EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus–infected B cells (original) (raw)

The EBNA2-EBF1 complex promotes oncogenic MYC expression levels and metabolic processes required for cell cycle progression of Epstein-Barr virus-infected B cells

Lucas Wange

2021

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Identification of Epstein-Barr Virus (EBV) Nuclear Antigen 2 (EBNA2) Target Proteins by Proteome Analysis: Activation of EBNA2 in Conditionally Immortalized B Cells Reflects Early Events after Infection of Primary B Cells by EBV

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Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth

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EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells

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The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold

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Epstein-Barr virus nuclear protein EBNA3C directly induces expression of AID and somatic mutations in B cells

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Role of EBNA-3 Family Proteins in EBV Associated B-cell Lymphomagenesis

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Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid Cells

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Phosphorylation sites of Epstein-Barr virus EBNA1 regulate its function

Dick Burgess

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Functional Analyses of the EBNA1 Origin DNA Binding Protein of Epstein-Barr Virus

Derek Ceccarelli

Journal of Virology, 2000

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Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2

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Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency

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Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival

cj mancao

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Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth

ANDREW Cooper

Journal of Virology, 2003

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Potential Cellular Functions of Epstein-Barr Nuclear Antigen 1 (EBNA1) of Epstein-Barr Virus

Bill Sugden

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Transcription Profiling of Epstein-Barr Virus Nuclear Antigen (EBNA)-1 Expressing Cells Suggests Targeting of Chromatin Remodeling Complexes

Maria Masucci

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The amino terminus of Epstein-Barr Virus (EBV) nuclear antigen 1 contains AT hooks that facilitate the replication and partitioning of latent EBV genomes by tethering them to cellular chromosomes

John Sears

Journal of Virology, 2004

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Conserved cell cycle regulatory properties within the amino terminal domain of the Epstein–Barr virus nuclear antigen 3C

NIKHIL SHARMA

Virology, 2006

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Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)

Louise Showe

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Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A

Arthur Shaffer

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Epstein-Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth

S. Tobollik

Blood, 2006

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Epstein-Barr virus EBNA3A and EBNA3C proteins both repress RBP-J kappa-EBNA2-activated transcription by inhibiting the binding of RBP-J kappa to DNA

Evelyne Manet

Journal of virology, 1996

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A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism

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Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Barr Virus Antagonizes Transforming Growth Factor 1-Induced B-Cell Apoptosis

Eva Campion

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EBNA2 Is Required for Protection of Latently Epstein-Barr Virus-Infected B Cells against Specific Apoptotic Stimuli

Christopher Farrell

Journal of Virology, 2004

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Epstein-Barr virus latent membrane protein 2A mimics B-cell receptor-dependent virus reactivation

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Identification of MEF2B, EBF1, and IL6R as direct gene targets of EBNA1 critical for EBV-infected B-lymphocyte survival

Alessandra De Leo

Journal of virology, 2015

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EBV genome carrying B lymphocytes that express the nuclear protein EBNA-2 but not LMP-1

Abu Rasul, Eva Klein

OncoImmunology, 2013

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Interaction of Epstein-Barr virus (EBV) with human B-lymphocytes

Eva Klein

Biochemical and Biophysical Research Communications, 2010

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