Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors (original) (raw)

Activation of a GTP-Binding Protein and a GTP-Binding-Protein-Coupled Receptor Kinase (beta-Adrenergic-Receptor Kinase-1) by a Muscarinic Receptor m2 Mutant Lacking Phosphorylation Sites

T. Haga

European Journal of Biochemistry, 1994

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Reconstitution of functional muscarinic receptors by co-expression of amino- and carboxyl-terminal receptor fragments

Zvi Vogel

FEBS Letters, 1993

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Differential Modification of the Interaction of Cardiac Muscarinic Cholinergic and β-Adrenergic Receptors with a Guanine Nucleotide Binding Component(s).

McHardy Smith

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Binding characteristics of the muscarinic receptor subtype of the NG108-15 cell line

Anton Michel

Naunyn-schmiedebergs Archives of Pharmacology, 1989

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Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors

Vladimír Doležal

Scientific Reports

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Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors

Vladimír Doležal

PLoS ONE, 2011

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Agonist binding to M1 muscarinic receptors is sensitive to guanine nucleotides

nick palermo

European Journal of Pharmacology: Molecular Pharmacology, 1989

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Coexpression of N- and C- terminal muscarinic receptor domains results in functional receptors

Zvi Vogel

Life Sciences, 1993

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Cooperativity and Oligomeric Status of Cardiac Muscarinic Cholinergic Receptors †

Paul Park

Biochemistry, 2002

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Characterization of M2 muscarinic receptor activation of different G protein subtypes

Karl Åkerman

Neurochemistry International, 2004

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Activation by G protein βγ subunits of β-adrenergic and muscarinic receptor kinase

T. Haga

Journal of Biological Chemistry

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The presence of an M4 subtype muscarinic receptor in the bovine adrenal medulla revealed by mRNA and receptor binding analyses

esam abdallah

European Journal of Pharmacology: Molecular Pharmacology, 1991

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Muscarinic receptor subtypes in bovine adrenal medulla

Jose Aguilar

Biochemical Pharmacology, 1986

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Quasi-irreversible binding of agonist to β-adrenoceptors and formation of non-dissociating receptor–Gs complex in the absence of guanine nucleotides

Ongun Onaran

European Journal of Pharmacology, 2001

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Activation and allosteric modulation of a muscarinic acetylcholine receptor

Peter Gmeiner

Nature, 2013

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Haga, K., Haga, T. & Ichiyama, A. Reconstitution of the muscarinic acetylcholine receptor. Guanine nucleotide-sensitive high affinity binding of agonists to purified muscarinic receptors reconstituted with GTP-binding proteins (Gi and Go). J. Biol. Chem. 261, 10133-10140

T. Haga

Journal of Biological Chemistry

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Regulation of muscarinic receptor binding by guanine nucleotides and N-ethylmaleimide

Frederick Ehlert

Journal of supramolecular structure, 1980

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α-Helical distorting substitutions disrupt coupling between m3 muscarinic receptor and G proteins

D Clapham

FEBS Letters, 1993

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Muscarinic Receptors—Characterization, coupling and function

Malcolm Caulfield

Pharmacology & Therapeutics, 1993

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Secretory and radioligand binding studies on muscarinic receptors in bovine and feline chromaffin cells

Ricardo Borges

The Journal of Physiology, 1989

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The Human Muscarinic Receptor Couples to GαI3 Via Catalytic Collision

Daniel Yakubovich

Biophysical Journal, 2010

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Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of theα2A-adrenoceptor

Liisa Kanerva

British Journal of Pharmacology, 2003

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Effective Information Transfer from the α1b-Adrenoceptor to Gα11 Requires Both β/γ Interactions and an Aromatic Group Four Amino Acids from the C Terminus of the G Protein

John Pediani

Journal of Biological Chemistry, 2002

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Coupling of subtypes of the muscarinic receptor to adenylate cyclase in corpus striatum and heart

Frederick Ehlert

Journal of Pharmacology and Experimental Therapeutics

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Evidence for Adenosine/Dopamine Receptor Interactions:: Indications for Heteromerization

Michele Zoli

…, 2000

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Phosphorylation of muscarinic receptors: regulation by G proteins

T. Haga

Life Sciences, 1993

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Temperature effect on the detection of muscarinic receptor-G protein interactions in ligand binding assays

Robert Aronstam

Biochemical Pharmacology, 1988

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G-protein mediates voltage regulation of agonist binding to muscarinic receptors: effects on receptor-sodium channel interaction

Malka Cohen-Armon

Biochemistry, 1988

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Assessment of mechanistic proposals for the binding of agonists to cardiac muscarinic receptors

Michael Sole

Biochemistry, 1986

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Full and Partial Agonists of Muscarinic M3 Receptors Reveal Single and Oscillatory Ca2+ Responses by β2-Adrenoceptors

Gary Willars

The Journal of Pharmacology and Experimental Therapeutics, 2009

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Evidence for a Tandem Two-site Model of Ligand Binding to Muscarinic Acetylcholine Receptors

Jan Jakubik

Journal of Biological Chemistry, 2000

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Full and Partial Agonists of Muscarinic M3 Receptors Reveal Single and Oscillatory Ca2+ Responses by 2-Adrenoceptors

Gary Willars

Journal of Pharmacology and Experimental Therapeutics, 2009

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The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the ß 1 -adrenergic receptor to G s

Hassan Hajjhussein

Journal of Receptors and Signal Transduction, 2013

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Binding characteristics and functional G protein coupling of muscarinic acetylcholine receptors in rat duodenum smooth muscle membranes

Martin Schnittler

Naunyn-Schmiedeberg's Archives of Pharmacology, 1992

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