The MTHFR 677 C ---->T genotype modifies the relation of folate intake and status with plasma homocysteine in middle-aged and elderly people (original) (raw)

5,10-Methylenetetrahydrofolate reductase genotype determines the plasma homocysteine-lowering effect of supplementation with 5-methyltetrahydrofolate or folic acid in healthy young women

Anja Bohlmann

The American Journal of Clinical Nutrition, 2002

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Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women

Conrad Wagner

The Journal of nutrition, 2005

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Folate and homocysteine phenotypes: Comparative findings using research and clinical laboratory data

Alexander Whitehead

2009

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Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations

Paul Jacques

Circulation, 1996

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MTHFR 677C->T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation

Thomas Yang

American Journal of Clinical Nutrition, 2011

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A folate-rich diet is as effective as folic acid from supplements in decreasing plasma homocysteine concentrations

Daniel Grinberg

International Journal of Medical Sciences, 2000

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Homocysteine and Folate Status in an Era of Folic Acid Fortification: Balancing Benefits, Risks, and B-vitamins

Per Magne Ueland

Clinical Chemistry, 2008

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Optimization of dietary folate or low-dose folic acid supplements lower homocysteine but do not enhance endothelial function in healthy adults, irrespective of the methylenetetrahydrofolate reductase (C677T) genotype

Ian McDowell

Journal of the American College of Cardiology, 2001

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Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population

Charles Halsted

The American journal of clinical nutrition, 2006

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Homocysteine Lowering by Folate-Rich Diet or Pharmacological Supplementations in Subjects with Moderate Hyperhomocysteinemia

Angelo Minucci, Licia Iacoviello, Aida Turrini

Nutrients, 2013

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The impact of MTHFR 677 C/T genotypes on folate status markers: a meta-analysis of folic acid intervention studies

Helen Naug

European journal of nutrition, 2015

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The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study

Tony Dowell

European Journal of Clinical Nutrition, 1998

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Assessment of three levels of folic acid on serum folate and plasma homocysteine: a randomised placebo-controlled double-blind dietary intervention trial

Wendy Riddell

European Journal of Clinical Nutrition, 2002

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Assessment of Folate Status: Measurement of Homocysteine versus Vitamin B12 and Folate

dalila naimi

Pteridines, 2003

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Folate intake, lifestyle factors, and homocysteine concentrations in younger and older women

Lars Ovesen

The American Journal of Clinical Nutrition, 2000

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Supplementation with [6S]-5-methyltetrahydrofolate or folic acid equally reduces serum homocysteine concentrations in older adults

Ewa Sicińska

International Journal of Food Sciences and Nutrition, 2017

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Plasma homocysteine, a risk factor for cardiovascular disease, is lowered by physiological doses of folic acid

Mary Ward

QJM, 1997

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Randomized Trial of Folic Acid Supplementation and Serum Homocysteine Levels

John Scott

Archives of Internal Medicine, 2001

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5,10-methylenetetrahydrofolate reductase common mutations, folate status and plasma homocysteine in healthy French adults of the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) cohort

Khalil Rabhi

British Journal of Nutrition, 2000

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The effect of folic acid supplementation on plasma homocysteine in an elderly population

Michael Golden

QJM, 2002

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Effects of Riboflavin and Folic Acid Supplementation on Plasma Homocysteine Levels in Healthy Subjects

Joseph Su

The American Journal of the Medical Sciences, 2006

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Long-term Effects of Folic Acid Fortification and B-vitamin Supplementation on Total Folate, Homocysteine, Methylmalonic Acid and Cobalamin in Older Adults

Angeles Colin Garcia

Canadian Journal of Public Health, 2008

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Effect of multivitamins on plasma homocysteine in patients with the 5,10 methylenetetrahydrofolate reductase C677T homozygous state

Elena Pacella

Molecular Medicine Reports, 2013

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The effect of folic acid fortification on plasma folate and total homocysteine concentrations

Andrew Bostom

1999

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Response of serum and red blood cell folate concentrations to folic acid supplementation depends on methylenetetrahydrofolate reductase C677T genotype: Results from a crossover trial

Shirley Beresford

Molecular Nutrition & Food Research, 2013

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Folate, Vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center

Erich de Paula, Luis Bittar

Nutrition Journal, 2015

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Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials

Geraldine Cuskelly

2005

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Plasma homocysteine concentrations in Greek children are influenced by an interaction between the methylenetetrahydrofolate reductase C677T genotype and folate status

Antonis Zampelas

The Journal of nutrition, 2005

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G1793A polymorphisms in the methyl- enetetrahydrofolate gene: Effect of folic acid on homocysteine levels

Sandra Melo

Molecular Nutrition & Food Research, 2006

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Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort

Paul Jacques

2003

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Choline Intake, Plasma Riboflavin, and the Phosphatidylethanolamine N-Methyltransferase G5465A Genotype Predict Plasma Homocysteine in Folate-Deplete Mexican-American Men with the Methylenetetrahydrofolate Reductase 677TT Genotype

Claudia Solis

Journal of Nutrition, 2009

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Total plasma homocysteine, folate, and vitamin b12 status in healthy Iranian adults: the Tehran homocysteine survey (2003–2004)/a cross–sectional population based study

Fatemeh Bandarian

2006

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