Hydroxylated metabolites of the antimalarial drug primaquine (original) (raw)

Hydroxylated metabolites of the antimalarial drug primaquine. Oxidation and redox cycling.

Ohara Augusto

1992

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Enantioselective Pharmacokinetics of Primaquine in Healthy Human Volunteers

J. McChesney

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A new generation of 7-Chloro-4-Aminoquinoline antimalarials

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Systematic Reviews in Pharmacy, 2010

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Role of plant secondary metabolites as potential antimalarial drugs

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Bioequivalence of a new coated 15 mg primaquine formulation for malaria elimination

Bilal Ahmad Rahimi

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Antimalarial activity and pharmacokinetic properties of new chemical entities

Ntokozo Shirley Dambuza

2013

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Electron-capture gas chromatographic assay for primaquine in blood

Tuticorin G Rajagopalan

Journal of Chromatography B: Biomedical Sciences and Applications, 1981

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Studies on quinones. Part 35: Access to antiprotozoal active euryfurylquinones and hydroquinones

Hilda Leiva

Tetrahedron, 2002

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Repurposing Antimalarial Drug Mefloquine for Cancer Treatment

Conor Ronayne

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Primaquine revisited six decades after its discovery

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o -Benzoquinone dioxime

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Crystallography and Biopharmaceutics of Some Antimalarials

Augustine Okhamafe

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Second Generation Tetrahydroquinoline-Based Protein Farnesyltransferase Inhibitors as Antimalarials

Prakash Pendyala

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Antimalarial Benzoquinones from an Endophytic Fungus, Xylaria sp

Srinuan Tansuwan

Journal of Natural Products, 2007

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Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs

fatima nogueira

European Journal of Medicinal Chemistry, 2009

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Brian Grimberg

Pharmaceuticals, 2011

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Macromolecular prodrugs. XII. Primaquine conjugates: Synthesis and preliminary antimalarial evaluation

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Insights and Current Perspectives on Pharmacogenomics of Antimalarial Drugs

Julius O Soyinka

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Evaluation of Antimalarial Activity and Toxicity of a New Primaquine Prodrug

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Interactions among primaquine, malaria infection and other antimalarials in Thai subjects

Sasithon Pukrittayakamee

British Journal of Clinical Pharmacology, 1993

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Common Anti-Malarial Drug Prescriptionand Patient

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Neutral Heroin Impurities from Tetrahydrobenzylisoquinoline Alkaloids

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Quinine bis-conjugates with quinolone antibiotics and peptides: synthesis and antimalarial bioassay

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Toxicological Review of Herbal Medicinal Products on the Ugandan Market

Liberty Kwiringira, Joseph Iberet

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Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry

Larry Walker

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Cycloabiesesquine A, a unique sesquiterpenoid from Abies delavayi

Daneel Ferreira

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Isolation and antimalarial activity of peroxydisulfate oxidation products of primaquine

Virendra Dua

Bioorganic & Medicinal Chemistry Letters, 2002

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Direct ESR detection of a free radical intermediate during the peroxidase-catalyzed oxidation of the antimalarial drug primaquine

Ohara Augusto

Biochemical Pharmacology, 1988

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CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

Rebecca Barnhart, Michael Kozar

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Characterization of Plasmodium falciparum serine hydroxymethyltransferase—A potential antimalarial target

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Molecular and Biochemical Parasitology, 2009

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Case Report: A Case of Primaquine-Induced Hemoglobinuria in Glucose-6-Phosphate Dehydrogenase–Deficient Malaria Patient in Southeastern Bangladesh

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2-Chloro-3-hydroxymethyl-7,8-dimethylquinoline

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