The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety: The parkinsonian toxin MPTP (original) (raw)

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

Muhammad Akram Phd

Journal of Neurochemistry, 2001

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Continuous MPTP intoxication in the Göttingen minipig results in chronic parkinsonian deficits

Arne Møller

Acta neurobiologiae experimentalis, 2016

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Classic toxin-induced animal models of Parkinson’s disease: 6-OHDA and MPTP

sanjeevi suganthi krishnan

Cell and Tissue Research, 2004

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Biochemical Events in the Development of Parkinsonism Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine

Rona Ramsay

Journal of Neurochemistry, 1987

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Search for neurotoxins structurally related to 1-methyl-4-phenylpyridine (MPP+) in the pathogenesis of Parkinson's disease

Carol Markey

Brain Research, 1992

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MPTP-induced mouse model of Parkinson’s disease: A promising direction of therapeutic strategies

Che Norma Mat Taib

Bosnian Journal of Basic Medical Sciences, 2020

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Toxin-induced models of Parkinson’s disease

Celine Perier

NeuroRX, 2005

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MPTP-induced mouse model of Parkinson’s disease: A promising direction for therapeutic strategies

Che Norma Mat Taib

Bosn J Basic Med Sci, 2020

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The Parkinsonian Neurotoxin 1-Methyl-4-Phenylpyridinium (MPP + ) Mediates Release of l -3,4-Dihydroxyphenylalanine ( l -DOPA) and Inhibition of l -DOPA Decarboxylase in the Rat Striatum: A Microdialysis Study

Glenn Dryhurst

Chemical Research in Toxicology, 2003

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Neurotoxin models and treatments of Parkinson’s disease

Sanjar Alam

International journal of health sciences

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The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease

Jorge Florio

Experimental Neurology, 2006

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Toxin-Induced Parkinson’s Disease Models

gokul krishna

Neuro – Open Journal, 2017

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Stable parkinsonian syndrome and uneven loss of striatal dopamine fibres following chronic MPTP administration in baboons

Philippe Hantraye

Neuroscience, 1993

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Mechanism of the neurotoxicity of MPTP: An update

Rona Ramsay

Febs Letters, 1990

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Mechanism of the neurotoxicity of MPTP

Rona Ramsay

FEBS Letters, 1990

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Synthetic and Natural Environmental Compounds as Potential Facilitators of Mptp-Induced Parkinsonism

Celia Dodd

2009

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Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Annick Prigent, Claude Sebban, Jean Mariani

Journal of Neurochemistry, 2012

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Spinal cord degeneration in C57BL/6N mice following induction of experimental parkinsonism with MPTP

Supriti Samantaray

Journal of Neurochemistry, 2008

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The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity

Julie Lotharius

The Journal of biological chemistry, 2000

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Potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium: Selective toxicity of 1-methyl-4-(4′-acetamidophenyl)-pyridinium and 1-methyl-4-cyclohexylpyridinium for dopaminergic neurons in culture

Simon Efange

Experimental Neurology, 1990

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Experimental Animal Models of Parkinson’s Disease: A Neurotoxin Overview

Dr. Rahul Deshmukh, Ashwani Kumar

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MPTP-induced Parkinsonism in minipigs: A behavioral, biochemical, and histological study

Arne Møller

Neurotoxicology and Teratology

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Neurotoxin-based models of Parkinson's disease

Celine Perier

Neuroscience, 2012

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Behavioral changes are not directly related to striatal monoamine levels, number of nigral neurons, or dose of parkinsonian toxin MPTP in mice

Charles Cohen-Salmon

Neurobiology of Disease, 2003

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Behavioral Tests in Neurotoxin-Induced Animal Models of Parkinson's Disease

Dr. E. Maruthi Prasad

Antioxidants, 2020

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IV. Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects

Sanford Markey

Life Sciences, 1985

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Neurotoxic_in_vivo_models_of_Parkinson_s_disease-_recent_advances

Franklyn Rocha Cabrero

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Influence of intranasal exposure of MPTP in multiple doses on liver functions and transition from non-motor to motor symptoms in a rat PD model

Dr. Kavina Ganapathy

Naunyn-Schmiedeberg's Archives of Pharmacology, 2019

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