| dbo:abstract |
Blueberry muffin baby, also known as extramedullary hematopoiesis, describes a newborn baby with multiple purpura, associated with several non-cancerous and cancerous conditions in which extra blood is produced in the skin. The bumps range from 1-7mm, do not blanche and have a tendency to occur on the head, neck and trunk. They often fade by 3 to 6 weeks after birth, leaving brownish marks. When due to a cancer, the bumps tend to be fewer, firmer and larger. It can occur following infection of an unborn baby with rubella, cytomegalovirus, toxoplasmosis, or coxsackie virus. Other viral causes include parvovirus B19 and herpes simplex. Non-infectious causes include haemolytic disease of the newborn, hereditary spherocytosis, twin-to-twin transfusion syndrome and recombinant erythropoietin administration. Some types of cancers can cause it such as rhabdomyosarcoma, extrosseal Ewing sarcoma, Langerhans cell histiocytosis, congenital leukaemia and neuroblastoma. During normal development of an unborn baby, blood production can occur in the skin until the fifth month of pregnancy. Blueberry muffin lesions in the newborn indicate the prolongation of skin blood production after birth. Diagnosis involves a combination of appearance and laboratory studies, including blood tests for complete blood count, TORCH infections, haemoglobin, viral cultures and Coombs test. A skin biopsy may be useful. Conditions that may appear similar include hemangiopericytoma, blue rubber bleb nevus, hemangioma and glomangioma. Prognosis is variable based upon the cause of the characteristic rash. Treatment may include supportive care, anti-viral medication, transfusion, or chemotherapy depending on the underlying cause. It is not common. The term was coined in the 1960s to describe the skin changes in babies with congenital rubella. Since then, it has been realised that blueberry muffin marks occur in several conditions. (en) |
| dbo:differentialDiagnosis |
dbr:Hemangioma dbr:Glomangioma dbr:Hemangiopericytoma dbr:Blue_rubber_bleb_nevus |
| dbo:medicalCause |
dbr:Congenital_rubella |
| dbo:medicalDiagnosis |
dbr:Complete_blood_count dbr:Haemoglobin dbr:TORCH_infection |
| dbo:medicalSpecialty |
dbr:Dermatology dbr:Pediatrics |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Blueberry_muffin_baby.jpg?width=300 |
| dbo:wikiPageID |
21711550 (xsd:integer) |
| dbo:wikiPageLength |
15036 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1116115126 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Cataracts dbr:Rubella dbr:Parvovirus_B19 dbr:Biopsy dbr:Blood_transfusion dbr:Hydrocephalus dbr:Rhabdomyosarcoma dbr:Cytomegalovirus dbr:Valganciclovir dbr:Dermatology dbr:Polymerase_chain_reaction dbr:Complete_blood_count dbr:Meningitis dbr:Ganciclovir dbr:Anemia dbr:Leukaemia dbr:Leukemia dbr:Lupus dbr:Lymphoma dbr:MMR_vaccine dbr:Chorioretinitis dbr:Hemangioma dbr:Hemolytic_disease_of_the_newborn dbr:Pediatrics dbr:Autosomal_dominant dbr:Glaucoma dbr:Langerhans_cell dbr:Toxoplasmosis dbr:Acute_myeloid_leukemia dbr:Erythropoietin dbr:Ewing_sarcoma dbr:Glomangioma dbr:Haemoglobin dbr:Purpura dbr:Hemangiopericytoma dbr:Hepatosplenomegaly dbr:Herpes_simplex dbr:Jaundice dbr:Hutchinson's_teeth dbc:Vascular-related_cutaneous_conditions dbr:Adrenal_gland dbr:Chemotherapy dbr:Langerhans_cell_histiocytosis dbr:Syphilis dbr:Hepatomegaly dbr:Hereditary_spherocytosis dbr:Herpesviridae dbr:Splenomegaly dbr:Papules dbr:Microcephaly dbr:Neonate dbr:Neuroblastoma dbr:Seizures dbr:White_blood_cell dbr:Neuroblast dbr:Extramedullary_hematopoiesis dbr:Immunohistochemistry dbr:Lymphadenopathy dbr:Saber_shin dbr:Sensorineural_hearing_loss dbr:Twin-to-twin_transfusion_syndrome dbr:Treponema_pallidum dbr:Thrombocytopenia dbr:List_of_cutaneous_conditions dbr:Haemolytic_disease_of_the_newborn dbr:Epstein_Barr_virus dbr:Macules dbr:Coxsackie_virus dbr:Blue_rubber_bleb_nevus dbr:Congenital_rubella dbr:Hematopoiesis dbr:TORCH_infection |
| dbp:caption |
A newborn baby with typical lesions of a blueberry muffin baby. (en) |
| dbp:causes |
Congenital rubella, congenital CMV, other TORCH infections, blood disorders, and malignancies (en) |
| dbp:diagnosis |
Blood tests for complete blood count, TORCH infections, haemoglobin, viral cultures and Coombs test, skin biopsy (en) |
| dbp:differential |
dbr:Hemangioma dbr:Glomangioma dbr:Hemangiopericytoma dbr:Blue_rubber_bleb_nevus |
| dbp:frequency |
Uncommon (en) |
| dbp:prevention |
MMR vaccine covers for congenital rubella (en) |
| dbp:specialty |
dbr:Dermatology dbr:Pediatrics |
| dbp:symptoms |
Reddish-blue purpura localized mainly to the face, neck, and trunk (en) |
| dbp:wikiPageUsesTemplate |
dbt:Citation_needed dbt:Infobox_medical_condition_(new) dbt:Reflist dbt:DermAtlas |
| dcterms:subject |
dbc:Vascular-related_cutaneous_conditions |
| gold:hypernym |
dbr:Purpura |
| rdf:type |
owl:Thing wikidata:Q12136 yago:WikicatVascular-relatedCutaneousConditions yago:Abstraction100002137 yago:Attribute100024264 yago:Condition113920835 dbo:Disease yago:State100024720 |
| rdfs:comment |
Blueberry muffin baby, also known as extramedullary hematopoiesis, describes a newborn baby with multiple purpura, associated with several non-cancerous and cancerous conditions in which extra blood is produced in the skin. The bumps range from 1-7mm, do not blanche and have a tendency to occur on the head, neck and trunk. They often fade by 3 to 6 weeks after birth, leaving brownish marks. When due to a cancer, the bumps tend to be fewer, firmer and larger. (en) |
| rdfs:label |
Blueberry muffin baby (en) |
| owl:sameAs |
freebase:Blueberry muffin baby yago-res:Blueberry muffin baby wikidata:Blueberry muffin baby dbpedia-fa:Blueberry muffin baby http://ml.dbpedia.org/resource/ബ്ലൂബെറി_മഫിൻ_ശിശു https://global.dbpedia.org/id/LN8z |
| prov:wasDerivedFrom |
wikipedia-en:Blueberry_muffin_baby?oldid=1116115126&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Blueberry_muffin_baby.jpg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Blueberry_muffin_baby |
| is dbo:wikiPageDisambiguates of |
dbr:Blueberry_muffin |
| is dbo:wikiPageRedirects of |
dbr:Blueberry-muffin_baby dbr:Blueberry_muffin_rash |
| is dbo:wikiPageWikiLink of |
dbr:Rubella dbr:Congenital_rubella_syndrome dbr:Blueberry_muffin dbr:Aagenaes_syndrome dbr:List_of_skin_conditions dbr:Strawberry_cervix dbr:Blueberry-muffin_baby dbr:Blueberry_muffin_rash |
| is foaf:primaryTopic of |
wikipedia-en:Blueberry_muffin_baby |
