Mechanism of 2-chloroadenosine toxicity to PC3 cell line (original) (raw)
Differential involvement of reactive oxygen species and nucleoside transporters in cytotoxicity induced by two adenosine analogues in human prostate cancer cells
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The Prostate, 2009
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Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3
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Deoxynucleotide pool depletion and sustained inhibition of ribonucleotide reductase and DNA synthesis after treatment of human lymphoblastoid cells with 2-chloro-9 …
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Proceedings of The National Academy of Sciences, 1998
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Adenosine stimulates DNA fragmentation in human thymocytes by Ca(2+)-mediated mechanisms
Z. Szondy
The Biochemical journal, 1994
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Enhanced levels of cyclic AMP, adenosine(5′)tetraphospo(5′)adenosine and nucleoside 5′-triphosphates in mouse leukemia P388/D1 after treatment with cis-diamminedichloroplatinum(II)
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Biochemical Pharmacology, 1991
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2000
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2-Chloroadenosine but not adenosine induces apoptosis in rheumatoid fibroblasts independently of cell surface adenosine receptor signalling
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Potentiation of CB 1954 cytotoxicity by reduced pyridine nucleotides in human tumour cells by stimulation of DT diaphorase activity
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Etoposide-induced PC12 cell death: apoptotic morphology without oligonucleosomal DNA fragmentation or dependency upon de novo protein synthesis
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Molecular Brain Research, 1997
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Correlation of Enhanced 6-Mercaptopurine Cytotoxicity with Increased Phosphoribosylpyrophosphate Levels in Chinese Hamster Ovary Cells Treated with 3-Aminobenzamide
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Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity
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Cell cycle effect on the activity of deoxynucleoside analogue metabolising enzymes
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Induction of Cell Death, DNA Strand Breaks, and Cell Cycle Arrest in DU145 Human Prostate Carcinoma Cell Line by Benzo[a]pyrene and Benzo[a]pyrene-7,8-diol-9,10-epoxide
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In vitro competition between adenosine(5')tetraphospho(5')adenosine and deoxyribonucleic acid in the reaction with diamminedichloroplatinum(II)
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European Journal of Biochemistry, 1986
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Cytotoxicity of N6-substituted adenosine analogs to cultured trophoblastic tumor cells
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Biochemical Pharmacology, 1979
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Diadenosine 5′,5′′′-P1,P4-tetraphosphate (AP4A) levels under various proliferative and cytotoxic conditions in several mammalian cell types
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Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway
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Journal of Cancer Research and Clinical Oncology, 2011
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Studies on the mechanism of cytotoxicity of 3?-deoxyadenosine N1-oxide in different strains of Ehrlich ascites tumor cells
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Cancer Chemotherapy and Pharmacology, 1987
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Torriglia, A. et al. Differential involvement of DNases in HeLa cell apoptosis induced by etoposide and long-term culture. Cell Death Differ. 6, 234-244
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Potentiation of Etoposide-induced DNA Damage by Calcium Antagonists in L1210 Cells in Vitro
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Cancer Research, 1984
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DNA reactivity and in vitro cytotoxicity of the novel antitumor agent 1,5,2,4-dioxadithiepane-2,2,4,4-tetraoxide (NSC-348948) in human embryo cells
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