Evaluation of the effects of specific opioid receptor agonists in a rodent model of spinal cord injury (original) (raw)
Morphine Undermines Recovery Following Spinal Cord Injury: Evaluation of Opioid Receptors and Cellular Mechanisms
Miriam Aceves
2017
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Neurobiological Effects of Morphine after Spinal Cord Injury
Eric Bancroft
Journal of Neurotrauma, 2017
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Morphine can produce analgesia via spinal kappa opioid receptors in the absence of mu opioid receptors
Naohito Shimoyama
Brain Research, 2006
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Nor-Binaltorphimine Blocks the Adverse Effects of Morphine after Spinal Cord Injury
Miriam Aceves
Journal of Neurotrauma, 2017
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The impact of morphine after a spinal cord injury
Michelle Hook
Behavioural Brain Research, 2007
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Direct evidence for the up-regulation of spinal u-opioid receptor function after repeated stimulation of kappa-opioid receptors in the mouse
Junaidi Khotib
European Journal of Neuroscience, 2003
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Opioid regulation of spinal cord plasticity: Evidence the kappa-2 opioid receptor agonist GR89696 inhibits learning within the rat spinal cord
James Grau
Neurobiology of Learning and Memory, 2008
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Inhibition of morphine-induced analgesia and locomotor activity in strains of mice: A comparison of long-acting opiate antagonists
Bert Siegfried
Pharmacology Biochemistry and Behavior, 1983
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Adam F, Dufour E, Le Bars D D (2008) The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism. Neuropharmacology 54 : 588-596.
daniel le bars
Neuropharmacology, 2008
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Opioid and substance p receptor adaptations in the rat spinal cord following sub-chronic intrathecal treatment with morphine and naloxone
Ruth Cridland
Neuroscience, 1993
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Antinociceptive and Adverse Effects of µ- and κ-Opioid Receptor Agonists: A Comparison of Morphine and U50488-H
Theo Meert
Basic & Clinical Pharmacology & Toxicology, 2008
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Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level
Javier Garzón
British Journal of Pharmacology, 2012
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Pre-injury administration of morphine prevents development of neuropathic hyperalgesia through activation of descending monoaminergic mechanisms in the spinal cord in mice
Hiroshi Ueda
Molecular pain, 2005
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Analgesia or Addiction?: Implications for Morphine Use after Spinal Cord Injury
Michelle Hook
Journal of Neurotrauma, 2012
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Chronic opioid antagonist treatment selectively regulates trafficking and signaling proteins in mouse spinal cord
KAUSHAL PATEL
Synapse, 2003
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The kappa-opioid receptor is upregulated in the spinal cord and locus ceruleus but downregulated in the dorsal root ganglia of morphine tolerant rats
li sun
Brain Research, 2010
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Moxonidine, a Selective Imidazoline–α2-Adrenergic Receptor Agonist, Produces Spinal Synergistic Antihyperalgesia with Morphine in Nerve-injured Mice
Kelley Kitto
Anesthesiology, 2000
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Ketamine blocks enhancement of spinal long-term potentiation in chronic opioid treated rats
A. Tjølsen
Acta Anaesthesiologica Scandinavica, 2008
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Morphine-6-glucuronide-Induced Locomotor Stimulation in Mice: Role of Opioid Receptors
Marte Handal
Pharmacology & Toxicology, 1998
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Spinal Glucocorticoid Receptors Contribute to the Development of Morphine Tolerance in Rats
Backil Sung
Anesthesiology, 2005
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Intrathecal Morphine Attenuates Recovery of Function after a Spinal Cord Injury
Michelle Hook
Journal of Neurotrauma, 2009
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A role for heterodimerization of µ and opiate receptors in enhancing morphine analgesia
lakshmi devi
Proceedings of The National Academy of Sciences, 2004
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Morphine Tolerance in Spinal Cord Is Due to Interaction between micro- and delta -Receptors
Pal Riba
Journal of Pharmacology and Experimental Therapeutics, 2002
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The Effects of Repeated Opioid Administration on Locomotor Activity: I. Opposing Actions of μ and κ Receptors
Mark Smith
Journal of Pharmacology and Experimental Therapeutics, 2009
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MOL-13185 1 Morphine-induced µ-opioid receptor desensitization MOL-13185 2 a. Running title Morphine-induced desensitization
Vu Dang
2020
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Experimental considerations for the assessment of in vivo and in vitro opioid pharmacology
Rob Hill
Pharmacology & Therapeutics, 2021
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The loss of antinociceptive efficacy of spinal morphine in rats with nerve ligation injury is prevented by reducing spinal afferent drive
Michael Ossipov
Neuroscience Letters, 1995
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Opioid Agonists Differentially Regulate μ-Opioid Receptors and Trafficking Proteins in Vivo
Dr Minesh Patel
Molecular Pharmacology, 2002
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Opioid administration following spinal cord injury: Implications for pain and locomotor recovery
Michelle Hook
Experimental Neurology, 2013
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Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice
Richard Hunter
Brain Research, 2004
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Effect of κ-opioid receptor agonists on morphine analgesia in morphine-naive and morphine-tolerant rats
ramarao poduri
European Journal of Pharmacology, 1988
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Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers
Michael Ossipov
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002
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Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin
Michael Ossipov
Pain, 2001
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The Role of Spinal Opioid Receptors in Antinociceptive Effects Produced by Intrathecal Administration of Hydromorphone and Buprenorphine in the Rat
Anil Rattan
Anesthesia & Analgesia, 2002
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Chronic treatment with the opioid antagonist naltrexone favours the coupling of spinal cord μ-opioid receptors to Gαz protein subunits
alvaro diaz
Neuropharmacology, 2012
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