The imidazoline derivative calmidazolium inhibits voltage-gated Ca2+-channels and insulin release but has no effect on the phospholipase C system in insulin producing RINm5F-cells (original ) (raw )Calmodulin inhibits inositol trisphosphate-induced Ca2+ mobilization from the endoplasmic reticulum of islets
Jerry Colca
Biochemical and Biophysical Research Communications, 1986
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Ca2+-calmodulin inhibits Ca2+ release mediated by type-1, -2 and -3 inositol trisphosphate receptors
Ilse Sienaert
Biochemical Journal, 2000
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Calmodulin inhibits inositol 1,4,5‐trisphosphate‐induced calcium release through the purified and reconstituted inositol 1,4,5‐trisphosphate receptor type 1
Takayuki Michikawa
FEBS Letters, 1999
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Imidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinery
Garry Gold
Diabetes, 1996
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Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells
Martin Bootman , F. McDonald
Biochemical Journal, 2004
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Ca2+-independent inhibition of inositol trisphosphate receptors by calmodulin: Redistribution of calmodulin as a possible means of regulating Ca2+ mobilization
Sandip Patel
Proceedings of the National Academy of Sciences, 1997
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Calmodulin levels in diabetic mice
Allen Levine
Biochemical and Biophysical Research Communications, 1982
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The Role of Calcium and Calmodulin in Insulin Receptor Function in the Adipocyte
Jerry Colca
Annals of the New York Academy of Sciences, 1986
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Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release
Paul Squires
British Journal of Pharmacology, 1996
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The uses and limitations of calmodulin antagonists
W David Sedwick
Pharmacology & Therapeutics, 1989
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The role of calmodulin for inositol 1,4,5-trisphosphate receptor function
Ilse Sienaert
Biochimica Et Biophysica Acta-proteins and Proteomics, 2002
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Activation of calcium and calmodulin dependent protein kinase II during stimulation of insulin secretion
Jerry Colca
Cell Calcium, 1994
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Correlation of Ca2+-and calmodulin-dependent protein kinase activity with secretion of insulin from islets of Langerhans
Jerry Colca
The Biochemical journal, 1983
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Stimulation of insulin release from the MIN6 cell line by a new imidazoline compound, S-21663: evidence for the existence of a novel imidazoline site in β cells
Anne Virsolvy
British Journal of Pharmacology, 1997
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Calmodulin as a mediator of hormone action and cell regulation
Lisette Lagace
Journal of Cellular Biochemistry, 1982
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Insulin stimulates the phosphorylation of calmodulin in intact adipocytes
Jerry Colca
Journal of Biological Chemistry
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Ca2+/calmodulin-dependent protein kinase II δ2 regulates gene expression of insulin in INS-1 rat insulinoma cells
Martin Osterhoff
Cell Calcium, 2003
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Alloxan inhibition of a Ca2+- and calmodulin-dependent protein kinase activity in pancreatic islets
Jerry Colca
Journal of Biological Chemistry
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Regulation of pancreatic islet-cell plasma membrane Ca2+ + Mg2+-ATPase by Calmodulin
Jerry Colca
FEBS Letters, 1982
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Functional in vitro test of calmodulin antagonism: effect of drugs on interaction between calmodulin and glycolytic enzymes
Ferenc Orosz
Molecular pharmacology, 1988
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Potassium Channels, Imidazolines, and Insulin-Secreting Cells
Paul Squires
Annals of the New York Academy of Sciences, 1995
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PHARMACOLOGICAL REGULATION OF CALMODULIN*
Benjamin Weiss
Annals of the New …, 1980
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Effect of calmidazolium on Ca2+ movement and proliferation in human osteosarcoma cells
Bang-Ping Jiann
Clinical and Experimental Pharmacology and Physiology, 2004
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Depolarizing Stimuli Reduce Ca2+/Calmodulin-Dependent Protein Kinase II Activity in Islets of Langerhans
Paul Squires
Biochemical and Biophysical Research Communications, 2000
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The Imidazoline RX871024 Stimulates Insulin Secretion in Pancreatic β-Cells from Mice Deficient in KATP Channel Function
Mark A Magnuson
Biochemical and Biophysical Research Communications, 2001
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Phospholipid-sensitive Ca2+-dependent protein kinase inhibition by R-24571, a calmodulin antagonist
Raymond S Turner
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Phosphorylation of calmodulin. Functional implications
Gustavo Benaim
European Journal of Biochemistry
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Calmodulin and its role in intracellular calcium regulation
J.-c. Stoclet
Progress in Neurobiology, 1987
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Phosphorylation of calmodulin
Gustavo Benaim
European Journal of Biochemistry, 2002
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Calmodulin in endocrine cells and its multiple roles in hormone action
Anthony Means
Molecular and Cellular Endocrinology, 1980
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Ca2+-Calmodulin-dependent Facilitation and Ca2+ Inactivation of Ca2+ Release-activated Ca2+ Channels
Sebastian Straube
Journal of Biological Chemistry, 2005
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Calcium-dependent binding of calmodulin to phospholipase A2 subunits induces enzymatic activation
Walter Silva
Archives of Biochemistry and Biophysics, 1985
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Calmodulin content and in vitro contractility of duodenum from streptozotocin-induced diabetic rats: effects of insulin therapy and calmodulin antagonism
Yusuf Öztürk
European Journal of Pharmacology, 1997
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