Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1)
Suresh Ambudkar
PLOS ONE
View PDFchevron_right
Molecular analysis of the multidrug transporter, P-glycoprotein
Ursula Germann
Cytotechnology, 1998
View PDFchevron_right
Multiple Transport-Active Binding Sites Are Available for a Single Substrate on Human P-Glycoprotein (ABCB1)
Eduardo Chufan, Satyakam Singh, Suresh Ambudkar
PLoS ONE, 2013
View PDFchevron_right
Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity
Joseph Shiloach
Journal of Biological Chemistry, 2016
View PDFchevron_right
Role of membrane-embedded drug efflux ABC transporters in the cancer chemotherapy
sonu kumar gupta ME 42
Oncology Reviews, 2020
View PDFchevron_right
Contribution to Substrate Specificity and Transport of Nonconserved Residues in Transmembrane Domain 12 of Human P-Glycoprotein †
Suresh Ambudkar
Biochemistry, 1998
View PDFchevron_right
New light on multidrug binding by an ATP-binding-cassette transporter
Akanksha Bapna
Trends in Pharmacological Sciences, 2006
View PDFchevron_right
Transmembrane Inhibitors of P-Glycoprotein, an ABC Transporter
Nadya Tarasova
Journal of Medicinal Chemistry, 2005
View PDFchevron_right
STRUCTURE AND FUNCTION OF MULTIDRUG TRANSPORTER PROTEINS AND MECHANISM OF RESISTANCE TO AVAILABLE CHEMOTHERAPY
IJAR Indexing
View PDFchevron_right
Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets
Ian Kerr
The Biochemical journal, 2018
View PDFchevron_right
Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1
Hendrik W . van Veen
Trends in Biochemical Sciences, 2010
View PDFchevron_right
The P-glycoprotein multidrug transporter
André Guillouzo, V. Lecureur
General Pharmacology: The Vascular System, 1996
View PDFchevron_right
Positively Cooperative Sites for Drug Transport by P-Glycoprotein with Distinct Drug Specificities
Adam Shapiro
European Journal of Biochemistry, 1997
View PDFchevron_right
Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies
F. Sharom
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1999
View PDFchevron_right
The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion
Narakorn Khunweeraphong
Scientific Reports, 2017
View PDFchevron_right
Evidence for Modulatory Sites at the Lipid−Protein Interface of the Human Multidrug Transporter P-Glycoprotein
karobi moitra
View PDFchevron_right
A single active catalytic site is sufficient to promote transport in P-glycoprotein
Gábor Szalóki
Scientific reports, 2016
View PDFchevron_right
The role of multidrug transporters in drug availability, metabolism and toxicity
Flóra Szeri
Toxicology letters, 2003
View PDFchevron_right
Structure of a human multidrug transporter in an inward-facing conformation
Roger Deeley
Journal of Structural Biology, 2010
View PDFchevron_right
A multidrug ABC transporter with a taste for GTP
claire durmort
Scientific Reports, 2018
View PDFchevron_right
Human ABC transporter ABCG2 in cancer chemotherapy: drug molecular design to circumvent multidrug resistance
Hiroyuki Hirano
Methods in molecular biology (Clifton, N.J.), 2012
View PDFchevron_right
A critical role of a carboxylate in proton conduction by the ATP-binding cassette multidrug transporter LmrA
Hendrik W . van Veen
The FASEB Journal, 2005
View PDFchevron_right
Functional Role of Transmembrane Helix 6 in Drug Binding and Transport by the ABC Transporter MsbA †
Hendrik W . van Veen
Biochemistry, 2008
View PDFchevron_right
Development of inhibitors of ATP-binding cassette drug transporters – present status and challenges
Suresh Ambudkar
Expert Opinion on Drug Metabolism & Toxicology, 2008
View PDFchevron_right
Role of the MRP1/ABCC1 Multidrug Transporter Protein in Cancer
Murray Norris
IUBMB Life, 2007
View PDFchevron_right
Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter
Ian Kerr
British Journal of Pharmacology, 2006
View PDFchevron_right
P-Glycoprotein: A Critical Comparison of Models Depicting Mechanism of Drug Efflux and Role of Modulators
Dr. Rajesh Kumar Kesharwani
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 2014
View PDFchevron_right
Molecular Basis of Multidrug Transport by ATP-Binding Cassette Transporters: A Proposed Two-Cylinder Engine Model
bibi loe
2001
View PDFchevron_right
The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade
Charles Ashby
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2014
View PDFchevron_right
Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2
William Figg
Pharmacogenomics, 2005
View PDFchevron_right
Characterization of Drug Transport, ATP Hydrolysis, and Nucleotide Trapping by the Human ABCG2 Multidrug Transporter. MODULATION OF SUBSTRATE SPECIFICITY BY A POINT MUTATION
Balazs Sarkadi
Journal of Biological Chemistry, 2002
View PDFchevron_right
Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance
Yongcheng Zheng
Frontiers in Pharmacology, 2021
View PDFchevron_right
The Q loops of the human multidrug resistance transporter ABCB1 are necessary to couple drug binding to the ATP catalytic cycle
Anna Seelig
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014
View PDFchevron_right
Pharmacogenomics of ABC transporters and its role in cancer chemotherapy
Romano Danesi
Drug Resistance Updates, 2003
View PDFchevron_right