Direct evidence for the up-regulation of spinal u-opioid receptor function after repeated stimulation of kappa-opioid receptors in the mouse (original) (raw)

Heterologous µ-opioid receptor adaptation by repeated stimulation of κ-opioid receptor: up-regulation of G-protein activation and antinociception: Up-regulation of µ-opioid receptor function

Junaidi Khotib

Journal of Neurochemistry, 2003

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Heterologous µ-opioid receptor adaptation by repeated stimulation of κ-opioid receptor: up-regulation of G-protein activation and antinociception

Junaidi Khotib

Journal of Neurochemistry, 2003

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Effects of acute agonist treatment on subcellular distribution of κ opioid receptor in rat spinal cord

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KAUSHAL PATEL

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L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective μ opioid agonist, but not to selective δ and κ agonist at the level of the spinal cord in mice

Ahmet Dogrul

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Morphine can produce analgesia via spinal kappa opioid receptors in the absence of mu opioid receptors

Naohito Shimoyama

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Serge Marchand

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Biochemical characterization and regional quantification of μ, δ and κ opioid binding sites in rat spinal cord

V. Seybold, Robert Elde

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Antagonist-induced μ-opioid receptor up-regulation decreases G-protein receptor kinase-2 and dynamin-2 abundance in mouse spinal cord

Dr Minesh Patel

European Journal of Pharmacology, 2002

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Different μ receptor subtypes mediate spinal and supraspinal analgesia in mice

Richard Bodnar, Dennis Paul

European Journal of Pharmacology, 1989

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Javier Garzón

British Journal of Pharmacology, 2012

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Scott Hall

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Kappa-Opioid Receptor Agonists Modulate Excitatory Transmission in Substantia Gelatinosa Neurons of the Rat Spinal Cord

Luba Kojic

The Journal of Neuroscience, 1995

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[d-Ala2,N-MePhe4,Gly-ol5]enkephalin-induced internalization of the μ opioid receptor in the spinal cord of morphine tolerant rats

Jodie Trafton

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Neuropathic Pain Activates the Endogenous Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance

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James Grau

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A study of the antinociceptive interaction between intrathecal opioids and α-adrenergic agonists in the spinal cord of the rat

John Axcel Bautista

1996

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Stimulus intensity and the comparative efficacy of ω- and κ-opioid agonists on nociceptive spinal reflexes in the rat

Juan Herrero

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Selective impairment of spinal mu-opioid receptor mechanism by plasticity of serotonergic facilitation mediated by 5-HT2A and 5-HT2B receptors

Monika Salgueiro

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Acute and Chronic Effects of Opioids on δ and μ Receptor Activation of G Proteins in NG108-15 and SK-N-SH Cell Membranes

Christopher Breivogel

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к-Opioid receptor stimulation abolishes μ- but not δ-mediated inhibitory control of spinal Met-enkephalin release

E. Collin

Neuroscience Letters, 1992

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KAPPA-/MU-receptor interactions in the opioid control of the in vivo release of substance P-like material from the rat spinal cord

lotfi ferhat

Neuroscience, 1992

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Opioid and substance p receptor adaptations in the rat spinal cord following sub-chronic intrathecal treatment with morphine and naloxone

Ruth Cridland

Neuroscience, 1993

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Activity of the δ-opioid receptor is partially reduced, whereas activity of the κ-receptor is maintained in mice lacking the μ-receptor

R. Maldonado

1998

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Spinal L-Type Calcium Channel Blockade Abolishes Opioid-Induced Sensory Hypersensitivity and Antinociceptive Tolerance

Michael Ossipov

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Studies on spinal opiate receptor pharmacology. III. Analgetic effects of enkephalin dimers as measured by cutaneous-thermal and visceral-chemical evoked responses

David Rodbard

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Upregulation of an opioid-mediated antinociceptive mechanism in transgenic mice over-expressing substance P in the spinal cord

A.C. Cuello

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Curre T K Owledge a D Future Tre DS of e Doge Ous Opioids: Their Physiological Role a D Receptors

shaik rizwan

2010

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