The imidazoline derivative calmidazolium inhibits voltage-gated Ca2+-channels and insulin release but has no effect on the phospholipase C system in insulin producing RINm5F-cells (original) (raw)

Calmodulin inhibits inositol trisphosphate-induced Ca2+ mobilization from the endoplasmic reticulum of islets

Jerry Colca

Biochemical and Biophysical Research Communications, 1986

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Ca2+-calmodulin inhibits Ca2+ release mediated by type-1, -2 and -3 inositol trisphosphate receptors

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Biochemical Journal, 2000

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Calmodulin inhibits inositol 1,4,5‐trisphosphate‐induced calcium release through the purified and reconstituted inositol 1,4,5‐trisphosphate receptor type 1

Takayuki Michikawa

FEBS Letters, 1999

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Imidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinery

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Diabetes, 1996

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Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells

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Ca2+-independent inhibition of inositol trisphosphate receptors by calmodulin: Redistribution of calmodulin as a possible means of regulating Ca2+ mobilization

Sandip Patel

Proceedings of the National Academy of Sciences, 1997

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Calmodulin levels in diabetic mice

Allen Levine

Biochemical and Biophysical Research Communications, 1982

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The Role of Calcium and Calmodulin in Insulin Receptor Function in the Adipocyte

Jerry Colca

Annals of the New York Academy of Sciences, 1986

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Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release

Paul Squires

British Journal of Pharmacology, 1996

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The uses and limitations of calmodulin antagonists

W David Sedwick

Pharmacology & Therapeutics, 1989

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The role of calmodulin for inositol 1,4,5-trisphosphate receptor function

Ilse Sienaert

Biochimica Et Biophysica Acta-proteins and Proteomics, 2002

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Activation of calcium and calmodulin dependent protein kinase II during stimulation of insulin secretion

Jerry Colca

Cell Calcium, 1994

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Correlation of Ca2+-and calmodulin-dependent protein kinase activity with secretion of insulin from islets of Langerhans

Jerry Colca

The Biochemical journal, 1983

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Stimulation of insulin release from the MIN6 cell line by a new imidazoline compound, S-21663: evidence for the existence of a novel imidazoline site in β cells

Anne Virsolvy

British Journal of Pharmacology, 1997

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Calmodulin as a mediator of hormone action and cell regulation

Lisette Lagace

Journal of Cellular Biochemistry, 1982

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Insulin stimulates the phosphorylation of calmodulin in intact adipocytes

Jerry Colca

Journal of Biological Chemistry

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Ca2+/calmodulin-dependent protein kinase II δ2 regulates gene expression of insulin in INS-1 rat insulinoma cells

Martin Osterhoff

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Alloxan inhibition of a Ca2+- and calmodulin-dependent protein kinase activity in pancreatic islets

Jerry Colca

Journal of Biological Chemistry

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Regulation of pancreatic islet-cell plasma membrane Ca2+ + Mg2+-ATPase by Calmodulin

Jerry Colca

FEBS Letters, 1982

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Functional in vitro test of calmodulin antagonism: effect of drugs on interaction between calmodulin and glycolytic enzymes

Ferenc Orosz

Molecular pharmacology, 1988

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Potassium Channels, Imidazolines, and Insulin-Secreting Cells

Paul Squires

Annals of the New York Academy of Sciences, 1995

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PHARMACOLOGICAL REGULATION OF CALMODULIN*

Benjamin Weiss

Annals of the New …, 1980

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Effect of calmidazolium on Ca2+ movement and proliferation in human osteosarcoma cells

Bang-Ping Jiann

Clinical and Experimental Pharmacology and Physiology, 2004

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Depolarizing Stimuli Reduce Ca2+/Calmodulin-Dependent Protein Kinase II Activity in Islets of Langerhans

Paul Squires

Biochemical and Biophysical Research Communications, 2000

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The Imidazoline RX871024 Stimulates Insulin Secretion in Pancreatic β-Cells from Mice Deficient in KATP Channel Function

Mark A Magnuson

Biochemical and Biophysical Research Communications, 2001

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Phospholipid-sensitive Ca2+-dependent protein kinase inhibition by R-24571, a calmodulin antagonist

Raymond S Turner

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Phosphorylation of calmodulin. Functional implications

Gustavo Benaim

European Journal of Biochemistry

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Calmodulin and its role in intracellular calcium regulation

J.-c. Stoclet

Progress in Neurobiology, 1987

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Phosphorylation of calmodulin

Gustavo Benaim

European Journal of Biochemistry, 2002

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Calmodulin in endocrine cells and its multiple roles in hormone action

Anthony Means

Molecular and Cellular Endocrinology, 1980

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Ca2+-Calmodulin-dependent Facilitation and Ca2+ Inactivation of Ca2+ Release-activated Ca2+ Channels

Sebastian Straube

Journal of Biological Chemistry, 2005

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Calcium-dependent binding of calmodulin to phospholipase A2 subunits induces enzymatic activation

Walter Silva

Archives of Biochemistry and Biophysics, 1985

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Calmodulin content and in vitro contractility of duodenum from streptozotocin-induced diabetic rats: effects of insulin therapy and calmodulin antagonism

Yusuf Öztürk

European Journal of Pharmacology, 1997

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