Expression, purification and cell cytotoxicity of actin-modifying binary toxin from Clostridium difficile (original) (raw)

The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile

Raquel Godoy-Ruiz

International Journal of Molecular Sciences

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Biochemical studies on the effect of Clostridium difficile toxin B on actin in vivo and in vitro

Barbara Laughon

Infection and immunity, 1987

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Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin

Roland Benz

Toxins, 2021

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Clostridium difficile Toxins: Mechanism of Action and Role in Disease

Charles Darkoh

Clinical Microbiology Reviews, 2005

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Difference in F-actin depolymerization induced by toxin B from the Clostridium difficile strain VPI 10463 and toxin B from the variant Clostridium difficile serotype F strain 1470

Harald Genth

2013

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Production of a complete binary toxin (actin-ADP-ribosylating toxin) by Clostridium difficile CD196

Pierre Bourlioux

Infection and Immunity

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Membrane Translocation of Binary Actin-ADP-Ribosylating Toxins from Clostridium difficile and Clostridium perfringens Is Facilitated by Cyclophilin A and Hsp90

Gunter Fischer

Infection and Immunity, 2011

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Production of a Complete Binary Toxin (Actin-Specific ADP Ribosyltransferase) byClostridium difficileCD196

Pierre Bourlioux

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The role of toxin A and toxin B in Clostridium difficile infection

Sarah Kuehne

Nature, 2010

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Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal Effects

Stefano Di Bella

Toxins, 2016

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Regulation of Toxin Synthesis by Clostridium Difficile

Charles Darkoh

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Both, toxin A and toxin B, are important in Clostridium difficile infection

Sarah Kuehne

Gut Microbes, 2011

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Overlapping Roles for Toxins in Clostridium difficile Infection

Philip Hanna

Journal of Infectious Diseases, 2014

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Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain

Sarah Kuehne

Journal of Infectious Diseases, 2014

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Toxins A and B of Clostridium difficile

Maurice J.h.m. Wolfhagen

FEMS Microbiology Reviews, 1994

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Tailored Cyclodextrin Pore Blocker Protects Mammalian Cells from Clostridium difficile Binary Toxin CDT

Vladimir Karginov

Toxins, 2014

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Toxin B is essential for virulence of Clostridium difficile

Dale Gerding

Nature, 2009

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Clinical features of Clostridium difficile-associated diarrhoea due to binary toxin (actin-specific ADP-ribosyltransferase)-producing strains

Dominique Decré

Journal of Medical Microbiology, 2005

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Proteomic Analysis and Label-Free Quantification of the Large Clostridium difficile Toxins

Adrian Woolfitt

International Journal of Proteomics, 2013

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Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine

Pauline M Anton

Gastroenterology, 2003

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The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia

Madeline Wilson

Nature Microbiology, 2016

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Difference in the Cytotoxic Effects of Toxin B from Clostridium difficile Strain VPI 10463 and Toxin B from Variant Clostridium difficile Strain 1470

Harald Genth

Infection and Immunity, 2007

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Neutralization ofClostridium difficiletoxin A using antibody combinations

Jay M Short

mAbs, 2010

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Cellular Uptake of Clostridium difficile Toxin B

Christian Busch

Journal of Biological Chemistry, 2003

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Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine* 1

Pauline Anton

Gastroenterology, 2003

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Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab

Pulkit Gupta

Journal of molecular biology, 2017

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The Relative Role of Toxins A and B in the Virulence of Clotridioides difficile

Dale Gerding

2020

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Frequency of Binary Toxin Genes among Clostridium difficile Strains That Do Not Produce Large Clostridial Toxins

Dale Gerding

Journal of Clinical Microbiology, 2003

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Clostridium difficile toxin B induces reorganization of actin, vinculin, and talin in cultured cells

Michael Ottlinger

Experimental Cell Research, 1988

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Revised nomenclature of Clostridium difficile toxins and associated genes

Dale Gerding

Journal of Medical Microbiology, 2005

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Toxin Gene Analysis of a Variant Strain of Clostridium difficile That Causes Human Clinical Disease

Michelle Merrigan

Infection and Immunity, 2000

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