Anti-Laminin Ig Transgenic for a Dual Specific B Cells Destined for Deletion in Mice {kappa} Editing Rescues Autoreactive (original) (raw)

Receptor editing: an approach by autoreactive B cells to escape tolerance

Denise Gay

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Antigen Receptor Editing in Anti-DNA Transitional B Cells Deficient for Surface IgM

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Alternative mechanisms of receptor editing in autoreactive B cells

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Receptor editing and genetic variability in human autoreactive B cells

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Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens

Raul Torres

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Autoimmune NZB/NZW F1 mice utilize B cell receptor editing for generating high-affinity anti-dsDNA autoantibodies from low-affinity precursors

Nurit Cohen

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Receptor Editing as a Mechanism of B Cell Tolerance

Mark Schlissel

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Understanding B-cell tolerance through the use of immunoglobulin transgenic models

chandra mohan

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Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes

Klaus Rajewsky

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Positive and negative selection of antigen-specific B cells in transgenic mice expressing variant forms of the VH1 (T15) heavy chain

Philip Tucker, D. Longo

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Receptor Editing in Sereactive Bone Marrow B Cells

David Russell

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Anti–DNA B Cells in MRL/lpr Mice Show Altered Differentiation and Editing Pattern

Dongyao Ni

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B lymphocytes may escape tolerance by revising their antigen receptors

Marko Radic

Journal of Experimental Medicine, 1993

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Rearrangement of Mouse Immunoglobulin Kappa Deleting Element Recombining Sequence Promotes Immune Tolerance and Lambda B Cell Production

Jose Vela

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Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo

Arnold VJ

International Immunology, 2005

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Phenotype on Transgenic B Cells Receptor Confers a Tolerance-Like Expression of a V Region-Less B Cell

Alf Grandien

2000

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B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen

Luc Teyton, Michael Jackson

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Editing and escape from editing in anti-DNA B cells

Salar Khan

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Regulation of the B Cell Receptor Repertoire

Takayuki Ota

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B cells are anergic in transgenic mice that express IgM anti-DNA antibodies

Hilde Cheroutre

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Molecular underpinning of B-cell anergy

Yuval Yarkoni

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Peripheral B Cell Tolerance and Function in Transgenic Mice Expressing an IgD Superantigen

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Split Tolerance in Peripheral B Cell Subsets in Mice Expressing a Low Level of Ig-Reactive Ligand1

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B Cell Tolerance Checkpoints That Restrict Pathways of Antigen-Driven Differentiation 1

Chad Euler

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B Cell Tolerance Checkpoints That Restrict Pathways of Antigen-Driven Differentiation

Chad Euler

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Deletion of IgG-Switched Autoreactive B Cells and Defects in Faslpr Lupus Mice

Amanda Gavin

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B cell tolerance: Putting the horse before the cart

Garnett Kelsoe

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Persistence of partially functional double-stranded (ds) DNA binding B cells in mice transgenic for the IgM heavy chain of an anti-dsDNA antibody

Linda Spatz

International …, 2002

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Expression of a V Region-Less B Cell Receptor Confers a Tolerance-Like Phenotype on Transgenic B Cells

aimé vazquez

The Journal of Immunology, 2001

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Maintenance and loss of self-tolerance in B cells

Antonio Iglesias

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The efficiency of B cell receptor (BCR) editing is dependent on BCR light chain rearrangement status

Yuval Yarkoni

European Journal of Immunology, 2002

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Peripheral B cell receptor editing may promote the production of high-affinity autoantibodies in CD22-deficient mice

Nurit Cohen

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Virus-Like Display of a Neo-Self Antigen Reverses B Cell Anergy in a B Cell Receptor Transgenic Mouse Model

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