Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors (original) (raw)
Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen
Valentina Onnis
Journal of Enzyme Inhibition and Medicinal Chemistry
View PDFchevron_right
Chemistry around imidazopyrazine and ibuprofen: Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors
Jean-françois Rees
European Journal of Medicinal Chemistry, 2010
View PDFchevron_right
A Binding Site for Nonsteroidal Anti-inflammatory Drugs in Fatty Acid Amide Hydrolase
Elisa Romeo
Journal of the American Chemical Society, 2013
View PDFchevron_right
Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin
Valentina Onnis
European journal of pharmacology, 2007
View PDFchevron_right
Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode
Bruno Catalanotti
PloS one, 2015
View PDFchevron_right
Structural Modification of Ibuprofen as new NSAIDs via DFT, Molecular Docking and Pharmacokinetics Studies
Nathanael D Ojo
International Journal of Advances in Engineering and Pure Sciences, 2021
View PDFchevron_right
A Novel Ibuprofen Derivative and Its Complexes: Physicochemical Characterization, DFT Modeling, Docking, In Vitro Anti-Inflammatory Studies, and DNA Interaction
Adel Orabi
Molecules
View PDFchevron_right
Synthesis and Quantitative Structure−Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl3-yl Alkylcarbamates
Giovanni Piersanti
Journal of Medicinal Chemistry, 2008
View PDFchevron_right
Molecular modifications of ibuprofen using Insilico modeling system
mullaicharam bhupathyraaj
International journal of Nutrition, Pharmacology, Neurological Diseases, 2012
View PDFchevron_right
Cyclohexylcarbamic Acid 3‘- or 4‘-Substituted Biphenyl3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling Studies
Giovanni Piersanti
Journal of Medicinal Chemistry, 2004
View PDFchevron_right
Functionalization of Ibuprofen Core Structure Compound:Synthesis of New Potential Chemotherapeutic Agents Incorporating Ibuprofen Substructure
Shaaban Mohamed
View PDFchevron_right
Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling
Giorgio Tarzia
Chemical Communications, 2008
View PDFchevron_right
In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity
Rosivaldo Borges
Molecules
View PDFchevron_right
Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors
Giorgio Tarzia
Journal of medicinal chemistry, 2003
View PDFchevron_right
Structure−Activity Relationships of α-Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase
anthony romero
Journal of Medicinal Chemistry, 2007
View PDFchevron_right
The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen
Valentina Onnis
Bioorganic Chemistry
View PDFchevron_right
Assessment of NSAIDS as Potential Inhibitors of the Fatty Acid Amide Hydrolase I (FAAH-1) using Three Different Primary Fatty Acid Amide Substrates In Vitro
Gideon Helegbe
2021
View PDFchevron_right
X-ray Crystallographic Analysis of α-Ketoheterocycle Inhibitors Bound to a Humanized Variant of Fatty Acid Amide Hydrolase
Mauro Mileni
Journal of Medicinal Chemistry, 2010
View PDFchevron_right
Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): Molecular docking and 3D-QSAR analyses on DHDMBF analogues
Mingyue Zheng
Bioorganic & Medicinal Chemistry, 2006
View PDFchevron_right
Theoretical Study of Isoindolines to Identify them as Cyclooxygenase-1 and -2 Inhibitors by Docking Simulations
Teresa Percino
Journal of the Mexican Chemical Society
View PDFchevron_right
Scaffold hopping-guided design of some isatin based rigid analogs as fatty acid amide hydrolase inhibitors: Synthesis and evaluation
SHIVANI JAISWAL
Biomedicine & Pharmacotherapy, 2018
View PDFchevron_right
Binding and Inactivation Mechanism of a Humanized Fatty Acid Amide Hydrolase by α-Ketoheterocycle Inhibitors Revealed from Cocrystal Structures
Mauro Mileni
Journal of the American Chemical Society, 2009
View PDFchevron_right
Molecular Modeling Study of 2-Substituted Isoindoline Derivatives of a-Amino Acids as Inhibitors of Lipoxygenase by Docking Simulations
Jose Daniel Pluas Basurto
Journal of the Mexican Chemical Society, 2019
View PDFchevron_right
Biological Evaluation and Molecular Docking Studies of Benzalkonium Ibuprofenate
Shameera Ahamed
Computational Biology and Chemistry [Working Title]
View PDFchevron_right
Design, synthesis, and structure–activity-relationship of phenyl imidazoles as potent Smoothened antagonists
Tove Tuntland
View PDFchevron_right
Crystal and enzyme environmental effects on ibuprofen and sila-ibuprofen
Florian Kleemiss
Acta Crystallographica, 2017
View PDFchevron_right
Ibuprofen and sila-ibuprofen: polarization effects in the crystal and enzyme environments
Florian Kleemiss
Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 2021
View PDFchevron_right