Putting on the Brakes: Regulatory Kinases and Phosphatases Maintaining B Cell Anergy
John Cambier
Frontiers in Immunology, 2018
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B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens
John Cambier
Journal of autoimmunity, 2015
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Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells
John Cambier
The Journal of experimental medicine, 2016
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Differential Regulation of B Cell Development, Activation, and Death by the Src Homology 2 Domain-containing 5 9 Inositol Phosphatase (SHIP
Idan Tamir, John Cambier
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Differential Regulation of B Cell Development, Activation, and Death by the Src Homology 2 Domain–Containing 5′ Inositol Phosphatase (Ship)
John Cambier
The Journal of Experimental Medicine, 2000
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A Dual Role for Src Homology 2 Domain-Containing Inositol-5-Phosphatase (Ship) in Immunity: Aberrant Development and Enhanced Function of B Lymphocytes in Ship-/- Mice
Nicolas Pineault
Journal of Experimental Medicine, 2000
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Molecular underpinning of B-cell anergy
Yuval Yarkoni
Immunological Reviews, 2010
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The Inositol Polyphosphate 5Phosphatase Ship Is a Crucial Negative Regulator of B Cell Antigen Receptor Signaling
Jamie Jones
2010
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Enhanced Tyrosine Phosphatase Activity Underlies Dysregulated B-cell Receptor Signaling and Promotes Survival of Human Lupus B-cells
Capucine Daridon
Arthritis & Rheumatology, 2015
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Distribution of the Src-homology-2-domain-containing inositol 5-phosphatase SHIP2 in both non-haemopoietic and haemopoietic cells and possible involvement of SHIP2 in negative signalling of B-cells
Eric Muraille
Biochemical Journal, 1999
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Anergic B Cells: Precarious On-Call Warriors at the Nexus of Autoimmunity and False-Flagged Pathogens
Allen Rosenspire
Frontiers in Immunology, 2015
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Receptors, subcellular compartments and the regulation of peripheral B cell responses: The illuminating state of anergy
Sarah Powers
Molecular Immunology, 2011
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The Structural Wedge Domain of the Receptor-like Tyrosine Phosphatase CD45 Enforces B Cell Tolerance by Regulating Substrate Specificity
Arthur Weiss
The Journal of Immunology, 2013
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Signaling mechanisms regulating B-lymphocyte activation and tolerance
Elias Hobeika, Thomas Nielsen, D. Medgyesi
Journal of Molecular Medicine, 2015
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Aberrant antibody affinity selection in SHIP-deficient B cells
Silvia Bolland
European Journal of Immunology, 2013
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SHP1 upon Tyrosine Phosphorylation CD72 Recruits the Tyrosine Phosphatase Cutting Edge: The B Cell Surface Protein
Michael Reth
2000
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Low-Affinity Anti-Smith Antigen B Cells Are Regulated by Anergy as Opposed to Developmental Arrest or Differentiation to B-1
Michelle Borrero Sierra
The Journal of Immunology, 2002
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B lymphocyte signaling pathways in systemic autoimmunity: Implications for pathogenesis and treatment
Gabriella Sarmay
Arthritis & Rheumatism, 2004
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A Balance between B Cell Receptor and Inhibitory Receptor Signaling Controls Plasma Cell Differentiation by Maintaining Optimal Ets1 Levels
Thomas Tedder
The Journal of Immunology, 2014
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Integration of activatory and inhibitory signals in human B-cells
Gabriella Sarmay
Immunology Letters, 1996
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Recruitment and phosphorylation of SH2-containing inositol phosphatase and Shc to the B-cell Fc gamma immunoreceptor tyrosine-based inhibition motif peptide motif
Madhura Pradhan, Damon Cooney
Molecular and cellular biology, 1997
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Inhibitory Modulation of B Cell Receptor-mediated Ca2+ Mobilization by Src Homology 2 Domain-containing Inositol 5′-Phosphatase (SHIP)
Masamitsu Iino
Journal of Biological Chemistry, 1999
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SHIP Recruitment Attenuates FcγRIIB-Induced B Cell Apoptosis
Silvia Bolland
Immunity, 1999
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Dysfunctional B cells in systemic lupus erythematosus
Christophe Jamin, Yves Renaudineau, Jacques-olivier Pers
Autoimmunity Reviews, 2004
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Transmodulation of BCR signaling by transduction-incompetent antigen receptors: implications for impaired signaling in anergic B cells
Barbara Vilen
Journal of immunology (Baltimore, Md. : 1950), 2002
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Cutting Edge: Role of the Inositol Phosphatase SHIP in B Cell Receptor Induced Ca 21 Oscillatory Response1
Silvia Bolland
The Journal of Immunology
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Cutting Edge: Role of the Inositol Phosphatase SHIP in B Cell Receptor-Induced Ca2+ Oscillatory Response
Silvia Bolland
The Journal of Immunology, 1998
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Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors
Kristi Koelsch
Journal of Experimental Medicine, 2009
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The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcγRIIB and is mandatory for negative regulation of B cell activation
Is Isnardi
Immunology Letters, 2006
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Cbl-b Negatively Regulates B Cell Antigen Receptor Signaling in Mature B Cells through Ubiquitination of the Tyrosine Kinase Syk
Hua Gu
Journal of Experimental Medicine, 2003
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The SH2 domain containing inositol 5-phosphatase SHIP2 associates to the immunoreceptor tyrosine-based inhibition motif of FcγRIIB in B cells under negative signaling
Eric Muraille
Immunology Letters, 2000
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Regulation of the B Cell Receptor Repertoire
Takayuki Ota
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Anti-CD79 Antibody Induces B Cell Anergy That Protects against Autoimmunity
Giovanni Magistrelli, Walter Reith
The Journal of Immunology, 2014
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Characterization of anergic anti-DNA B cells: B cell anergy is a T cell-independent and potentially reversible process
Anh Quy Bui
International Immunology, 1999
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Response Oscillatory 2+ Receptor-Induced Ca Phosphatase SHIP in B Cell Cutting Edge: Role of the Inositol
Silvia Bolland
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