The MTHFR 677 C ---->T genotype modifies the relation of folate intake and status with plasma homocysteine in middle-aged and elderly people (original ) (raw )5,10-Methylenetetrahydrofolate reductase genotype determines the plasma homocysteine-lowering effect of supplementation with 5-methyltetrahydrofolate or folic acid in healthy young women
Anja Bohlmann
The American Journal of Clinical Nutrition, 2002
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Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women
Conrad Wagner
The Journal of nutrition, 2005
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Folate and homocysteine phenotypes: Comparative findings using research and clinical laboratory data
Alexander Whitehead
2009
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Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
Paul Jacques
Circulation, 1996
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MTHFR 677C->T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation
Thomas Yang
American Journal of Clinical Nutrition, 2011
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A folate-rich diet is as effective as folic acid from supplements in decreasing plasma homocysteine concentrations
Daniel Grinberg
International Journal of Medical Sciences, 2000
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Homocysteine and Folate Status in an Era of Folic Acid Fortification: Balancing Benefits, Risks, and B-vitamins
Per Magne Ueland
Clinical Chemistry, 2008
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Optimization of dietary folate or low-dose folic acid supplements lower homocysteine but do not enhance endothelial function in healthy adults, irrespective of the methylenetetrahydrofolate reductase (C677T) genotype
Ian McDowell
Journal of the American College of Cardiology, 2001
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Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population
Charles Halsted
The American journal of clinical nutrition, 2006
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Homocysteine Lowering by Folate-Rich Diet or Pharmacological Supplementations in Subjects with Moderate Hyperhomocysteinemia
Angelo Minucci , Licia Iacoviello , Aida Turrini
Nutrients, 2013
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The impact of MTHFR 677 C/T genotypes on folate status markers: a meta-analysis of folic acid intervention studies
Helen Naug
European journal of nutrition, 2015
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The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study
Tony Dowell
European Journal of Clinical Nutrition, 1998
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Assessment of three levels of folic acid on serum folate and plasma homocysteine: a randomised placebo-controlled double-blind dietary intervention trial
Wendy Riddell
European Journal of Clinical Nutrition, 2002
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Assessment of Folate Status: Measurement of Homocysteine versus Vitamin B12 and Folate
dalila naimi
Pteridines, 2003
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Folate intake, lifestyle factors, and homocysteine concentrations in younger and older women
Lars Ovesen
The American Journal of Clinical Nutrition, 2000
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Supplementation with [6S]-5-methyltetrahydrofolate or folic acid equally reduces serum homocysteine concentrations in older adults
Ewa Sicińska
International Journal of Food Sciences and Nutrition, 2017
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Plasma homocysteine, a risk factor for cardiovascular disease, is lowered by physiological doses of folic acid
Mary Ward
QJM, 1997
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Randomized Trial of Folic Acid Supplementation and Serum Homocysteine Levels
John Scott
Archives of Internal Medicine, 2001
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5,10-methylenetetrahydrofolate reductase common mutations, folate status and plasma homocysteine in healthy French adults of the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) cohort
Khalil Rabhi
British Journal of Nutrition, 2000
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The effect of folic acid supplementation on plasma homocysteine in an elderly population
Michael Golden
QJM, 2002
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Effects of Riboflavin and Folic Acid Supplementation on Plasma Homocysteine Levels in Healthy Subjects
Joseph Su
The American Journal of the Medical Sciences, 2006
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Long-term Effects of Folic Acid Fortification and B-vitamin Supplementation on Total Folate, Homocysteine, Methylmalonic Acid and Cobalamin in Older Adults
Angeles Colin Garcia
Canadian Journal of Public Health, 2008
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Effect of multivitamins on plasma homocysteine in patients with the 5,10 methylenetetrahydrofolate reductase C677T homozygous state
Elena Pacella
Molecular Medicine Reports, 2013
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The effect of folic acid fortification on plasma folate and total homocysteine concentrations
Andrew Bostom
1999
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Response of serum and red blood cell folate concentrations to folic acid supplementation depends on methylenetetrahydrofolate reductase C677T genotype: Results from a crossover trial
Shirley Beresford
Molecular Nutrition & Food Research, 2013
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Folate, Vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center
Erich de Paula , Luis Bittar
Nutrition Journal, 2015
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Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials
Geraldine Cuskelly
2005
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Plasma homocysteine concentrations in Greek children are influenced by an interaction between the methylenetetrahydrofolate reductase C677T genotype and folate status
Antonis Zampelas
The Journal of nutrition, 2005
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G1793A polymorphisms in the methyl- enetetrahydrofolate gene: Effect of folic acid on homocysteine levels
Sandra Melo
Molecular Nutrition & Food Research, 2006
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Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort
Paul Jacques
2003
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Choline Intake, Plasma Riboflavin, and the Phosphatidylethanolamine N-Methyltransferase G5465A Genotype Predict Plasma Homocysteine in Folate-Deplete Mexican-American Men with the Methylenetetrahydrofolate Reductase 677TT Genotype
Claudia Solis
Journal of Nutrition, 2009
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Total plasma homocysteine, folate, and vitamin b12 status in healthy Iranian adults: the Tehran homocysteine survey (2003–2004)/a cross–sectional population based study
Fatemeh Bandarian
2006
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