Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation (original) (raw)

Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation 1 1 Edited by J. Karn

Yossef Kliger

J Mol Biol, 2000

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Mode of Action of an Antiviral Peptide from HIV-1

Yossef Kliger

Journal of Biological Chemistry, 2001

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Mode of Action of an Antiviral Peptide from HIV-1. INHIBITION AT A POST-LIPID MIXING STAGE

Yossef Kliger

Journal of Biological Chemistry, 2001

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Conformational Changes in HIV-1 gp41 in the Course of HIV-1 Envelope Glycoprotein-Mediated Fusion and Inactivation †

G. Marius Clore FRS

Biochemistry, 2005

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Inhibiting HIV-1 Entry

Debra Eckert

Cell, 1999

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Membrane-Anchored Inhibitory Peptides Capture Human Immunodeficiency Virus Type 1 gp41 Conformations That Engage the Target Membrane prior to Fusion

dorothee von laer

Journal of Virology, 2006

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Propensity for a Leucine Zipper-Like Domain of Human Immunodeficiency Virus Type 1 gp41 to Form Oligomers Correlates with a Role in Virus-Induced Fusion Rather than Assembly of the Glycoprotein Complex

Terrence Hunter

Proceedings of The National Academy of Sciences, 1994

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Structural Investigation of the HIV-1 Envelope Glycoprotein gp160 Cleavage Site, 2: Relevance of an N-Terminal Helix

L. Falcigno, Gabriella D'Auria

ChemBioChem, 2003

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Biophysical Characterization of the Structure of the Amino-terminal Region of gp41 of HIV-1. IMPLICATIONS ON VIRAL FUSION MECHANISM

Ding-kwo Chang

Journal of Biological Chemistry, 1999

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Membrane interactions of the synthetic N-terminal peptide of HIV-1 gp41 and its structural analogs

Mark Sherman

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1999

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The LLSGIV stretch of the N-terminal region of HIV-1 gp41 is critical for binding to a model peptide, T20

Ding-kwo Chang

Protein …, 2003

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Fusion Peptides Derived from the HIV Type 1 Glycoprotein 41 Associate within Phospholipid Membranes and Inhibit Cell-Cell Fusion. STRUCTURE-FUNCTION STUDY

Yossef Kliger

Journal of Biological Chemistry, 1997

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HIV-1 Membrane Fusion Mechanism: Structural Studies of the Interactions between Biologically-Active Peptides from gp41

Kelly Guthrie

Biochemistry, 1996

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Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

Sonu Kumar

Nature Communications, 2019

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A Covalent Inhibitor Targeting an Intermediate Conformation of the Fusogenic Subunit of the HIV-1 Envelope Complex

Xicai Huang

Journal of Biological Chemistry, 2007

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Membrane-induced conformational change during the activation of HIV-1 gp41 1 1 Edited by A. R. Fersht

Yossef Kliger

J Mol Biol, 2000

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Biophysical evidence of two docking sites of the carboxyl heptad repeat region within the amino heptad repeat region of gp41 of human immunodeficiency virus type 1

Ding-kwo Chang

Antiviral Research, 2007

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Structural Analysis and Assembly of the HIV-1 Gp41 Amino-Terminal Fusion Peptide and the Pretransmembrane Amphipathic-At-Interface Sequence †

David Andreu

Biochemistry, 2006

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Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation

Gabriel Frank

PLoS Pathogens, 2012

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Membrane-induced conformational change during the activation of HIV-1 gp41

Yossef Kliger

Journal of Molecular Biology, 2000

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Conformational Stability and Membrane Interaction of the Full-Length Ectodomain of HIV-1 gp41: Implication for Mode of Action †

Richard Epand

Biochemistry, 2009

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HIV gp41 C-terminal Heptad Repeat Contains Multifunctional Domains: RELATION TO MECHANISMS OF ACTION OF ANTI-HIV PEPTIDES

Byron Cheung

Journal of Biological Chemistry, 2007

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Cooperative subunit interactions within the oligomeric envelope glycoprotein of HIV-1: Functional complementation of specific defects in gp120 and gp41

Edward Berger

Proceedings of the National Academy of Sciences, 2000

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Temperature-Dependent Intermediates in HIV-1 Envelope Glycoprotein-Mediated Fusion Revealed by Inhibitors that Target N- and C-Terminal Helical Regions of HIV-1 gp41

G. Marius Clore FRS

Biochemistry, 2004

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Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion

Stephen Harrison

Proceedings of the National Academy of Sciences, 2006

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Structural and Functional Roles of HIV-1 gp41 Pretransmembrane Sequence Segmentation

Ibon Iloro

Biophysical Journal, 2003

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The Conserved Residue Arg46 in the N-Terminal Heptad Repeat Domain of HIV-1 gp41 Is Critical for Viral Fusion and Entry

lu lu

PLoS ONE, 2012

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Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket

Steve Anderson

Bioorganic & Medicinal Chemistry Letters, 2010

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Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region

Debra Eckert

Proceedings of the National Academy of Sciences of the United States of America, 2001

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Prediction and validation of HIV-1 gp41 ecto-transmembrane domain post-fusion trimeric structure using molecular modeling

biswajit gorai

Journal of Biomolecular Structure and Dynamics, 2019

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Conformational Differences Between Functional Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Trimers and Stabilized Soluble Trimers

Hanh Nguyen

Journal of Virology, 2018

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Role for the Terminal Clasp of HIV-1 gp41 Glycoprotein in the Initiation of Membrane Fusion

David Stapleton

Journal of Biological Chemistry, 2011

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Identification of membrane-active regions of the HIV-1 envelope glycoprotein gp41 using a 15-mer gp41-peptide scan

Roberto Pascual

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2004

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A Peptide from the Heptad Repeat of Human Immunodeficiency Virus gp41 Shows both Membrane Binding and Coiled-Coil Formation

Mark Rabenstein

Biochemistry, 1995

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Computational study of bindings of HL9, a nonapeptide fragment of human lysozyme, to HIV1 fusion protein gp41

Dwi Angelina

Bioorganic & Medicinal Chemistry Letters, 2011

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