Prediction and validation of HIV-1 gp41 ecto-transmembrane domain post-fusion trimeric structure using molecular modeling (original) (raw)

Molecular dynamics studies of the transmembrane domain of gp41 from HIV-1

Donald Engelman

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009

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Structure Identification of Gp41 [HIV-1] Protein and Computational Analysis of its Binding Sites

VINOD RISHI

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Biophysical evidence of two docking sites of the carboxyl heptad repeat region within the amino heptad repeat region of gp41 of human immunodeficiency virus type 1

Ding-kwo Chang

Antiviral Research, 2007

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Membrane interactions of the synthetic N-terminal peptide of HIV-1 gp41 and its structural analogs

Mark Sherman

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1999

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Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion

Temple Burling

Journal of virology, 1999

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Identification of a Critical Motif for the Human Immunodeficiency Virus Type 1 (HIV-1) gp41 Core Structure: Implications for Designing Novel Anti-HIV Fusion Inhibitors

Qiuyun Dai

Journal of Virology, 2008

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The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region

Kouhei Tsumoto

Journal of Biological Chemistry, 2015

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Biophysical Characterization of the Structure of the Amino-terminal Region of gp41 of HIV-1. IMPLICATIONS ON VIRAL FUSION MECHANISM

Ding-kwo Chang

Journal of Biological Chemistry, 1999

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Membrane structure of the human immunodeficiency virus gp41 fusion peptide by molecular dynamics simulation

Tuck Wong

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003

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Atomic structure of a thermostable subdomain of HIV-1 gp41

Jia-huai Wang

Proceedings of the National Academy of Sciences, 1997

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Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions

Winfried Weissenhorn

PLoS Pathogens, 2010

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Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery

Jean Severin

Journal of Computer-Aided Molecular Design, 2007

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HIV gp41 C-terminal Heptad Repeat Contains Multifunctional Domains: RELATION TO MECHANISMS OF ACTION OF ANTI-HIV PEPTIDES

Byron Cheung

Journal of Biological Chemistry, 2007

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The LLSGIV stretch of the N-terminal region of HIV-1 gp41 is critical for binding to a model peptide, T20

Ding-kwo Chang

Protein …, 2003

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Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation

Yossef Kliger

Journal of Molecular Biology, 2000

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X-ray Crystallographic Study of an HIV-1 Fusion Inhibitor with the gp41 S138A Substitution

Hiroaki Ohno

Journal of Molecular Biology, 2009

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The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core

john skehel

Bioorganic & Medicinal Chemistry, 2000

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Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation 1 1 Edited by J. Karn

Yossef Kliger

J Mol Biol, 2000

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Conformational Stability and Membrane Interaction of the Full-Length Ectodomain of HIV-1 gp41: Implication for Mode of Action †

Richard Epand

Biochemistry, 2009

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Computational study of bindings of HL9, a nonapeptide fragment of human lysozyme, to HIV1 fusion protein gp41

Dwi Hartono

Bioorganic & Medicinal Chemistry Letters, 2011

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Proposed atomic structure of a truncated human immunodeficiency virus glycoprotein gp120 derived by molecular modeling: target CD4 recognition and docking mechanism

Jerome Gabriel

Proceedings of the National Academy of Sciences of the United States of America, 1993

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Molecular structure at sites of HIV-1 gp120-CD4 interaction

Daphne Moffett

1997

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Origins of Resistance to the HIVgp41 Viral Entry Inhibitor T20

Brian McGillick

Biochemistry, 2010

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HIV-1 Membrane Fusion Mechanism: Structural Studies of the Interactions between Biologically-Active Peptides from gp41

Kelly Guthrie

Biochemistry, 1996

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Structural Analysis and Assembly of the HIV-1 Gp41 Amino-Terminal Fusion Peptide and the Pretransmembrane Amphipathic-At-Interface Sequence †

David Andreu

Biochemistry, 2006

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Structural and Functional Roles of HIV-1 gp41 Pretransmembrane Sequence Segmentation

Ibon Iloro

Biophysical Journal, 2003

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Mode of Action of an Antiviral Peptide from HIV-1. INHIBITION AT A POST-LIPID MIXING STAGE

Yossef Kliger

Journal of Biological Chemistry, 2001

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Conserved Salt Bridge between the N- and C-Terminal Heptad Repeat Regions of the Human Immunodeficiency Virus Type 1 gp41 Core Structure Is Critical for Virus Entry and Inhibition

Asim Kumar Debnath

Journal of Virology, 2008

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Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion

Stephen Harrison

Proceedings of the National Academy of Sciences, 2006

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Interaction of the Major Epitope Region of HIV Protein gp41 with Membrane Model Systems. A Fluorescence Spectroscopy Study

Nuno Santos

Biochemistry, 1998

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Membrane-induced conformational change during the activation of HIV-1 gp41 1 1 Edited by A. R. Fersht

Yossef Kliger

J Mol Biol, 2000

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Conformational Partitioning of the Fusion Peptide of HIV-1 gp41 and Its Structural Analogs in Bilayer Membranes

Marjorie Longo

Biophysical Journal, 2002

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HIV gp41 C-terminal Heptad Repeat Contains Multifunctional Domains

Steven Jiang

Journal of Biological Chemistry, 2007

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The C4 region as a target for HIV entry inhibitors - NMR Mapping of the interacting segments of T20 and gp120

Fred Naider

The FEBS journal, 2015

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Mode of Action of an Antiviral Peptide from HIV-1

Yossef Kliger

Journal of Biological Chemistry, 2001

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