Total Synthesis Research Papers - Academia.edu (original) (raw)

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- Organic Chemistry, Total Synthesis
- by Roger Newton
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- Total Synthesis
- by Hiroaki Sasai
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- Organic Chemistry, Total Synthesis

We wish to report here our initial efforts toward the total synthesis of the potent antitumor agent dictyostatin, describing a short and efficient synthesis of the C11–C23 fragment. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim,... more

- by Caroline Gonçalves
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- Organic Chemistry, European, Total Synthesis, Chemical Synthesis
- by Madeleine M. Joullie
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- Organic Chemistry, Total Synthesis
- by Rachel Kely
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- Organic Chemistry, Kinetics, Enzyme Inhibitors, Humans
- by Elaine Pereira
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- Organic Chemistry, Titanium, Total Synthesis
- by Geo Adam
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- Macrocycle, CHEMICAL SCIENCES, Total Synthesis, Absolute Configuration
- by Kosuke Yasuda
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- Tacrolimus, CHEMICAL SCIENCES, Total Synthesis, Oxidation
- by Piotr Balczewski
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- Organic Chemistry, Total Synthesis, Tetrahedron
- by Alexandre Bouillon
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- Inorganic Chemistry, Organic Chemistry, Suzuki Miyaura cross-coupling, The
- by Van Quy Pham
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- Organic Chemistry, Mass Spectrometry, Pharmacognosy, Cytotoxicity
- by Sudipto Das
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- Multidisciplinary, Escherichia coli, Calcium channels, Natural Product
- by Kyoko Nakagawa-goto
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- Organic Chemistry, Total Synthesis
- by Margaret Chu-Moyer
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- CHEMICAL SCIENCES, Total Synthesis

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

- by Jaya Surya
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- Organic Chemistry, Total Synthesis
- by Nicos A Petasis
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- CHEMICAL SCIENCES, Total Synthesis, The American
- by Paul Grieco
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- CHEMICAL SCIENCES, Total Synthesis
- by James M Hook
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- CHEMICAL SCIENCES, Total Synthesis, The American
- by Jack Frazee
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- The, CHEMICAL SCIENCES, Total Synthesis
- by Biswajit Samanta
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- Organic Chemistry, Photochemistry, Total Synthesis, Oxidation
- by Marcela Valenzuela
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- Inorganic Chemistry, Organic Chemistry, Catalysis, Medicinal Plants
- by Pablo Bernal
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- CHEMICAL SCIENCES, Total Synthesis
- by Chewki Ziani Cherif
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- Inorganic Chemistry, Organic Chemistry, Total Synthesis

ABSTRACT (−) and (+) α-Allokainoids hydrochlorides 3 and 4 were obtained by hydrolysis of the corresponding Michael adducts resulting from the addition of diethyl malonate to chiral N-urethane protected ethyl... more

- by Almudena Rubio
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- Total Synthesis
- by Milan Potáček
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- Organic Chemistry, Total Synthesis
- by S. Hazen
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- Inorganic Chemistry, Organic Chemistry, Phospholipids, Macular Degeneration
- by Michael Lilly
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- Organic, CHEMICAL SCIENCES, Total Synthesis, Epidermal Growth Factor

For Abstract see ChemInform Abstract in Full Text.

- by jagat C borah
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- Organic Chemistry, Total Synthesis, Nitrosation

An asymmetric synthesis of 12-membered ring macrolide, chloriolide has been accomplished by adopting a linear strategy. Lipase-catalyzed enzymatic kinetic resolution (EKR), asymmetric alkynylation using Trost pro-phenol catalyst followed... more

- by Nandan Jana
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- Organic Chemistry, Kinetics, Asymmetric Synthesis, Total Synthesis
- by Georgios Vassilikogiannakis
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- Organic Chemistry, Catalysis, Molecular Diversity, Nobel Prize
- by Michael Crimmins
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- The, CHEMICAL SCIENCES, Total Synthesis

The chemistry of salt is of great importance due to its immense potential from the daily life use to the synthetic chemistry like as workup material, as reagents, as phase transfer catalyst, as acid, as base, as catalyst, as agents for asymmetric synthesis, for some specific reaction transformation, to increase yield, decrease reaction time, ecofriendly synthesis, handling easiness and many more. This review summarizes the overall basic background of salts like how it is formed, nature of salt, generalized application of salts in daily life to synthetic chemistry, its application on other diverse fields, and list of individual categories of major commercially available salts with some structure. Besides having a lot of information on the internet about salts, this review tries to focus on a generalized overview that could be helpful for all to understand salt chemistry.

- by Dirgha Raj Joshi
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- Organic Chemistry, Synthetic Organic Chemistry, Organic Synthesis, Organic Acids
- by Daniel Romo
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- Organic Chemistry, Natural Product, Total Synthesis, Heterocycles
- by jagat C borah
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- Organic Chemistry, Total Synthesis, Nitrosation
- by Majid Heravi
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- Palladium, Total Synthesis, Tetrahedron

Abstract Salvinorin A is a neoclerodane diterpene that has been shown to be an agonist at kappa opioid receptors. Its unique structure makes it an attractive target for synthetic organic chemists due to its seven chiral centers and diterpene scaffold. This molecule is also interesting to pharmacologists because it is a non-serotonergic hallucinogen, and the first opioid ligand discovered that lacks a basic nitrogen. There have been several total synthesis approaches to salvinorin A, and these will be detailed within this chapter. Additionally, research efforts have concentrated on structure modification of the salvinorin A scaffold through semi-synthetic methods. Most modifications have focused on the manipulation of the acetate at C-2 and the furan ring. However, chemistry has also been developed to generate analogs at the C-1 ketone, the C-4 methyl ester, and the C-17 lactone. The synthetic methodologies developed for the salvinorin A scaffold will be described, as well as specific analogs with interesting biological activities. Graphical Abstract

- by Anthony Lozama
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- Humans, Animals, Nitrogen, CHEMICAL SCIENCES
- by Patrick Perlmutter
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- Organic Chemistry, Total Synthesis, Tetrahedron
- by michael edwards
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- Organic Chemistry, Total Synthesis, Tetrahedron, Stille Coupling
- by David González
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- Inorganic Chemistry, Organic Chemistry, Catalysis, Medicinal Plants
- by Julie Warne
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- Chemistry, Organic Chemistry, Alcohol, Total Synthesis
- by vikas kumar
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- Total Synthesis
- by Daniel Salvatierra Romo
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- Organic Chemistry, Natural Product, Total Synthesis, Heterocycles
- by Lalith Perera
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- Chemistry, Macromolecular X-Ray Crystallography, Humans, CHEMICAL SCIENCES
- by Michael Crimmins
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- The, CHEMICAL SCIENCES, Total Synthesis