Atractyloside (original) (raw)
Atractylosid (ATR) ist ein natürliches, giftiges Glycosid und ein effektiver Inhibitor des ATP/ADP-Translokators.
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|---|---|
| dbo:abstract | Atractylosid (ATR) ist ein natürliches, giftiges Glycosid und ein effektiver Inhibitor des ATP/ADP-Translokators. (de) Atractyloside (ATR) is a natural, toxic glycoside present in numerous plant species worldwide in the daisy family including Atractylis gummifera and , and it's used for a variety of therapeutic, religious, and toxic purposes. Exposure to ATR via ingestion or physical contact is toxic and can be fatal for both humans and animals, especially by kidney and liver failure. ATR acts as an effective ADP/ATP translocase inhibitor which eventually halts ADP and ATP exchange and the cell dies due to lack of energy. Historically, atractyloside poisoning has been challenging to verify and quantify toxicologically, though recent literature has described such methods within acceptable standards of forensic science. (en) L'atractyloside est un composé organique de formule C30H46O16S2. C'est un glycoside diterpénoïde naturel, toxique, et un inhibiteur efficace de la translocase ATP/ADP. Ce composé est synthétisé par certaines espèces de plantes de la famille des Asteraceae, par exemple , Carlina gummifera, Xanthium strumarium, et . (fr) Атрактилозид — органическое вещество, гликозид. Обладает высокой токсичностью за счет ингибирования транслоказы — белка, расположенного в мембране митохондрий и ответственного за обменную диффузию АДФ и АТФ. (ru) |
| dbo:alternativeName | ATR (en) Atractylate (en) Atractylic Acid (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Atractyloside_skeletal.svg?width=300 |
| dbo:wikiPageID | 53878539 (xsd:integer) |
| dbo:wikiPageLength | 19989 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1105283933 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Calibration_curve dbr:Carboxyatractyloside dbr:Electrospray_ionization dbr:Mole_(unit) dbr:NMR dbc:Poisons dbr:Decoction dbr:Infusion dbr:Inner_mitochondrial_membrane dbr:Intravenous_therapy dbr:Lethal_dose dbc:Alkene_derivatives dbc:Carboxylate_esters dbc:Carboxylic_acids dbc:Diols dbc:Sulfate_esters dbr:Coma dbr:Competitive_inhibition dbr:Glucose dbr:Mitochondria dbr:Subcutaneous_injection dbr:Zulu_people dbr:Daisy_family dbr:Tandem_mass_spectrometry dbr:Acute_liver_failure dbr:Diterpene dbr:Liquid_chromatography–mass_spectrometry dbr:Acute_tubular_necrosis dbr:Adenosine_diphosphate dbr:Adenosine_triphosphate dbr:Glycoside dbr:Glycosidic_bond dbr:Kidney_failure dbr:Hepatorenal_syndrome dbr:High-performance_liquid_chromatography dbc:ADP/ATP_translocase_inhibitors dbc:Diterpene_glycosides dbr:Intraperitoneal_injection dbr:Hydrolysis dbr:Hypoventilation dbr:ADP/ATP_translocase dbr:Abdominal_pain dbc:Plant_toxins dbr:Sulfate dbr:Sulfuric_acid dbr:Coffea_arabica dbr:Non-competitive_inhibition dbr:Xanthium_strumarium dbr:Isovaleric_acid dbr:Hydroxyl_group dbr:Atractylis_gummifera dbr:Mmol dbr:Carboxyl_group dbr:Deprotonated dbr:Callilepis_laureola dbr:File:ATR-CATR_Numbered_Diagram.png dbr:File:Atractyligenin_Numbered_Diagram.png dbr:File:Atractylis_gummifera.jpg dbr:Iphiona_alsoeri dbr:Iphiona_aucheri dbr:Pascalia_glauca dbr:Wedelia_glauca |
| dbp:imagecaption | Structure formula of atractyloside (en) |
| dbp:imagefile | Atractyloside skeletal.svg (en) |
| dbp:imagesize | 250 (xsd:integer) |
| dbp:name | Atractyloside (en) |
| dbp:othernames | (en) ATR (en) Atractylate (en) Atractylic Acid (en) |
| dbp:wikiPageUsesTemplate | dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Cascite dbt:Chembox_Structure dbt:Fdacite |
| dct:subject | dbc:Poisons dbc:Alkene_derivatives dbc:Carboxylate_esters dbc:Carboxylic_acids dbc:Diols dbc:Sulfate_esters dbc:ADP/ATP_translocase_inhibitors dbc:Diterpene_glycosides dbc:Plant_toxins |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound |
| rdfs:comment | Atractylosid (ATR) ist ein natürliches, giftiges Glycosid und ein effektiver Inhibitor des ATP/ADP-Translokators. (de) Atractyloside (ATR) is a natural, toxic glycoside present in numerous plant species worldwide in the daisy family including Atractylis gummifera and , and it's used for a variety of therapeutic, religious, and toxic purposes. Exposure to ATR via ingestion or physical contact is toxic and can be fatal for both humans and animals, especially by kidney and liver failure. ATR acts as an effective ADP/ATP translocase inhibitor which eventually halts ADP and ATP exchange and the cell dies due to lack of energy. Historically, atractyloside poisoning has been challenging to verify and quantify toxicologically, though recent literature has described such methods within acceptable standards of forensic science. (en) L'atractyloside est un composé organique de formule C30H46O16S2. C'est un glycoside diterpénoïde naturel, toxique, et un inhibiteur efficace de la translocase ATP/ADP. Ce composé est synthétisé par certaines espèces de plantes de la famille des Asteraceae, par exemple , Carlina gummifera, Xanthium strumarium, et . (fr) Атрактилозид — органическое вещество, гликозид. Обладает высокой токсичностью за счет ингибирования транслоказы — белка, расположенного в мембране митохондрий и ответственного за обменную диффузию АДФ и АТФ. (ru) |
| rdfs:label | Atractyloside (en) Atractylosid (de) Atractyloside (fr) Атрактилозид (ru) |
| owl:sameAs | yago-res:Atractyloside wikidata:Atractyloside dbpedia-de:Atractyloside dbpedia-fr:Atractyloside dbpedia-ru:Atractyloside https://global.dbpedia.org/id/4pXfs |
| prov:wasDerivedFrom | wikipedia-en:Atractyloside?oldid=1105283933&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Atractylis_gummifera.jpg wiki-commons:Special:FilePath/ATR-CATR_Numbered_Diagram.png wiki-commons:Special:FilePath/Atractyligenin_Numbered_Diagram.png wiki-commons:Special:FilePath/Atractyloside_skeletal.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Atractyloside |
| foaf:name | Atractyloside (en) |
| is dbo:wikiPageDisambiguates of | dbr:ATR |
| is dbo:wikiPageRedirects of | dbr:C30H46O16S2 |
| is dbo:wikiPageWikiLink of | dbr:Carboxyatractyloside dbr:List_of_MeSH_codes_(D02) dbr:C30H46O16S2 dbr:Adenine_nucleotide_translocator dbr:List_of_MeSH_codes_(D09) dbr:ATR dbr:Chamaeleon_gummifer |
| is foaf:primaryTopic of | wikipedia-en:Atractyloside |
