| dbo:abstract |
سيفيلامير (بالإنجليزية: Sevelamer) عقار تركيبه الكيماوي سيفيلامير هيدروكلورايد، دواء رابط للفوسفات. يستخدم لخفض تركيز فوسفور المصل عند المريض المصاب بالداء الكلوي بمراحله النهائية. (ar) Sevelamer (rINN) ist ein Arzneistoff aus der Gruppe der Phosphatbinder, der bei Dialysepatienten mit Phosphatüberschuss im Blut (Hyperphosphatämie) zur Bindung des Phosphats aus der Nahrung eingesetzt wird. Sevelamer kommt in zwei verschiedenen Salzformen zur Anwendung, dem Sevelamerhydrochlorid und dem Sevelamercarbonat. (de) El Sevelamer (DCI) (AFI: [sɛˈvɛləmə, -mər, -mir]) es un fármaco quelante de fosfato usado para prevenir la hiperfosfatemia en pacientes con insuficiencia renal crónica. Cuando es tomado con las comidas, el sevelamer se enlaza al fosfato de la dieta y previene su absorción. Es mercadeado por Genzyme bajo el nombre comercial de Renagel®. (es) Sevelamer (rINN) is a phosphate binding medication used to treat hyperphosphatemia in patients with chronic kidney disease. When taken with meals, it binds to dietary phosphate and prevents its absorption. Sevelamer was invented and developed by GelTex Pharmaceuticals. Sevelamer is marketed by Sanofi under the brand names Renagel (sevelamer hydrochloride) and Renvela (sevelamer carbonate). (en) 세벨라머(rINN: Sevelamer, /sɛˈvɛləmər/ or /sɛˈvɛləmɪər/)는 투석을 받고 있는 만성콩팥병 환자에서 고인산혈증이 발생하였을 때 혈중 인 수치를 낮추기 위해 사용되는 이다. (ko) |
| dbo:alternativeName |
Renagel, Renvela (en) |
| dbo:bioavailability |
0.000000 (xsd:float) |
| dbo:casNumber |
52757-95-6 |
| dbo:chEMBL |
1201492 |
| dbo:chemicalFormula |
[(C3H7N)a+b.(C9H17N2O)c]m where a+b:c = 9:1 |
| dbo:drugbank |
DB00658 |
| dbo:fdaUniiCode |
941N5DUU5C |
| dbo:kegg |
D01983 D08512 |
| dbo:medlinePlus |
a601248 |
| dbo:pubchem |
3085017 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Sevelamer.png?width=300 |
| dbo:wikiPageExternalLink |
https://druginfo.nlm.nih.gov/drugportal/name/sevelamer%20carbonate https://druginfo.nlm.nih.gov/drugportal/name/sevelamer%20hydrochloride https://druginfo.nlm.nih.gov/drugportal/rn/52757-95-6 |
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2589351 (xsd:integer) |
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8052 (xsd:nonNegativeInteger) |
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| dbo:wikiPageWikiLink |
dbr:Calcium_acetate dbr:Calcium_carbonate dbr:Carbonate dbr:Proton dbr:Sanofi dbc:Nephrology_procedures dbr:Hydrogen_bond dbr:Beta_cell dbr:Uric_acid dbr:Gas dbr:Low-density_lipoprotein dbr:Nausea dbr:Oral_administration dbr:Epichlorohydrin dbr:Gout dbr:Constipation dbr:Feces dbr:Acute-phase_protein dbr:Amine dbc:Phosphate_binders dbr:Pancreas dbr:Chronic_kidney_disease dbr:Diarrhea dbr:Vomiting dbr:Heartburn dbr:International_Nonproprietary_Name dbr:Hydrochloride dbr:Hyperphosphatemia dbr:Hypophosphatemia dbr:Polyallylamine_hydrochloride dbr:Abdominal_pain dbr:Adverse_drug_reaction dbc:Sanofi dbr:Cholesterol dbr:Insulin dbr:Phosphate_binder dbr:Ionic_bond dbr:Oxidative_stress dbr:Hyperphosphataemia dbr:Hypercalcemia |
| dbp:atcPrefix |
V03 (en) |
| dbp:atcSuffix |
AE02 (en) |
| dbp:bioavailability |
0.0 (dbd:perCent) |
| dbp:casNumber |
52757 (xsd:integer) |
| dbp:chembl |
1201492 (xsd:integer) |
| dbp:chemicalFormula |
[a+b.c]m (en) where a+b:c = 9:1 (en) |
| dbp:chemspiderid |
2341997 (xsd:integer) |
| dbp:dailymedid |
Sevelamer (en) |
| dbp:drugbank |
DB00658 (en) |
| dbp:excretion |
Feces 100% (en) |
| dbp:index2Label |
as HCl (en) |
| dbp:iupacName |
poly (en) |
| dbp:kegg |
D01983 (en) D08512 (en) |
| dbp:legalAu |
S4 (en) |
| dbp:legalEu |
Rx only (en) |
| dbp:legalUs |
Rx only (en) |
| dbp:licenceEu |
yes (en) |
| dbp:medlineplus |
a601248 (en) |
| dbp:molecularWeight |
variable (en) |
| dbp:pregnancyAu |
B3 (en) |
| dbp:pregnancyUs |
C (en) |
| dbp:pronounce |
(en) |
| dbp:pubchem |
3085017 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Oral_administration |
| dbp:tradename |
Renagel, Renvela (en) |
| dbp:unii |
941 (xsd:integer) |
| dbp:verifiedfields |
changed (en) |
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408746510 (xsd:integer) |
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dbt:Cite_web dbt:Cn dbt:Drugbox dbt:IPAc-en dbt:Portal_bar dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Drugs.com dbt:Drugs_for_treatment_of_hyperkalemia_and_hyperphosphatemia |
| dct:subject |
dbc:Nephrology_procedures dbc:Phosphate_binders dbc:Sanofi |
| gold:hypernym |
dbr:Drug |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Artifact100021939 yago:Binder102840361 yago:Device103183080 yago:FarmMachine103322940 yago:Harvester103496892 yago:Instrumentality103575240 yago:Machine103699975 yago:Object100002684 yago:PhysicalEntity100001930 dbo:Drug yago:Whole100003553 yago:WikicatPhosphateBinders |
| rdfs:comment |
سيفيلامير (بالإنجليزية: Sevelamer) عقار تركيبه الكيماوي سيفيلامير هيدروكلورايد، دواء رابط للفوسفات. يستخدم لخفض تركيز فوسفور المصل عند المريض المصاب بالداء الكلوي بمراحله النهائية. (ar) Sevelamer (rINN) ist ein Arzneistoff aus der Gruppe der Phosphatbinder, der bei Dialysepatienten mit Phosphatüberschuss im Blut (Hyperphosphatämie) zur Bindung des Phosphats aus der Nahrung eingesetzt wird. Sevelamer kommt in zwei verschiedenen Salzformen zur Anwendung, dem Sevelamerhydrochlorid und dem Sevelamercarbonat. (de) El Sevelamer (DCI) (AFI: [sɛˈvɛləmə, -mər, -mir]) es un fármaco quelante de fosfato usado para prevenir la hiperfosfatemia en pacientes con insuficiencia renal crónica. Cuando es tomado con las comidas, el sevelamer se enlaza al fosfato de la dieta y previene su absorción. Es mercadeado por Genzyme bajo el nombre comercial de Renagel®. (es) Sevelamer (rINN) is a phosphate binding medication used to treat hyperphosphatemia in patients with chronic kidney disease. When taken with meals, it binds to dietary phosphate and prevents its absorption. Sevelamer was invented and developed by GelTex Pharmaceuticals. Sevelamer is marketed by Sanofi under the brand names Renagel (sevelamer hydrochloride) and Renvela (sevelamer carbonate). (en) 세벨라머(rINN: Sevelamer, /sɛˈvɛləmər/ or /sɛˈvɛləmɪər/)는 투석을 받고 있는 만성콩팥병 환자에서 고인산혈증이 발생하였을 때 혈중 인 수치를 낮추기 위해 사용되는 이다. (ko) |
| rdfs:label |
سيفيلامير (ar) Sevelamer (de) Sevelamer (es) 세벨라머 (ko) Sevelamer (en) |
| owl:sameAs |
freebase:Sevelamer http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB00658 yago-res:Sevelamer http://www4.wiwiss.fu-berlin.de/sider/resource/drugs/3085017 wikidata:Sevelamer dbpedia-ar:Sevelamer dbpedia-cy:Sevelamer dbpedia-de:Sevelamer dbpedia-es:Sevelamer dbpedia-ko:Sevelamer dbpedia-sh:Sevelamer dbpedia-sl:Sevelamer dbpedia-sr:Sevelamer dbpedia-tr:Sevelamer dbpedia-vi:Sevelamer https://global.dbpedia.org/id/54M6s |
| prov:wasDerivedFrom |
wikipedia-en:Sevelamer?oldid=1078526920&ns=0 |
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wiki-commons:Special:FilePath/Sevelamer.png |
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wikipedia-en:Sevelamer |
| is dbo:wikiPageRedirects of |
dbr:ATC_code_V03AE02 dbr:ATCvet_code_QV03AE02 dbr:Renagel dbr:Renvela dbr:Sevelamer_Hydrochloride dbr:Sevelamer_carbonate dbr:Sevelamer_hydrochloride |
| is dbo:wikiPageWikiLink of |
dbr:Calcium_carbonate dbr:Sanofi dbr:Uric_acid dbr:List_of_largest_selling_pharmaceutical_products dbr:Ciprofloxacin dbr:Levothyroxine dbr:Sucroferric_oxyhydroxide dbr:Panacea_Biotec dbr:ATC_code_V03AE02 dbr:ATCvet_code_QV03AE02 dbr:Hyperphosphatemia dbr:Hyperuricemia dbr:Hypouricemia dbr:ATC_code_V03 dbr:Phosphate_binder dbr:Renal_osteodystrophy dbr:List_of_drugs:_Se–Sh dbr:Renagel dbr:Renvela dbr:Sevelamer_Hydrochloride dbr:Sevelamer_carbonate dbr:Sevelamer_hydrochloride |
| is foaf:primaryTopic of |
wikipedia-en:Sevelamer |
