CPA3 (original) (raw)
Carboxypeptidase A3 (mast cell carboxypeptidase A), also known as CPA3, is an enzyme which in humans is encoded by the CPA3 gene. The "CPA3" gene expression has only been detected in mast cells and mast-cell-like lines, and CPA3 is located in secretory granules. CPA3 is one of 8-9 members of the A/B subfamily that includes the well-studied pancreatic enzymes carboxypeptidase A1 (CPA1), carboxypeptidase A2 (CPA2), and carboxypeptidase B. This subfamily includes 6 carboxypeptidase A-like enzymes, numbered 1-6. The enzyme now called CPA3 was originally named mast cell carboxypeptidase A, and another protein was initially called CPA3. A gene nomenclature committee renamed mast cell carboxypeptidase A as CPA3, and the original CPA3 reported by Huang et al. became CPA4 to reflect the order of th
| Property | Value |
|---|---|
| dbo:abstract | Carboxypeptidase A3 (mast cell carboxypeptidase A), also known as CPA3, is an enzyme which in humans is encoded by the CPA3 gene. The "CPA3" gene expression has only been detected in mast cells and mast-cell-like lines, and CPA3 is located in secretory granules. CPA3 is one of 8-9 members of the A/B subfamily that includes the well-studied pancreatic enzymes carboxypeptidase A1 (CPA1), carboxypeptidase A2 (CPA2), and carboxypeptidase B. This subfamily includes 6 carboxypeptidase A-like enzymes, numbered 1-6. The enzyme now called CPA3 was originally named mast cell carboxypeptidase A, and another protein was initially called CPA3. A gene nomenclature committee renamed mast cell carboxypeptidase A as CPA3, and the original CPA3 reported by Huang et al. became CPA4 to reflect the order of their discovery. (en) CPA3 (англ. Carboxypeptidase A3) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 3-ї хромосоми. Довжина поліпептидного ланцюга білка становить 417 амінокислот, а молекулярна маса — 48 670. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Кодований геном білок за функціями належить до гідролаз, протеаз, , . Задіяний у такому біологічному процесі як поліморфізм. Білок має сайт для зв'язування з іонами металів, іоном цинку. Локалізований у цитоплазматичних везикулах. (uk) |
| dbo:wikiPageID | 15068356 (xsd:integer) |
| dbo:wikiPageLength | 13468 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1053697160 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Endopeptidase dbr:Endothelin_1 dbr:C-terminal dbr:Biopsies dbr:Apolipoprotein_B dbr:Degranulation dbr:Anaphylaxis dbr:Mast_cells dbr:Gene dbr:Mucosa dbr:Potato_carboxypeptidase_inhibitor dbr:Aliphatic dbr:Amino_acid dbr:Exons dbr:Angiotensin dbr:Carboxypeptidase_B dbr:Chromosome_3 dbr:Chymase dbr:Heparin dbr:Aromatic dbr:LDL dbr:Ascaris dbr:Autoimmune_disease dbr:Nematode dbr:Neurotensin dbr:Sepsis dbr:Mast_cell dbr:Tryptase dbr:N-terminal dbr:CPA1 dbr:CPA2 dbr:SR48692 dbr:Tissue_carboxypeptidase_inhibitor |
| dbp:wikiPageUsesTemplate | dbt:Cite_journal dbt:Infobox_gene dbt:Refbegin dbt:Refend dbt:Reflist dbt:UCSC_gene_info |
| gold:hypernym | dbr:Enzyme |
| rdf:type | owl:Thing dbo:Biomolecule dbo:Gene wikidata:Q206229 wikidata:Q7187 dbo:HumanGene dbo:Protein |
| rdfs:comment | Carboxypeptidase A3 (mast cell carboxypeptidase A), also known as CPA3, is an enzyme which in humans is encoded by the CPA3 gene. The "CPA3" gene expression has only been detected in mast cells and mast-cell-like lines, and CPA3 is located in secretory granules. CPA3 is one of 8-9 members of the A/B subfamily that includes the well-studied pancreatic enzymes carboxypeptidase A1 (CPA1), carboxypeptidase A2 (CPA2), and carboxypeptidase B. This subfamily includes 6 carboxypeptidase A-like enzymes, numbered 1-6. The enzyme now called CPA3 was originally named mast cell carboxypeptidase A, and another protein was initially called CPA3. A gene nomenclature committee renamed mast cell carboxypeptidase A as CPA3, and the original CPA3 reported by Huang et al. became CPA4 to reflect the order of th (en) CPA3 (англ. Carboxypeptidase A3) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 3-ї хромосоми. Довжина поліпептидного ланцюга білка становить 417 амінокислот, а молекулярна маса — 48 670. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk) |
| rdfs:label | CPA3 (en) CPA3 (uk) |
| owl:sameAs | freebase:CPA3 wikidata:CPA3 http://tt.dbpedia.org/resource/CPA3 dbpedia-uk:CPA3 https://global.dbpedia.org/id/kAdj |
| prov:wasDerivedFrom | wikipedia-en:CPA3?oldid=1053697160&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:CPA3 |
| is dbo:wikiPageRedirects of | dbr:CPA3_(gene) |
| is dbo:wikiPageWikiLink of | dbr:List_of_human_protein-coding_genes_1 dbr:Zinc_carboxypeptidase dbr:Carboxypeptidase_A dbr:CPA3_(gene) |
| is foaf:primaryTopic of | wikipedia-en:CPA3 |