On the inhibition of 5-lipoxygenase product formation by tryptanthrin: mechanistic studies and efficacy in vivo (original) (raw)

On the inhibition of 5‐lipoxygenase product formation by tryptanthrin: mechanistic studies and efficiency in vivo

Matthias Hamburger

2011

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Inhibitory Activity of Tryptanthrin on Prostaglandin and Leukotriene Synthesis

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L-652,343, a novel dual cyclo/lipoxygenase inhibitor, inhibits LTB4-production by stimulated human polymorphonuclear cells but not by stimulated human whole blood

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(9-[4-acetyl-3-hydroxy-2-n-propylphenoxy) methyl]-3-(1H-tetrazol-5-yl)-4H-pyrido [1,2-a] pyrimidin-4-one), AS-35, inhibits leukotriene synthesis

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Anthony Kreft

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The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo

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