Histopathological Study of Neoplastic Lesions of Oral Cavity (original) (raw)

Histopathological Study of Tumor and Tumor Like Lesions of the Oral Cavity

Annals of Pathology and Laboratory Medicine, 2019

Background: The oral cavity is one of the most common site for various tumor and tumor like lesions. Development of oral cavity lesions are strongly linked with smoking. Hemangioma is the commonest benign tumor. Inflammatory fibrous hyperplasia is the commonest nonneoplastic reactive lesion. Squamous cell carcinoma (SCC) is most common among malignant lesions. Aims & Objectives: To study the histopathological patterns & variations of oral cavity lesions. Materials and Methods: A three year retrospective cross-sectional study by histopathological examination. Results: A total of 105 cases were subjected to histopathological examination. Among these, 28 cases (26.66%) were benign, 27 cases (25.71%) were malignant and 4 cases (3.80%) were pre-malignant lesions. Among the malignant lesions, SCC was most common (85.19%), while inflammatory fibrous hyperplasiawas most common among non-neoplastic lesions (45.65 %). Overall females were affected more than males (M: F=1: 1.1), though malignant lesions were more common in males. Malignant lesions were more common in older age group (mean age 52.26%), while non-neoplastic lesions were common in younger age group (mean age 37.87%). Malignant lesions were most common intongue (11 cases, 40.74 %), while benign lesions were most common in gingiva (10cases, 35.71%). Conclusion: A variety of benign and malignant tumors occur in oral cavity. However, the origin and nature of the oral cavity lesions cannot be confirmed by clinical examination alone. Hence, histopathological examination is essential to confirm the diagnosis and malignant potential of the oral cavity lesions.

A Histopathological Study of Oral Cavity Lesions

https://www.ijhsr.org/IJHSR\_Vol.10\_Issue.3\_March2020/IJHSR\_Abstract.03.html, 2020

Background: Oral cavity is most common site for both non-neoplastic and neoplastic lesions. Most of the lesions are asymptomatic. Oral cancer is a major health problem in developing countries and hence it is important to examine precancerous lesion of oral cavity meticulously as they potentially develop into carcinomas. Objectives: To study various types of neoplastic and non-neoplastic lesions of oral cavity with reference to age, sex and site of lesion. Material and Methods: This was a prospective study carried out in a Department of Pathology, MGM medical College Kamothe, Navi Mumbai. Total 80 Cases oral cavity lesions were studied. Results: Out of 80 cases 24 (30%) were non-neoplastic and 56 (70%) were neoplastic lesions. Male predominance was seen in both the lesions. The most of the non-neoplastic lesions were seen in age group of 0-10 years and 21-30 years while neoplastic lesions were seen in 51-60 years of age group. Out of 56 Neoplastic lesions benign (12%), premalignant (29%), and malignant lesions (59%). Most common site of involvement in non-neopalstic lesion was palatine tonsils while majority of benign and premalignant lesions were seen in buccal mucosa (5% and 12% respectively). Tongue (20%) was the most common site for malignant lesions. Maximum cases of tonsillitis (14%) were seen in non-neoplastic lesions. Squamous cell carcinoma was seen in 39% of cases. Conclusion: Early detection of premalignant lesions can prevent further complication. Hence, not only clinical examination but also histopathological examination which is a gold standard for various lesions of oral cavity.

Histopathological Study of Oral Cavity Lesions

International Journal of Scientific Research, 2012

Histopathological Interpretation of Oral Cavity Lesions: Study at a Tertiary Care Hospital

IOSR Journals , 2019

Although the oral cavity lesions constitute only a small minority of pathological conditions, they are of great significance, as they have a potential to jeopardize the health and longevity of the patient. Among the various oral cavity lesions, oral cancer is a global health problem with increasing incidence and mortality rates. In India a vast majority of oral cancers are preceded by precancerous lesions & conditions caused by the use of tobacco in various forms. The aim of the present study is to know the spectrum and patterns of various oral cavity lesions at a tertiary care hospital, Ahmedabad, Gujarat, India. This is a one year study from June 2017 to May 2018. All the oral cavity specimens received in the Department of Pathology, GCS Hospital during the study period were included for the study. Data such as age, gender, and site of the lesion was collected. Data collected was analyzed. A total of 100 cases were analyzed during the study period. Age ranged from 2 to 78 years in the study. Overall male were affected more than the female with male:female (M:F) ratio of 3.5:1. Buccal mucosa (33%) was the commonest site involved followed by tongue (28%). Neoplastic lesions accounted for 69% cases and nonneoplastic accounted for 31% cases. Among the neoplastic lesion, squamous cell carcinoma (SCC) was seen in 40% cases; verrucous carcinoma in 6% and ameloblastic carcinoma in 1% cases; and adenosquamous carcinoma 1% cases. Most of the malignant lesions were located in the buccal mucosa (16%) and tongue (15%), followed by gingiva (6%),palate & floor of mouth (4%) each, lips (2%) alveolus (1%). Histology along with a detailed clinical work-up was found to be a useful, reliable and accurate diagnostic technique for lesions of oral cavity. A variety of lesions were encountered in the study with predominance of malignant lesions. Squamous cell carcinoma was the commonest malignant lesion.

Histopathological Audit of Oral Epithelial Lesions

2014

The objective of the study was to see the morphological pattern and frequency of oral epithelial lesions. All oral biopsies received in the Department of Pathology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre Karachi, over a period of 5 years were reviewed and relevant special stains were performed. A total of 685 cases were reviewed. Five hundred twelve (75%) were found neoplastic and 173 (25%) were non neoplastic. Granuloma Pyogenicum was the commonest (65) non neoplastic lesions. In neoplastic lesions, 498 cases were epithelial while 14 cases were diagnosed as non-epithelial lesions. Squamous cell carcinoma was found to be commonest (412 cases) epithelial malignant neoplastic lesion. There was a single case of benign epithelial lesion(Papilloma). The epithelial precursor lesions include 75(15%) cases of hyperplasia followed by 10(2%) showing mild dysplasia. Oral malignant epithelial lesions were common in 5th decade of life in males and 4th decade in fema...

The Spectrum of Oral Pathology Specimens: A Histopathologic Analysis of 442 Specimens

Jordan Medical Journal

Background Aims: Diseases of the oral cavity are heterogenous regarding their etiology, pathogenesis, histogenesis and clinical outcomes. The aim of this study was to examine the frequency of oral diseases encountered in our experience. Methods: The archives of pathology at Jordan University Hospital were retrospectively searched for oral cavity specimens from 2013–2020. Fisher’s exact test was performed to examine the statistical difference between the pathologic diagnosis and clinical variables. One-way ANOVA was used to analyze the differences in the mean of age between the different pathologic groups. Results: A total of four-hundred and forty-two cases were retrieved. There were 232 (52%) females and 210 (48%) males, ranging in age from 3–87 years (mean 43). Inflammatory and reactive diseases were the most common, constituting 147 (33%) of all specimens, followed by 139 (31%) benign neoplasms, 114 (26%) cysts, and 42 (10%) malignant diseases. Lichen planus was the most common i...

Correlation between Clinical and Histopathological Diagnoses in Oral Cavity Lesions: A 12-Year Retrospective Study

International Journal of Dentistry

Objective. Proper diagnosis plays a key role in the treatment and prognosis of all diseases. Although histopathological diagnosis is still known as the gold standard, final diagnosis becomes difficult unless precise clinical descriptions are obtained. So, this study aimed to evaluate the concordance of the clinical and histopathological diagnoses of all oral and maxillofacial biopsy specimens in a 12-year duration. Materials and Methods. Archive files and clinical findings related to 3001 patients who had been referred to the Department of Oral Pathology during a 12-year period were reviewed. The recorded information in files included age, sex, lesion’s location, clinical and histopathological diagnoses, and specialty of dentists. Results. Out of 3001 cases included and reviewed in this study, 2167 cases (72.2%) were consistent between clinical and histopathologic diagnoses. Age, sex, and clinician’s specialty were indicated to have no significant effect on diagnosis (p values = 0.5...

Tumour-like lesions of oral cavity: A clinicopathological study of 95 cases

Annals of Applied Bio-Sciences, 2017

Background: Tumourlike lesions or reactive lesions of the oral cavity are group of fibroconnective tissue lesions that commonly occur in the oral mucosa as a result of injury. Aim: The purpose of this study is to determine the relative prevalence of different histopathological aspects of oral soft tissue tumourlike lesions which were received at Pathology department, Government medical college, Miraj, Maharashtra Methods: A total number of 95 cases of tumourlike lesions were included in the study. Specimens were received at department of pathology, Government medical college, Miraj, Maharashtra over a period of 5 years from August 2008 to July 2013. It was one year retrospective and four years prospective, cross sectional study Result: A total number of 642 oral biopsies and excised specimens were studied, out of which 95cases (14.8%) belonged to tumourlike lesions. Among tumorlike lesions, pyogenic granuloma (47.38%) was the commonest lesion, followed by Mucocele (26.32%). Majority of tumorlike lesions were located on gingiva (38.94%) followed by lower lip (28.42%). Males (57.89%) were more commonly affected than females and the commonest symptom was swelling (100%). Conclusion: The most common tumourlike lesion in our study was pyogenic granuloma. Few very rare and interesting cases like plasma cell granuloma and Nasolabial cyst were also seen. Tumorlike lesions presented mainly as nodule or swelling, which should be differentiated from other benign and sometimes malignant lesions, as the tumourlike lesions have good prognosis when compared to malignant lesions. Hence histopathology remains the mainstay for correct diagnosis and treatment.

Profile of oral cavity neoplastic lesions: two year pilot study at tertiary care centre

International Journal of Otorhinolaryngology and Head and Neck Surgery

Background: In India 53,251 new head and neck cancer cases are diagnosed every year. Benign tumours are more frequently in the oral cavity than oropharynx.Methods: The prospective study was carried out in the Department of Otolaryngology and Head and Neck Surgery, Dayanand Medical College and Hospital, Ludhiana, over a period of two and half years, comprised of 66 cases of head and neck neoplasia. The demographic, gender profile, clinical presentation, histopathological diagnosis, therapeutic modality undertaken and post op complications of neoplastic lesions of the oral cavity were studied. follow up was done for 6 months. The therapeutic modalities included surgery, radiotherapy and chemotherapy as per the stage of the lesion.Results: Incidence of oral cancer is 13.6% among head and neck neoplasms over a period of 2 years (2011-2012). The overall male to female ratio was 1:1.25, among benign was 1:1 and among malignant was 1:1.3. Benign oral cavity tumors were managed surgically w...

Agreement between clinical and histopathological diagnoses of oral lesions

RGO.Revista Gaúcha de Odontologia (Online), 2010

The present study aimed to assess the rate of agreement between clinical and histopathological diagnoses and to report the frequency of completed forms for specimens that were subjected to histopathological examination and retrospectively examined. Data from 8,168 specimens submitted to histopathological examination were retrieved from the records. A total of 5,368 cases were included. Agreement was defined based on the definition of lesion nature according to its diagnostic category. Sensitivity, specificity, and positive and negative predictive values were calculated for each diagnostic category. The highest rate of agreement was observed for periapical lesions (92.6%), followed by potentially malignant disorders (90.1%) and non-neoplastic proliferative disorders (89.3%). Low rates of histopathological confirmation of the clinical impression were observed for mesenchymal tumors (25.0%) and cysts (44.2%). Sensitivity values were > 0.70 for all lesions, except for cysts (0.51). Specificity was relatively high, ranging from 0.97 to 1.00. The frequency of incomplete biopsy forms ranged from 16.8% (malignant tumors of oral mucosal epithelium) to 51.0% (nonspecific inflammatory reaction). The most frequently completed biopsy forms corresponded to epithelial malignant tumors (83.2%) and glandular inflammation (72.3%). In conclusion, there was an acceptable level of agreement. The low level of completeness of biopsy forms indicates little awareness about the relevance of gathering detailed information during clinical examination.

Histopathological Study of Neoplastic Lesions of Oral Cavity (original) (raw)

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