Synthesis of conformationally constrained potential inhibitors of mammalian metalloproteinases
Andrew Griffin
Bioorganic & Medicinal Chemistry Letters, 1997
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7-Oxanorbornane and Norbornane Mimics of a Distortedβ-D-Mannopyranoside: Synthesis and Evaluation asβ-Mannosidase Inhibitors
Stephan Buser
Helvetica Chimica Acta, 2005
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De Novo Design, Synthesis, and In Vitro Evaluation of a New Class of Nonpeptidic Inhibitors of the Malarial Enzyme Plasmepsin II
Bur Han
Chembiochem, 2002
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Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor
Bernard Roques
Bioorganic & Medicinal Chemistry Letters, 1999
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The Most Potent Organophosphorus Inhibitors of Leucine Aminopeptidase. Structure-Based Design, Chemistry, and Activity
Pawel Kafarski
Journal of Medicinal Chemistry, 2003
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High-affinity inhibitors of Zymomonas mobilis tRNA–guanine transglycosylase through convergent optimization
Gerhard Klebe
Acta Crystallographica Section D Biological Crystallography, 2013
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Design and synthesis of carbohydrate-based inhibitors of protein—carbohydrate interactions
Mark Von Itzstein
Current Opinion in Structural Biology, 1996
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Investigation of Subsite Preferences in Aminopeptidase A (EC 3.4.11.7) Led to the Design of the First Highly Potent and Selective Inhibitors of This Enzyme
Bernard Roques
Journal of Medicinal Chemistry, 1999
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Crystallographic studies on N-azidoacetyl-β-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-β-d-glucopyranosylamine
Evangelia Chrysina
Bioorganic & Medicinal Chemistry, 2006
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Synthesis and evaluation of eight aminodeoxy trisaccharide inhibitors for N-acetylglucosaminyltransferase-V
Pu-Ping Lu
Carbohydrate Research, 1997
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An approach to design, in silico predictions and molecular docking studies of 1,3,4-oxadiazolyl sulphonamides as possible inhibitors of bacterial Mur enzymes, the amino acid ligases in peptidoglycan synthesis
haseena banu
Journal of Advanced Research in Biotechnology, 2017
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Potent inhibition of glycogen phosphorylase by a spirohydantoin of glucopyranose: First pyranose analogues of hydantocidin
Kimberly Watson
Tetrahedron Letters, 1995
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Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S2 pocket
Brian Owens
Bioorganic & Medicinal Chemistry Letters, 1999
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Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition ‡
Rose Stiffin
Biochemistry, 2008
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Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein
Andreas Kohl, Markus Grütter
Structure, 2005
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Synthesis and evaluation of dual site inhibitors of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase
Emily Parker
Bioorganic & Medicinal Chemistry Letters, 2011
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Medicinal Chemistry Studies Applied to Protein Targets
Marcus Scotti
Current Protein & Peptide Science, 2019
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Structurally unique recombinant Kazal-type proteinase inhibitor retains activity when terminally extended and glycosylated
František Sehnal
Protein Expression and Purification, 2005
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Structural characterization of inhibitors with selectivity against members of a homologous enzyme family
Ronald Viola
2012
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Mechanism-Based Inhibitors for the Inactivation of the Bacterial Phosphotriesterase
Leisha Mullins
Biochemistry, 1997
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Structural Insight into the Stereoselective Inhibition of MMP-8 by Enantiomeric Sulfonamide Phosphonates
Giorgio Pochetti
Journal of Medicinal Chemistry, 2006
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Synthesis, enzyme kinetics and computational evaluation of N-(β-D-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors
Mónika Polyák
Bioorganic & medicinal chemistry, 2013
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Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors
Siquan Sun, Scott Bembenek
Bioorganic & Medicinal Chemistry Letters, 2010
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The reaction mechanism of type I phosphomannose isomerases: New information from inhibition and polarizable molecular mechanics studies
Jean-Philip Piquemal
2011
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Synthesis of 1,5-dideoxy-3-O-(α-D-mannopyranosyl)-1,5-imino-D-mannitol and 1,5-dideoxy-3-O-(α-D-glucopyranosyl)-1,5-imino-D-mannitol: Powerful inhibitors of endomannosidase
Raymond Dwek
Tetrahedron: Asymmetry, 1993
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In silico study of MMP inhibition
Erika Bourguet
Organic & Biomolecular Chemistry, 2009
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Arylamidase activity of neutral proteinase from Saccharomonospora canescens. Comparison with other Zn-proteinases that exhibit the same activity
pavlina dolashka
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Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements
Siquan Sun, Scott Bembenek
Bioorganic & Medicinal Chemistry Letters, 2009
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The discovery of anthranilic acid-based mmp inhibitors. Part 3: incorporation of basic amines
Robert Powers
Bioorganic & Medicinal Chemistry Letters, 2001
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Structure-based design of novel inhibitors of 3-deoxy-D-manno-octulosonate 8-phosphate synthase
Sylvain Petek
Drug design and discovery, 2003
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Structural analogues of reactive intermediates as inhibitors of glucosamine-6-phosphate synthase and phosphoglucose isomerase
Marek WOJCIECHOWSKI
Archives of Biochemistry and Biophysics, 2006
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Design, synthesis, and structure–activity relationship studies of N-arylsulfonyl morpholines as γ-secretase inhibitors
ahmed ib ahmed
Bioorganic & Medicinal Chemistry Letters, 2010
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Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: Synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods
Katalin E. Kövér
Bioorganic & Medicinal Chemistry, 2014
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