Selective drug transport and P-glycoprotein activity in an in vitro blood-brain barrier model (original) (raw)

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood–brain barrier model for drug uptake and transport studies

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IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening

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Verapamil P-glycoprotein Transport across the Rat Blood-Brain Barrier: Cyclosporine, a Concentration Inhibition Analysis, and Comparison with Human Data

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Quantitative assessment of P-glycoprotein function in the rat blood–brain barrier by distribution volume of [11C]verapamil measured with PET

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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vitro to in vivo prediction of P-glycoprotein based drug interactions at the human and rodent blood-brain barrier. Drug Metab Dispos

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A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

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Similar molecular descriptors determine the in vitro drug permeability in endothelial and epithelial cells

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Drug targeting to brain: A systematic approach to study the factors, parameters and approaches for prediction of permeability of drugs across BBB

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In vivo saturation of the transport of vinblastine and colchicine by P-glycoprotein at the rat blood-brain barrier

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In-vitro blood-brain barrier models for drug screening and permeation studies: an overview

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Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood–Brain Barrier

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The Role of Size and Charge for Blood–Brain Barrier Permeation of Drugs and Fatty Acids

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Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats

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Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat

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Effect of Tacrolimus on Activity and Expression of P-Glycoprotein and ATP-Binding Cassette Transporter A5 (ABCA5) Proteins in Hematoencephalic Barrier Cells

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