Riyadh Mother and Baby Multicenter Cohort Study: The Cohort Profile (original) (raw)
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Family medicine and primary care, 2021
Background: Pregnancy is a diabetogenic condition, with Gestational Diabetes Mellitus (GDM) developing in 3 to 25% of all pregnancies. GDM has unfavorable short-and long-term consequences for both mothers and their children. We conducted this study aiming to assess the prevalence of gestational diabetes and associated risk factors during pregnancy in Riyadh, Saudi Arabia. Methods: This was a retrospective cross-sectional survey study. GDM diagnosis was based on the universal two-hour 75 g OGTT. GDM cases were defined using the 75 g OGTT with at least one value of plasma glucose concentration equals to or exceeds the thresholds of 92 mg/dl, 180 mg/dl, and 153 mg/dl for fasting one-hour, and 2-hour post glucose, respectively. The data was collected by the study authors from patients' files using a data collection form that included the oral glucose tolerance test results in addition to the participants' socio-demographic data. Results: A total of 384 pregnant women were recruited, the highest percentage (29.7%) of them aged 26 to 30 years old, 35% were overweight and 24.5% were obese, and 72.4% were multi-parity. Based on the 2h OGTT, the prevalence of GDM was 32.6%. The univariate logistic regression analysis showed that old age, low educational level, higher BMI, family history of DM, higher rates of multi-parity, abortions, C-sections, and hypothyroidism were significant risk factors for GDM. On the other hand, there were no significant associations between occupational status, PCOS, preeclampsia, hypertension, asthma, and GDM. Conclusion: GDM diagnosed on basis of the OGTT criteria was very common among pregnant women in Saudi Arabia. Overweight and obesity as well as older age were associated with an increased risk of GDM. Also, low educational level, family history of DM, GDM history, history of abortion, and C-section were all significant risk factors of GDM.
BioMed Research International, 2017
The objectives of this study were to estimate the burden of diabetes and to explore the adverse pregnancy outcomes associated with pregestational diabetes mellitus (pre-GDM) and gestational diabetes mellitus (GDM) among the Saudi pregnant population. In this subcohort, we compared the maternal and the neonatal outcomes of diabetic women with pre-GDM and GDM to the outcomes of nondiabetic mothers who delivered during the same period. From the total cohort, 9723 women participated in this study. Of the participants, 24.2% had GDM, 4.3% had pre-GDM, and 6951 were nondiabetic. After adjustment for confounders, women with GDM had increased odds of delivering a macrosomic baby (OR: 1.6; 95% CI: 1.2–2.1). Women with pre-GDM were more likely to deliver by Cesarean section (OR: 1.65; CI: 1.32–2.07) and to have preterm delivery < 37 weeks (OR: 2.1; CI: 1.5–2.8). Neonates of mothers with pre-GDM were at increased risk of being stillbirth (OR: 3.66; CI: 1.98–6.72), at increased risk of admis...
International journal of clinical and experimental medicine, 2015
The presence of either diabetes mellitus type 2 (DMT2) or GDM constitute a high-risk pregnancy. Given the high rate of DMT2 and GDM in the kingdom of Saudi Arabia (KSA), no study has ever compared whether GDM outcomes are comparable to those with DMT2. The present study aims to compare for the first time, maternal and neonatal outcomes among Saudi patients with GDM, DMT2 and non-DM groups. This is a retrospective study covering data from 1718 pregnant patients admitted at King Fahad Medical City, Riyadh, KSA from April 2011 to March 2013. The prevalence of GDM was 13.8%, DMT2 was 0.9%. DMT2 group had the highest mean parity and shortest mean gestational age as compared to other groups. Half of all the subjects in the DMT2 group also experienced preterm labor, as opposed to only 10% in GDM and 14% in the non-DM group, respectively. Finally, neonates delivered by DMT2 mothers had the highest percentage of admissions to NICU (33%) as compared to 10% in the non-DM group and only 5% in t...
Obesity Among Pregnant Women in Saudi Arabia: A Retrospective Single-Center Medical Record Review
Cureus, 2021
Background Obesity in Saudi Arabia is on the rise, especially among females who are more likely to suffer from obesity in the reproductive age group than males in the adult age group. Biologically, pregnancy can increase women's weight and put them at greater risk for adverse obstetric outcomes. Objectives To find the prevalence of obesity among pregnant women and their obstetric outcomes. Methods This retrospective study was conducted on pregnant women who delivered between January 2013 and May 2018 at the obstetrics clinic of King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia. A datasheet was formed to collect data from the medical records of these pregnant women. The analysis was done using the Statistical Package for Social Sciences (SPSS), version 26 (IBM SPSS Statistics, Armonk, NY). A p-value of < 0.05 was used to calculate statistical significance. Results A total of 9,095 pregnant women delivered during that period. Of those women, a total of 2,235 were found to be obese, and 1,842 were included in the study. A total of 1,130 women were categorized under Class I obesity, 458 were categorized under Class II obesity, and 254 were categorized under Class III obesity. The majority of the sample were Saudis (72.3%) and young adults (90.8%) with 1,672 cases. The average age was 31.7 (standard deviation (SD): 5.9). Twenty percent of the sample had preterm newborns, while the majority (62.4%) ended up with cesarean delivery. Advanced age, multipara, and cesarean delivery were statistically significant with adverse pregnancy outcomes (p < 0.05). Conclusion As demonstrated in this study, obesity among females in Saudi Arabia has increased over the past decade. Hence, this puts them at higher risk of developing adverse pregnancy outcomes, as pregnancy physiologically results in additional weight gain. Proper antenatal counseling, health education, and a comprehensive plan prior to conception are highly recommended.
Pakistan Journal of Medical Sciences
Objectives: We aimed to find out the prevalence and associated risk factors of GDM among females who attended antenatal clinic at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia (SA). Methods: This retrospective study was carried out from 25th September 2016 till 20th December 2016, at the Endocrine Clinic, Faculty of Medicine, KAUH, Jeddah, SA. A total of 5000 women attended antenatal clinic and 637 women were referred to the endocrine clinic for GDM. The data of only 103 GDM was included in the study because only these patients’ complete data was available. The electronic record of 93 pregnant age and BMI matched females, not having GDM were selected as a control group. Results: The prevalence of GDM was 12.75% (637/5000). Parity was associated with GDM (X2=16.82, P=.001) and GDM was significantly higher in multigravida while no association of GDM was found with working status, place of living, hypertension, family history of DM and BMI. Logistic regression analysi...
Gestational diabetes among Saudi women: prevalence, risk factors and pregnancy outcomes
Annals of Saudi Medicine, 2015
G estational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with the onset or first recognition during pregnancy. 1,2 Previously, the prevalence of GDM was reported to range from 1 to 14%, depending on the population studied and the diagnostic tests employed. 3,4 However, the prevalence of GDM has increased since 2010 by 2to 3-fold, ranging from 8.9 to 53.4%. 5-15 This increment is mainly due to the adoption of the new criteria proposed by the International Association of Diabetes and
World Family Medicine Journal /Middle East Journal of Family Medicine
Background: Gestational Diabetes Mellitus (GDM) is recognized as one of the most common preventable diseases related to perinatal and maternal deaths. Despite the high prevalence of the condition worldwide, research cites limited knowledge about the affected population of pregnant women in Saudi Arabia. The main aim of this study was to assess pregnant women’s knowledge of GDM and its implications for the mother and fetus. Methods and Materials: The study utilized an interview-based questionnaire-based cross-sectional study design that targeted pregnant women coming for antenatal care visits in public health care centers in Riyadh city. Results: One hundred and forty-three pregnant women participated. 35.5% of the population had adequate knowledge of GDM and its implications, 34.7% did not have enough understanding of the condition, and a further 29.8% were not aware of the complication. Knowledge about GDM was found to be statistically significant only with the number of pregnancie...
2021
The rising prevalence of obesity has a significant impact on obstetrics practice regarding maternal and perinatal complications includes recurrent miscarriage, pregnancy-induced hypertension, preeclampsia, gestational diabetes, and prolonged labor. Objective: To assess the impact of obesity on pregnancy and neonatal outcomes among Saudi women. Methods: The study was conducted at King Abdul-Aziz Medical City, Jeddah. Design: A quantitative research, cross-sectional retrospective design. A total number of 186 participants were recruited from July to Dec.2018 according to eligibility criteria. The data were collected retrospectively by a review of the chart records of the labor and delivery department. Results: The mean (SD) age of participants was 31.94(5.67) years old; two-thirds were in obesity class1. There was a significant association between obesity and pre-existing thyroid disease and induced hypertension class3. However, Episiotomy showed that obesity class3 was significantly ...
Predictors of gestational diabetes mellitus in a highparity community in Saudi Arabia
Eastern Mediterranean Health Journal, 2010
A study in Riyadh, Saudi Arabia investigated the prevalence of gestational diabetes mellitus (GDM) and its predictors in a high-parity group of pregnant women (n = 633, 50.1% grand multiparas). The prevalence of GDM was 12.5% and 3.8% by World Health Organization and American Diabetes Association criteria respectively. Multiparous women were 8.29 times more likely to have GDM than nulliparous women. However, after adjustment for maternal age and history of abortion, nulliparous women were 2.95 times more likely to develop GDM than parous women. The probability of GDM for a parous woman increased from 2% to 21% when age increased from 20 to 40 years. The high rate of GDM among grand multiparas may be due to the confounding effect of maternal age.