Tyrosine 785 is a major determinant of Trk--substrate interaction (original) (raw)
Direct interaction of nerve growth factor receptor, TrkA, with non‐receptor tyrosine kinase, c‐Abl, through the activation loop
Monica Ștefan
FEBS Letters, 2000
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The Cytoplasmic and Transmembrane Domains of the p75 and Trk A Receptors Regulate High Affinity Binding to Nerve Growth Factor
Diego Esposito
Journal of Biological Chemistry, 2001
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Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase.
David Loeb
Oncogene, 1998
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Nerve growth factor induces protein-tyrosine phosphorylation
Pamela Maher
Proceedings of the National Academy of Sciences, 1988
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The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3
Shuqian Jing
Cell, 1991
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NGF stimulation of erk phosphorylation is impaired by a point mutation in the transmembrane domain of trkA receptor
Philip Lazarovici
Journal of Molecular Neuroscience - J MOL NEUROSCI, 2000
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Nerve Growth Factor Stimulates Multisite Tyrosine Phosphorylation and Activation of the Atypical Protein Kinase C's via a src Kinase Pathway
Thangiah Geetha
Molecular and Cellular Biology, 2001
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Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells
Keren Ettinger, Gadi Cohen, Philip Lazarovici
Journal of molecular neuroscience : MN, 2014
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Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3
Susan Meakin
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006
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Cross talk among tyrosine kinase receptors in PC12 cells: desensitization of mitogenic epidermal growth factor receptors by the neurotrophic factors, nerve growth factor and basic fibroblast growth factor
Robert Ballotti
Molecular Biology of the Cell, 1993
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Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases
Michael Demarco
Cell, 1992
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Two Restricted Sites on the Surface of the Nerve Growth Factor Molecule Independently Determine Specific TrkA Receptor Binding and Activation
Ted Ebendal
Journal of Biological Chemistry, 1997
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Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors
Cinzia Volonté
The Journal of biological chemistry, 1993
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Autocrine regulation of nerve growth factor expression by Trk receptors
Alessandra Mallei
Journal of Neurochemistry, 2004
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A Purine Analog‐Sensitive Protein Kinase Activity Associates with Trk Nerve Growth Factor Receptors
David Loeb
Journal of neurochemistry, 1993
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TrkA Tyrosine Residues Involved in NGF-induced Neurite Outgrowth of PC12 Cells
Dan Lindholm
European Journal of Neuroscience, 1995
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Direct Binding of the Signaling Adapter Protein Grb2 to the Activation Loop Tyrosines on the Nerve Growth Factor Receptor Tyrosine Kinase, TrkA
Susan Meakin, Ela Gryz
Journal of Biological Chemistry, 2000
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The Signaling Adapter FRS-2 Competes with Shc for Binding to the Nerve Growth Factor Receptor, TrkA
Susan Meakin
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Long-term, heterologous down-regulation of the epidermal growth factor receptor in PC12 cells by nerve growth factor
Philip Lazarovici
The Journal of cell biology, 1987
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The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor
C. Drinkwater, Susan Meakin
Proceedings of the National Academy of Sciences, 1992
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TrkA NGF receptor plays a role in the modulation of p75NTR expression
Karen Mearow
Neuroscience Letters, 2005
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Lysine 63 Polyubiquitination of the Nerve Growth Factor Receptor TrkA Directs Internalization and Signaling
Thangiah Geetha
Molecular Cell, 2005
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Differential Activity of the Nerve Growth Factor (NGF) Antagonist PD90780 [7-(Benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic Acid] Suggests Altered NGF-p75NTR Interactions in the Presence of TrkA
Igor Shamovsky
Journal of Pharmacology and Experimental Therapeutics, 2004
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Cell cycle phase-specific surface expression of nerve growth factor receptors TrkA and p75(NTR)
D. Martín-zanca, Muriel Andrieu
The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998
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A Novel p75 Neurotrophin Receptor-Related Protein, NRH2, Regulates Nerve Growth Factor Binding to the TrkA Receptor
Pilar Perez
Journal of Neuroscience, 2004
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High Resolution Mapping of the Binding Site of TrkA for Nerve Growth Factor and TrkC for Neurotrophin-3 on the Second Immunoglobulin-like Domain of the Trk Receptors
Pantelis Tsoulfas
Journal of Biological Chemistry, 1998
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Expression of nerve growth factor and its high-affinity receptor, tyrosine kinase A proteins, in the human scalp skin
Mohamed Adly
Journal of Cutaneous Pathology, 2006
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Characterization and growth-dependent regulation of the nerve growth factor receptor gp140trk in rat C6 glioma cells
Lucia Petrelli
Molecular Brain Research, 1994
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