Rajesh H | Yenepoya - Academia.edu (original) (raw)

Papers by Rajesh H

Context: In developing countries many chronic conditions including periodontitis are on the rise.... more Context: In developing countries many chronic conditions including periodontitis are on the rise. Oral health
attitudes and beliefs are important factors affecting oral health behavior. Aims: The aim of this pilot study was to
assess the existing knowledge about periodontal disease and its impact on treatment seeking behavior in a group
of population visiting the out‑patient Department of Periodontics, Yenepoya Dental College, India. This study also
attempted to identify deficit in the knowledge if present. Settings and Design: This is a written questionnaire
based pilot study. 143 subjects (89 male and 54 female) agreed to participate in the study. Simple random
sampling was used for recruitment. Subjects and Methods: A written questionnaire consisting of 18 questions
was given to the patients. Only one correct answer was present and the score given was + 1. The knowledge
of the subjects was reflected by their ability to select a correct answer from the number of distractors (multiple
choices, prespecified answers). Statistical Analysis Used: SPSS software version 15.0 is used for all statistical
analysis. The Chi‑square test was employed to assess the passive knowledge of the participants in relation to
their age. Results: We found a deficit in the knowledge in all the topics investigated. No consistent relationship
between age and gender was found. Female respondents had better knowledge about oral hygiene compared
to males. Conclusion: We made an attempt to assess the knowledge of periodontitis among the participants
of this study. Knowledge deficit was found in the population surveyed. This knowledge deficit could be one of
the reasons why patients do not seek periodontal treatment routinely unless there are acute symptoms. There
is urgent need to educate the patients about the periodontal disease, the need for the treatment of periodontitis
and advanced treatment modalities available.

Root resection procedures are indicated in the treatment of advanced Grade II and Grade III furca... more Root resection procedures are indicated in the treatment of advanced Grade II and Grade III furcation involvement. Their long-term
prognosis is comparable to that of implants. The objective of this article is to present case reports of hemisection in mandibular first
molar and root amputation in maxillary second molar, employed successfully as a part of the oral rehabilitation procedure.

Context: Local drug delivery (LDD) systems have been proposed for the treatment of periodontitis... more Context: Local drug delivery (LDD) systems have been proposed for the treatment of
periodontitis. Curcumin could be a suitable agent as LDD for the treatment of periodontitis.
Aim: To formulate, evaluate the anti-inflammatory activity and to assess the duration
of the action and the efficacy of 2% curcumin gel in the treatment of experimental
periodontitis in Wistar albino rat model. Settings and Design: Twenty-one Wistar albino
rats were randomly assigned to three groups. Periodontitis was induced using ligature
model. Group 1: Control; group 2: Plain gel, and group 3: 2% curcumin gel. Materials
and Methods: About 2% curcumin gel was prepared. The anti-inflammatory activity
and duration of action was assessed. Silk ligature 5-0 was used to induce periodontitis.
Gingival index (GI) and probing pocket depth (PPD) were measured. Treatment was done.
The rats were sacrificed. Morphometric analysis was performed using stereomicroscope
and ImageJ software. Statistical Analysis Used: Analysis of variance followed by
Bonferroni’s test, Wilcoxon’s test for inter-group comparison, Mann–Whitney test for
P value computation was used. The observations are mean ± standard deviation and
standard error of the mean. P < 0.01 when compared to control was considered as
statistically significant. Results: About 2% curcumin gel showed 42.98% inhibition of
edema and peak activity was noted at 24 h. There was statistically significant change in
the GI and PPD. Morphometric analysis did not show any significant difference between
groups. No toxic effects were seen on oral administration of 2000 mg/kg of curcumin.
Conclusions: About 2% curcumin gel was effective in the treatment of experimental periodontitis.

Ocimum sanctum Linn also known as Tulsi or Holybasil is an aromatic plant. It belongs to the fami... more Ocimum sanctum Linn also known as Tulsi or Holybasil is an aromatic plant. It belongs to the family Lamiaceae. It is widely used in Ayurveda and Siddha system of medicine to cure various ailments.

Medicinal plants are a rich source of numerous pharmacologically active molecules. Scientists are... more Medicinal plants are a rich source of numerous pharmacologically active molecules. Scientists are currently focusing on the Phytochemicals to treat numerous ailments affecting the mankind. Curcuma longa (Turmeric) a rhizomatous perennial plant belonging to family Zingiberaceae is widely used as a food additive and as traditional medicine for treating various ailments. It has anti-inflammatory, antifungal, antimicrobial, virucidal, anti mutagenic and antioxidant properties. In view of this phytochemical analysis of Methanolic extract was done. The purpose of the study was to do preliminary phytochemical screening of the Methanolic extract of the turmeric rhizome. 40g of powdered turmeric rhizome was extracted with methanol in the Soxhlet extractor for 36 hours. The extract was concentrated using Rotavapor and dried. The residue yielded a reddish brown sticky mass. The yield was 9% w/w. The preliminary phytochemical analysis of the Methanolic extract showed the presence of tannins, alkaloids, saponins, flavonoids, terpenoids and cardiac glycosides.

An assessment of whether to rehabilitate a tooth requiring endodontic treatment or to replace it ... more An assessment of whether to rehabilitate a tooth requiring endodontic treatment or to replace it with a dental implant can often involve a challenging and complex decision making process. This paper discusses the literature pertaining to both treatment modalities and identifies key issues that need careful consideration in planning the most appropriate course of care in a given clinical situation. A need to appreciate advances across both disciplines is highlighted, allowing the development of effective interdisciplinary evidence-based treatment strategies to maximize treatment outcome.

Context: Clinical evaluation of gingivitis and/or periodontitis does not predict the progression ... more Context: Clinical evaluation of gingivitis and/or periodontitis does not predict the progression or remission of the disease. Due to this diagnostic constraint, clinicians assume that the pathology has an increased risk of progression and plan treatments, despite the knowledge that all inflamed sites are not necessarily progressing. Extensive research has been carried out on gingival crevicular fluid (GCF) components that might serve as potential diagnostic markers for periodontitis. Among them alkaline phosphatase (ALP) levels in GCF has shown promise as a diagnostic marker. Aim: This study compares the levels of GCF alkaline phosphatase in patients with chronic periodontitis before and after scaling and root planing. Materials and Methods: This study is an in vivo longitudinal study conducted on twenty patients with localized periodontitis. The GCF was collected from the affected site prior to scaling and root planing and ALP level estimated. The probing depth and plaque index at the site were also measured for correlation. Patients were recalled after 7, 30, and 60 days for reassessment. Results: The GCF ALP values showed a sustained, statistically significant decrease after treatment. There was a positive correlation with probing depth but not with plaque index measured at each interval. Conclusion: The assessment of level of periodontal disease and effect of mechanical plaque control on the progression and regression of the disease can be evaluated precisely by the corresponding GCF ALP levels. Thus, alkaline phosphatase level is not only a biomarker for the pathology but also an indicator of prognosis of periodontitis.

Aim : Bioactive glass composite (HABG) is a novel material. The aim of this study was to assess t... more Aim : Bioactive glass composite (HABG) is a novel material. The aim of this study was to assess the efficacy and compare Hydroxyapatite Bioactive glass composite (HABG) and synthetic resorbable hydroxyapatite OsteoGen (HA RESORB) ® in human volunteers over a span of 9 months. Methods: It was a double blind randomized case-control study involving 16 volunteers with infra bony defects. OsteoGen (HA ® resorb) was control and Chithra HABG composite was the test material. The clinical parameters and bone level were noted preoperatively and 9 months in both groups. Results: SPSS 10 Version 10.0 software programme was used. On comparison between 2 groups no statistically significant difference was seen (P>0.05). Conclusion: Test and control material showed improvement in clinical parameters and bone fill was seen in both the groups ® which were comparable. HABG composite is equally efficient alloplast when compared to OsteoGen (HA resorb) .