SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy
Juan Ferrario
Frontiers in Bioengineering and Biotechnology
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Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy
Magdalena De León
Brain, 2021
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Regulation of Alternative Splicing of Human Tau Exon 10 by Phosphorylation of Splicing Factors
Thomas Giannakouros
Molecular and Cellular Neuroscience, 2001
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Tau with three and four microtubule-binding repeats in human brain of Alzheimer's disease and frontotemporal dementia
Nenad Bogdanovic
Neurobiology of Aging, 2000
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Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders
Max Holzer
Molecular Brain Research, 1999
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Splicing factor SC35 promotes tau expression through stabilization of its mRNA
Khalid Iqbal
FEBS Letters, 2011
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No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer’s disease brain
Jennifer Osetek
Acta Neuropathologica, 2006
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5' Splice Site Mutations in tau Associated with the Inherited Dementia FTDP-17 Affect a Stem-Loop Structure That Regulates Alternative Splicing of Exon 10
Jennifer Adamson
Journal of Biological Chemistry, 1999
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Amyloid-β peptide alteration of tau exon-10 splicing via the GSK3β-SC35 pathway
cy hsu
Neurobiology of Disease, 2010
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Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration
Mary Jordan
Molecular Biology of the Cell, 2004
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Tau mRNA Metabolism in Neurodegenerative Diseases: A Tangle Journey
Franck Martin
Biomedicines
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SRp54 (SFRS11), a Regulator for Tau Exon 10 Alternative Splicing Identified by An Expression Cloning Strategy
David Kuo
Molecular and cellular …, 2006
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Tau Alternative Splicing and Frontotemporal Dementia
Rongqiao He
Alzheimer Disease & Associated Disorders, 2005
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The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology
Jessica Childs-Disney
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FTDP-17 Mutations Compromise the Ability of Tau to Regulate Microtubule Dynamics in Cells
Mary Jordan
Journal of Biological Chemistry, 2006
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Aberrant Splicing of tau Pre-mRNA Caused by Intronic Mutations Associated with the Inherited Dementia Frontotemporal Dementia with Parkinsonism Linked to Chromosome 17
Jocelyn Cote
Molecular and Cellular Biology, 2000
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Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A
Khalid Iqbal
Nucleic Acids Research, 2011
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Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains
Jennifer Osetek
Acta Neuropathologica, 2007
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SR protein 9G8 modulates splicing of tau exon 10 via its proximal downstream intron, a clustering region for frontotemporal dementia mutations
lei gao
Molecular and Cellular Neuroscience, 2007
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RNA editing of microtubule-associated protein tau circular RNAs promotes their translation and tau tangle formation
Giorgi Margvelani
Nucleic Acids Research
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Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
Yann Verdier
Scientific Reports, 2015
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Cyclic AMP-dependent Protein Kinase Regulates the Alternative Splicing of Tau Exon 10: A MECHANISM INVOLVED IN TAU PATHOLOGYOFALZHEIMER DISEASE
Khalid Iqbal
The Journal of Biological Chemistry, 2011
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Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17
Luca Varani
Proceedings of the National Academy of Sciences, 1999
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Alternative Splicing of Amino-Terminal Tau mRNA in Rat Spinal Cord during Development and Following Axonal Injury
Nancy Muma
Experimental Neurology, 2001
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The Tau N279K Exon 10 Splicing Mutation Recapitulates Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Tauopathy in a Mouse Model
Michael Vitek
Journal of Neuroscience, 2007
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The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease
Christine Hulette
Journal of Neurochemistry, 2006
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Analysis of tauopathies with transgenic mice
Dennis Dickson
Trends in Molecular Medicine, 2001
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Tau modulates mRNA transcription, alternative polyadenylation profiles of hnRNPs, chromatin remodeling and spliceosome complexes
Stephanie Garcia
2021
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Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements
Thomas Bird
Proceedings of the National Academy of Sciences, 1999
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Tau-based treatment strategies in neurodegenerative diseases
Anja Schneider
Neurotherapeutics, 2008
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MicroRNAs and the Regulation of Tau Metabolism
Luc Buée
2012
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Regulation of neuronal mRNA splicing and Tau isoform ratio by ATXN3 through deubiquitylation of splicing factors
Bruno Almeida
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