Author response: Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts (original) (raw)

Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts

Jasbir Dalal

2021

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Fragile X mental retardation protein regulates translation by binding directly to the ribosome

Manjuli Sharma

Molecular cell, 2014

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Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles

Marc-etienne Huot, E. Khandjian

Proceedings of the National Academy of Sciences, 2004

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Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis

Dilja Krueger

Molecular Autism, 2014

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The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif

Hervé Moine

The EMBO Journal, 2001

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Biology of the fragile X mental retardation protein, an RNA-binding protein

E. Khandjian

Biochemistry and Cell Biology, 1999

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A Novel Function for Fragile X Mental Retardation Protein in Translational Activation

Hervé Moine

PLoS Biology, 2009

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The FMRP/ GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum

Maria Catania

Nucleic Acids Research, 2015

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Fragile X Mental Retardation Protein: Nucleocytoplasmic Shuttling and Association with Somatodendritic Ribosomes

Yue Feng

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Excess ribosomal protein production unbalances translation in Fragile X Syndrome

Susana Louros

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Cell Type-Specific mRNA Dysregulation in Hippocampal CA1 Pyramidal Neurons of the Fragile X Syndrome Mouse Model

Jihane Vitre

Frontiers in Molecular Neuroscience, 2017

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Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function

Kirk B Jensen

Cell, 2001

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FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Robert Darnell

Cell, 2011

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RNA-Binding Specificity of the Human Fragile X Mental Retardation Protein

Youssi Athar

Journal of Molecular Biology, 2020

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HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein

Florence Rage

Nucleic acids research, 2018

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Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression

Marc-etienne Huot

Human Molecular Genetics, 2002

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Lost Once, the Fragile X Mental Retardation Protein is Now Back onto Brain Polyribosomes

Marc-etienne Huot

RNA Biology, 2005

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The Human Fragile X Mental Retardation Protein Inhibits the Elongation Step of Translation through its RGG and C-terminal domains

Youssi Athar

2020

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Fragile X Mental Retardation Protein: Many Partners and Multiple Targets for a Promiscuous Function

E. Khandjian

Current Genomics, 2005

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Cells Lacking the Fragile X Mental Retardation Protein (FMRP) have Normal RISC Activity but Exhibit Altered Stress Granule Assembly

Hervé Moine

Molecular Biology of the Cell, 2008

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The Fragile X Mental Retardation Protein FMRP Binds Elongation Factor 1A mRNA and Negatively Regulates Its Translation in Vivo

Sarah Nolin

Journal of Biological Chemistry, 2003

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A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

Pietro Chiurazzi

Nature Neuroscience, 2007

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A 3' untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR

Ravi Muddashetty

Proceedings of the National Academy of Sciences of the United States of America, 2015

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Regulatory BC1 RNA and the Fragile X Mental Retardation Protein: Convergent Functionality in Brain

Robert Wong

2010

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Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure

E. Khandjian

Nucleic Acids Research, 2006

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Bioinformatic Prediction of mRNA Targets of the Fragile X Mental Retardation Protein

Lyle Ungar

2005

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On BC1 RNA and the fragile X mental retardation protein

E. Khandjian

Proceedings of the National Academy of Sciences, 2008

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The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

E. Khandjian

Human Molecular Genetics, 1997

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Global ribosome profiling reveals that mutant huntingtin stalls ribosomes and represses protein synthesis independent of fragile X mental retardation protein

Nicole Galli

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The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development

Yue Feng

Proceedings of The National Academy of Sciences, 2004

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Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome

Yue Feng

Cell, 2001

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