Intracellular accumulation of the amyloidogenic L68Q variant of human cystatin C in NIH/3T3 cells (original) (raw)

Journal of Neuropathology and Experimental Neurology, 2001

Overexpression of Human Cystatin C in Transgenic Mice Does Not Affect Levels of Endogenous Brain Amyloid β Peptide

Journal of Molecular Neuroscience, 2004

Instability of the Amyloidogenic Cystatin C Variant of Hereditary Cerebral Hemorrhage with Amyloidosis, Icelandic Type

Journal of Biological Chemistry, 1998

Cystatin C modulates cerebral β-amyloidosis

Nature Genetics, 2007

Cystatin C inhibits amyloid-β deposition in Alzheimer's disease mouse models

Nature Genetics, 2007

The Role of Cystatin C in Cerebral Amyloid Angiopathy and Stroke: Cell Biology and Animal Models

Brain Pathology, 2006

Increased Cystatin C in Astrocytes of Transgenic Mice Expressing the K670N-M671L Mutation of the Amyloid Precursor Protein and Deposition in Brain Amyloid Plaques

Hasan Mohajeri

Neurobiology of Disease, 2001

Solubilized cystatin C amyloid is cytotoxic to cultured human cerebrovascular smooth muscle cells

Dadi Vilhjalmsson

Experimental and Molecular Pathology, 2007

Complexes of amyloid-β and cystatin C in the human central nervous system

2009

Involvement of cystatin C in pathophysiology of CNS diseases

Shotai Kobayashi

Frontiers in Bioscience, 2008

Alzheimer disease-associated cystatin C variant undergoes impaired secretion

Luisa Benussi

Neurobiology of Disease, 2003

On the role of monocytes/macrophages in the pathogenesis of central nervous system lesions in hereditary cystatin C amyloid angiopathy

Bjarni Asgeirsson

Journal of the Neurological Sciences, 1992

Interaction of serum amyloid A with human cystatin C-identification of binding sites

Anders Grubb, M. Maszota

Journal of Molecular Recognition, 2012

Cystatin C protects neuronal cells from amyloid-beta-induced toxicity

Elena Ribe

Journal of Alzheimer's disease : JAD, 2010

Genetic Association of a Cystatin C Gene Polymorphism With Late-Onset Alzheimer Disease

Luisa Benussi

Archives of Neurology, 2000

High throughput testing of drug library substances and monoclonal antibodies for capacity to reduce formation of cystatin C dimers to identify candidates for treatment of hereditary cystatin C amyloid angiopathy

Scandinavian Journal of Clinical & Laboratory Investigation, 2011

Biochemistry and Clinical Role of Human Cystatin C

Michele Mussap

Critical Reviews in Clinical Laboratory Sciences, 2004

Cystatin C binds serum amyloid A, downregulating its cytokine-generating properties

The Journal of rheumatology, 2007

Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 1996

Crystal structure of human cystatin C stabilized against amyloid formation

FEBS Journal, 2010

NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients

Alvaro Gutierrez-Uzquiza

Nature Communications

Increased body temperature accelerates aggregation of the Leu-68-->Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy

Proceedings of the National Academy of Sciences, 1994

Cystatin C in Alzheimer's disease

Frontiers in Molecular Neuroscience, 2012