transcription 1 through the Type I Interferon Receptor
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Journal of Biological Chemistry, 2001
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Journal of Biological Chemistry, 2007
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EMBO reports, 2003
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Dominant Negative Stat3 Mutant Inhibits Interleukin-6-induced Jak-STAT Signal Transduction
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Journal of Biological Chemistry, 1996
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Definition of the Interferon-α Receptor-binding Domain on the TYK2 Kinase
Flavia Piazza
Journal of Biological Chemistry, 1998
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Specific Contribution of Tyk2 JH Regions to the Binding and the Expression of the Interferon alpha /beta Receptor Component IFNAR1
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Activation of the Jak-Stat Pathway in Cells That Exhibit Selective Sensitivity to the Antiviral Effects of IFN-beta Compared with IFN-alpha
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Palmitoylation of Interferon-(IFN-) Receptor Subunit IFNAR1 Is Required for the Activation of Stat1 and Stat2 by IFN
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Protein Kinase C-delta (PKC-delta ) Is Activated by Type I Interferons and Mediates Phosphorylation of Stat1 on Serine 727
Arshad Rahman
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Sonja Schmid
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Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-γ, but not IFN-α, signaling
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Palmitoylation of Interferon-α (IFN-α) Receptor Subunit IFNAR1 Is Required for the Activation of Stat1 and Stat2 by IFN-α
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