Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors (original ) (raw )Activation of a GTP-Binding Protein and a GTP-Binding-Protein-Coupled Receptor Kinase (beta-Adrenergic-Receptor Kinase-1) by a Muscarinic Receptor m2 Mutant Lacking Phosphorylation Sites
T. Haga
European Journal of Biochemistry, 1994
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Reconstitution of functional muscarinic receptors by co-expression of amino- and carboxyl-terminal receptor fragments
Zvi Vogel
FEBS Letters, 1993
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Differential Modification of the Interaction of Cardiac Muscarinic Cholinergic and β-Adrenergic Receptors with a Guanine Nucleotide Binding Component(s).
McHardy Smith
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Binding characteristics of the muscarinic receptor subtype of the NG108-15 cell line
Anton Michel
Naunyn-schmiedebergs Archives of Pharmacology, 1989
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Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors
Vladimír Doležal
Scientific Reports
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Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors
Vladimír Doležal
PLoS ONE, 2011
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Agonist binding to M1 muscarinic receptors is sensitive to guanine nucleotides
nick palermo
European Journal of Pharmacology: Molecular Pharmacology, 1989
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Coexpression of N- and C- terminal muscarinic receptor domains results in functional receptors
Zvi Vogel
Life Sciences, 1993
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Cooperativity and Oligomeric Status of Cardiac Muscarinic Cholinergic Receptors †
Paul Park
Biochemistry, 2002
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Characterization of M2 muscarinic receptor activation of different G protein subtypes
Karl Åkerman
Neurochemistry International, 2004
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Activation by G protein βγ subunits of β-adrenergic and muscarinic receptor kinase
T. Haga
Journal of Biological Chemistry
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The presence of an M4 subtype muscarinic receptor in the bovine adrenal medulla revealed by mRNA and receptor binding analyses
esam abdallah
European Journal of Pharmacology: Molecular Pharmacology, 1991
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Muscarinic receptor subtypes in bovine adrenal medulla
Jose Aguilar
Biochemical Pharmacology, 1986
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Quasi-irreversible binding of agonist to β-adrenoceptors and formation of non-dissociating receptor–Gs complex in the absence of guanine nucleotides
Ongun Onaran
European Journal of Pharmacology, 2001
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Activation and allosteric modulation of a muscarinic acetylcholine receptor
Peter Gmeiner
Nature, 2013
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Haga, K., Haga, T. & Ichiyama, A. Reconstitution of the muscarinic acetylcholine receptor. Guanine nucleotide-sensitive high affinity binding of agonists to purified muscarinic receptors reconstituted with GTP-binding proteins (Gi and Go). J. Biol. Chem. 261, 10133-10140
T. Haga
Journal of Biological Chemistry
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Regulation of muscarinic receptor binding by guanine nucleotides and N-ethylmaleimide
Frederick Ehlert
Journal of supramolecular structure, 1980
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α-Helical distorting substitutions disrupt coupling between m3 muscarinic receptor and G proteins
D Clapham
FEBS Letters, 1993
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Muscarinic Receptors—Characterization, coupling and function
Malcolm Caulfield
Pharmacology & Therapeutics, 1993
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Secretory and radioligand binding studies on muscarinic receptors in bovine and feline chromaffin cells
Ricardo Borges
The Journal of Physiology, 1989
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The Human Muscarinic Receptor Couples to GαI3 Via Catalytic Collision
Daniel Yakubovich
Biophysical Journal, 2010
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Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of theα 2A -adrenoceptor
Liisa Kanerva
British Journal of Pharmacology, 2003
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Effective Information Transfer from the α1b-Adrenoceptor to Gα11 Requires Both β/γ Interactions and an Aromatic Group Four Amino Acids from the C Terminus of the G Protein
John Pediani
Journal of Biological Chemistry, 2002
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Coupling of subtypes of the muscarinic receptor to adenylate cyclase in corpus striatum and heart
Frederick Ehlert
Journal of Pharmacology and Experimental Therapeutics
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Evidence for Adenosine/Dopamine Receptor Interactions:: Indications for Heteromerization
Michele Zoli
…, 2000
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Phosphorylation of muscarinic receptors: regulation by G proteins
T. Haga
Life Sciences, 1993
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Temperature effect on the detection of muscarinic receptor-G protein interactions in ligand binding assays
Robert Aronstam
Biochemical Pharmacology, 1988
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G-protein mediates voltage regulation of agonist binding to muscarinic receptors: effects on receptor-sodium channel interaction
Malka Cohen-Armon
Biochemistry, 1988
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Assessment of mechanistic proposals for the binding of agonists to cardiac muscarinic receptors
Michael Sole
Biochemistry, 1986
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Full and Partial Agonists of Muscarinic M3 Receptors Reveal Single and Oscillatory Ca2+ Responses by β2-Adrenoceptors
Gary Willars
The Journal of Pharmacology and Experimental Therapeutics, 2009
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Evidence for a Tandem Two-site Model of Ligand Binding to Muscarinic Acetylcholine Receptors
Jan Jakubik
Journal of Biological Chemistry, 2000
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Full and Partial Agonists of Muscarinic M3 Receptors Reveal Single and Oscillatory Ca2+ Responses by 2-Adrenoceptors
Gary Willars
Journal of Pharmacology and Experimental Therapeutics, 2009
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The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the ß 1 -adrenergic receptor to G s
Hassan Hajjhussein
Journal of Receptors and Signal Transduction, 2013
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Binding characteristics and functional G protein coupling of muscarinic acetylcholine receptors in rat duodenum smooth muscle membranes
Martin Schnittler
Naunyn-Schmiedeberg's Archives of Pharmacology, 1992
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