Direct evidence for the up-regulation of spinal u-opioid receptor function after repeated stimulation of kappa-opioid receptors in the mouse (original ) (raw )Heterologous µ-opioid receptor adaptation by repeated stimulation of κ-opioid receptor: up-regulation of G-protein activation and antinociception: Up-regulation of µ-opioid receptor function
Junaidi Khotib
Journal of Neurochemistry, 2003
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Heterologous µ-opioid receptor adaptation by repeated stimulation of κ-opioid receptor: up-regulation of G-protein activation and antinociception
Junaidi Khotib
Journal of Neurochemistry, 2003
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Journal of Neuroscience Research, 2009
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Miriam Aceves
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KAUSHAL PATEL
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L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective μ opioid agonist, but not to selective δ and κ agonist at the level of the spinal cord in mice
Ahmet Dogrul
Pain, 2001
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Morphine can produce analgesia via spinal kappa opioid receptors in the absence of mu opioid receptors
Naohito Shimoyama
Brain Research, 2006
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Spinal opioid analgesia: how critical is the regulation of substance P signaling?
Serge Marchand
The Journal of …, 1999
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Biochemical characterization and regional quantification of μ, δ and κ opioid binding sites in rat spinal cord
V. Seybold , Robert Elde
Brain Research, 1991
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Antagonist-induced μ-opioid receptor up-regulation decreases G-protein receptor kinase-2 and dynamin-2 abundance in mouse spinal cord
Dr Minesh Patel
European Journal of Pharmacology, 2002
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Different μ receptor subtypes mediate spinal and supraspinal analgesia in mice
Richard Bodnar , Dennis Paul
European Journal of Pharmacology, 1989
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Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level
Javier Garzón
British Journal of Pharmacology, 2012
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Lack of μ-Opioid Receptor-Mediated G-Protein Activation in the Spinal Cord of Mice Lacking Exon 1 or Exons 2 and 3 of the MOR-1 Gene
Scott Hall
Journal of Pharmacological Sciences, 2003
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Kappa-Opioid Receptor Agonists Modulate Excitatory Transmission in Substantia Gelatinosa Neurons of the Rat Spinal Cord
Luba Kojic
The Journal of Neuroscience, 1995
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[d-Ala2,N-MePhe4,Gly-ol5]enkephalin-induced internalization of the μ opioid receptor in the spinal cord of morphine tolerant rats
Jodie Trafton
Neuroscience, 2004
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Neuropathic Pain Activates the Endogenous Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance
Jay Malan
Journal of Neuroscience, 2004
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Michael Ossipov
Pain, 2001
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Opioid regulation of spinal cord plasticity: Evidence the kappa-2 opioid receptor agonist GR89696 inhibits learning within the rat spinal cord
James Grau
Neurobiology of Learning and Memory, 2008
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Michael Ossipov , Todd Vanderah
Pain, 2002
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A study of the antinociceptive interaction between intrathecal opioids and α-adrenergic agonists in the spinal cord of the rat
John Axcel Bautista
1996
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Stimulus intensity and the comparative efficacy of ω- and κ-opioid agonists on nociceptive spinal reflexes in the rat
Juan Herrero
Brain Research, 1994
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Selective impairment of spinal mu-opioid receptor mechanism by plasticity of serotonergic facilitation mediated by 5-HT2A and 5-HT2B receptors
Monika Salgueiro
Pain, 2012
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Acute and Chronic Effects of Opioids on δ and μ Receptor Activation of G Proteins in NG108-15 and SK-N-SH Cell Membranes
Christopher Breivogel
Journal of Neurochemistry, 2002
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к-Opioid receptor stimulation abolishes μ- but not δ-mediated inhibitory control of spinal Met-enkephalin release
E. Collin
Neuroscience Letters, 1992
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KAPPA-/MU-receptor interactions in the opioid control of the in vivo release of substance P-like material from the rat spinal cord
lotfi ferhat
Neuroscience, 1992
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Opioid and substance p receptor adaptations in the rat spinal cord following sub-chronic intrathecal treatment with morphine and naloxone
Ruth Cridland
Neuroscience, 1993
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Activity of the δ-opioid receptor is partially reduced, whereas activity of the κ-receptor is maintained in mice lacking the μ-receptor
R. Maldonado
1998
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Spinal L-Type Calcium Channel Blockade Abolishes Opioid-Induced Sensory Hypersensitivity and Antinociceptive Tolerance
Michael Ossipov
Anesthesia & Analgesia, 2005
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Different Regulation of Human δ-Opioid Receptors by SNC-80 [(+)-4-[(αR )-α-((2S ,5R )-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N ,N -diethylbenzamide] and Endogenous Enkephalins
stephane allouche
Journal of Pharmacology and Experimental Therapeutics, 2004
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Studies on spinal opiate receptor pharmacology. III. Analgetic effects of enkephalin dimers as measured by cutaneous-thermal and visceral-chemical evoked responses
David Rodbard
Brain Research, 1985
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Upregulation of an opioid-mediated antinociceptive mechanism in transgenic mice over-expressing substance P in the spinal cord
A.C. Cuello
Neuroscience, 2000
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Curre T K Owledge a D Future Tre DS of e Doge Ous Opioids: Their Physiological Role a D Receptors
shaik rizwan
2010
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