FTDP-17 Mutations Compromise the Ability of Tau to Regulate Microtubule Dynamics in Cells (original) (raw)
Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration
Mary Jordan
Molecular Biology of the Cell, 2004
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Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders
Max Holzer
Molecular Brain Research, 1999
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Three- and Four-repeat Tau Regulate the Dynamic Instability of Two Distinct Microtubule Subpopulations in Qualitatively Different Manners
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Journal of Biological Chemistry, 2005
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Microtubule-dependent Oligomerization of Tau: IMPLICATIONS FOR PHYSIOLOGICAL TAU FUNCTION AND TAUOPATHIES
victoria makrides
Journal of Biological Chemistry, 2003
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Jonathan Samuel
Proceedings of the National Academy of Sciences, 2003
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Yann Verdier
Scientific Reports, 2015
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Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects
Bernard Schneider
Scientific reports, 2017
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Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability
Frida Kleiman
Frontiers in cellular neuroscience, 2018
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Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects
Caroline Smet-Nocca
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Juan Ferrario
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Nenad Bogdanovic
Neurobiology of Aging, 2000
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Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies
Abdala Ussif
Molecular and Cellular Neuroscience, 2017
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Oligomerization of the Microtubule Associated Protein Tau is Mediated by its N-Terminal Sequences: Implications for Normal and Pathological Tau Action
Srinivasan Ramachandran
Journal of neurochemistry, 2016
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Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy
Magdalena De León
Brain, 2021
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The Tau N279K Exon 10 Splicing Mutation Recapitulates Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Tauopathy in a Mouse Model
Michael Vitek
Journal of Neuroscience, 2007
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SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy
Juan Ferrario
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N-terminal truncation of microtubule associated protein tau dysregulates its cellular localization
Barbara Salingova
Journal of Alzheimer's disease : JAD, 2015
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Tau mRNA Metabolism in Neurodegenerative Diseases: A Tangle Journey
Franck Martin
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Tau protein in neurodegenerative diseases - a review
simona bondari
2017
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The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology
Jessica Childs-Disney
PLOS ONE
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Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM)
Merce Lliberia
Mechanisms of Ageing and Development, 2005
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FTDP-17 Mutations in Tau Alter the Regulation of Microtubule Dynamics
Arnab Bhattacharya
Journal of Biological …, 2008
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Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17
G. Varani
Proceedings of the National Academy of Sciences, 1999
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Familial FTDP-17 Missense Mutations Inhibit Microtubule Assembly-promoting Activity of Tau by Increasing Phosphorylation at Ser202 in Vitro
Hamid Yaqoob Qureshi
Journal of Biological Chemistry, 2009
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Vasudevaraju Padmaraju
Neurochemistry International, 2010
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Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau
Lidia Bakota
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Anja Schneider
Neurotherapeutics, 2008
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Anna Mietelska
2014
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Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction
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International Journal of Molecular Sciences, 2014
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Systematic Identification of Tubulin-interacting Fragments of the Microtubule-associated Protein Tau Leads to a Highly Efficient Promoter of Microtubule Assembly
Guy LIPPENS
Journal of Biological Chemistry, 2011
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Nuclear face of Tau: an inside player in neurodegeneration
N. Y.
Acta Neuropathologica Communications, 2023
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Disruption of microtubule network by Alzheimer abnormally hyperphosphorylated tau
Bin Li
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Brief update on different roles of tau in neurodegeneration
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