Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia (original) (raw)

Genomic Instability in Mice Is Greater in Fanconi Anemia Caused by Deficiency of Fancd2 than Fancg

Ramune Reliene

Cancer Research, 2010

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The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

F. Kruyt

Human molecular …, 2000

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Evidence for subcomplexes in the Fanconi anemia pathway

Miriam Ferrer

Blood, 2006

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On the role of FAN1 in Fanconi anemia

Leonardo Mina

Blood

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The Fanconi Anemia-Associated Protein NIPA Is Essential for the Nuclear Abundance of FANCD2

Detlev Schindler

Blood, 2019

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Clinical severity in Fanconi anemia correlates with residual function of FANCB missense variants

Filomena Pierri

2019

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Loss of the Fanconi anemia–associated protein NIPA causes bone marrow failure

Detlev Schindler

Journal of Clinical Investigation, 2020

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The Fanconi Anemia/BRCA pathway: new faces in the crowd

Richard Kennedy

Genes & Development, 2005

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FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

Arleen Auerbach

Nature structural & molecular biology, 2007

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The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma

Lindsey Romick-Rosendale

Mutation research

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Fancb deficiency impairs hematopoietic stem cell function

Paul Andreassen

Scientific reports, 2015

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The Fanconi anemia core complex associates with chromatin during S phase

Jun Mi

Blood, 2005

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A novel diagnostic screen for defects in the Fanconi anemia pathway

Akiko Shimamura

Blood, 2002

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MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM

Abdullah Ali

Molecular Cell, 2010

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Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein

Maurizio Mauro

2012

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Fanconi anemia proteins are required to maintain nucleolar homeostasis

Jean-jacques Diaz

2019

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The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation

Ahmed Suliman

Proceedings of the National Academy of Sciences of the United States of America, 1998

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Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia

Brijendra Singh

Nature communications, 2018

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Dysfunctional DNA repair pathway via defective FANCD2 gene engenders multifarious exomic and transcriptomic effects in Fanconi anemia

Natalie Fonville

Molecular Genetics & Genomic Medicine

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HES1 is a novel interactor of the Fanconi anemia core complex

Ouassila Habi

Blood, 2008

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Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability

Ricard Marcos

The EMBO Journal, 2007

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Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

maria jasin

Proceedings of The National Academy of Sciences, 2005

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Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin

Paul Andreassen

Blood, 2005

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Spectrum and significance of variants and mutations in the Fanconi anaemia group G gene in children with sporadic acute myeloid leukaemia

Jillian Birch

British Journal of Haematology, 2006

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Polygenic mutations model the pleiotropic disease of Fanconi Anemia

Detlev Schindler

bioRxiv (Cold Spring Harbor Laboratory), 2020

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Hypomorphic Mutations in the Gene Encoding a Key Fanconi Anemia Protein, FANCD2, Sustain a Significant Group of FA-D2 Patients with Severe Phenotype

Rosalina Van Spaendonk, Gerard Pals

The American Journal of Human Genetics, 2007

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Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway

ABDULLAH ALI

DNA Repair, 2011

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A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core …

Nobuko Matsushita

Molecular cell

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Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia

Tran Phuoc Nguyen B1703091

Blood cancer journal, 2018

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Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells

Marc Delord

Cell Stem Cell, 2012

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Milestones in Fanconi Anemia Research

K. Sperling

Monographs in Human Genetics, 2007

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A novel Leu153Ser mutation of the Fanconi anemia FANCD2 gene is associated with severe chemotherapy toxicity in a pediatric T-cell acute lymphoblastic leukemia

Valeria CONTI

Leukemia, 2006

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Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells

Atif siddique

Experimental hematology, 2001

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