First AID (Activation-induced Cytidine Deaminase) Is Needed to Produce High Affinity Isotype-switched Antibodies
Phuong Pham
Journal of Biological Chemistry, 2006
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The Common Key to Class-Switch Recombination and Somatic Hypermutation: Discovery of AID and Its Role in Antibody Gene Diversification
Junghyun Lim
The Journal of Immunology
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Faculty of 1000 evaluation for Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation
Janet Stavnezer
F1000 - Post-publication peer review of the biomedical literature, 2006
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AID mutant analyses indicate requirement for class-switch-specific cofactors
Nadia Catalan
Nature Immunology, 2003
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Replacement of I 3 germ-line promoter by I 1 inhibits class-switch recombination to IgG3
Ahmed Khamlichi
Proceedings of the National Academy of Sciences, 2007
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AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination
Joseph Pucella
Frontiers in immunology, 2014
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Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
Abhishek datta
Advances in Immunology, 2007
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Somatic hypermutation targeting is influenced by location within the immunoglobulin V region
Yoram Louzoun
Molecular immunology, 2011
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Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination
A. Sebrell
Proceedings of the National Academy of Sciences, 2013
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The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88
Capucine Picard
Nature Immunology, 2010
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Antibody class switching: uncoupling S region accessibility from transcription
Janet Stavnezer
Trends in Genetics, 2004
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Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions
Ahmed Khamlichi
Proceedings of the National Academy of Sciences, 2010
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Sense transcription through the S region is essential for immunoglobulin class switch recombination
Ahmed Khamlichi
The EMBO Journal, 2011
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Sγ3 switch sequences function in place of endogenous Sγ1 to mediate antibody class switching
Peter Goff
The Journal of experimental …, 2008
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Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes
Reiko Shinkura
International Immunology, 2009
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Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data
gur yaari
Frontiers in Immunology, 2013
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Immunoglobulin Somatic Hypermutation
Grace Teng
Annual Review of Genetics, 2007
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A class switch control region at the 3′ end of the immunoglobulin heavy chain locus
Michel Cogné
Cell, 1994
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Faculty of 1000 evaluation for Activation-induced cytidine deaminase mediates central tolerance in B cells
Michael Lieber
F1000 - Post-publication peer review of the biomedical literature, 2011
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Characterization of a new V gene replacement in the absence of activation-induced cytidine deaminase and its contribution to human B-cell receptor diversity.
Hussein Ghamlouch
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Targeting of AID-mediated sequence diversification to immunoglobulin genes
David Schatz
Current Opinion in Immunology, 2011
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The Block in Immunoglobulin Class Switch Recombination Caused by Activation-Induced Cytidine Deaminase Deficiency Occurs Prior to the Generation of DNA Double Strand Breaks in Switch Region1
Nadia Catalan
2000
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Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity
thinh tran
International Immunology, 2010
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The immunoglobulin heavy-chain locus hs3b and hs4 3′ enhancers are dispensable for VDJ assembly and somatic hypermutation
Michel Cogné
Blood, 2003
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The Block in Immunoglobulin Class Switch Recombination Caused by Activation-Induced Cytidine Deaminase Deficiency Occurs Prior to the Generation of DNA Double Strand Breaks in Switch μ Region
Nadia Catalan
Journal of Immunology, 2003
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Violation of an Evolutionarily Conserved Immunoglobulin Diversity Gene Sequence Preference Promotes Production of dsDNA-Specific IgG Antibodies
Mohamed Khass, André Vale
PloS one, 2015
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Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells
Michel Cogné
The Journal of Immunology, 2005
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Biochemical Analysis of Hypermutational Targeting by Wild Type and Mutant Activation-induced Cytidine Deaminase
Phuong Pham
Journal of Biological Chemistry, 2004
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Enhanced Evolvability in Immunoglobulin V Genes Under Somatic Hypermutation
Lindsay Cowell
Journal of Molecular Evolution, 1999
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Homologous Elements hs3a and hs3b in the 3′ Regulatory Region of the Murine Immunoglobulin Heavy Chain (Igh) Locus Are Both Dispensable for Class-switch Recombination
Fatmata binta Bah
Journal of Biological Chemistry, 2011
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Contribution of Receptor Editing to the Antibody Repertoire
Rafael Casellas
Science, 2001
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Increased Targeting of Donor Switch Region and IgE in S 1-Deficient B Cells
S. Misaghi
The Journal of Immunology, 2010
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