Geniposide (original) (raw)

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Geniposide, the glycoside form of genipin, is a bioactive iridoid glycoside that is found in a wide variety of medicinal herbs, such as Gardenia jasminoides (fruits) .Geniposide shows several pharmacological effects (in vitro and in vivo) including neuroprotective, antidiabetic, hepatoprotective, anti-inflammatory, analgesic, antidepressant-like, cardioprotective, antioxidant, immune-regulatory, antithrombotic and antitumoral activity.These pharmacology benefits arise through the modulating action of geniposide on several proteins and genes that are associated with inflammatory and oxidative stress processes.

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dbo:abstract Geniposide, the glycoside form of genipin, is a bioactive iridoid glycoside that is found in a wide variety of medicinal herbs, such as Gardenia jasminoides (fruits) .Geniposide shows several pharmacological effects (in vitro and in vivo) including neuroprotective, antidiabetic, hepatoprotective, anti-inflammatory, analgesic, antidepressant-like, cardioprotective, antioxidant, immune-regulatory, antithrombotic and antitumoral activity.These pharmacology benefits arise through the modulating action of geniposide on several proteins and genes that are associated with inflammatory and oxidative stress processes. (en)
dbo:alternativeName Jasminoidin; methyl 1-(hexopyranosyloxy)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (en)
dbo:iupacName Methyl (1S,4aS,7aS)-7-(hydroxymethyl)-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (en)
dbo:thumbnail wiki-commons:Special:FilePath/Geniposide_structure.svg?width=300
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dbo:wikiPageWikiLink dbc:Monoterpenes dbr:Cortisol dbr:Creatinine dbr:Amyloid_plaques dbr:Genipin dbr:Corticotropin-releasing_hormone dbr:Phosphoinositide_3-kinases dbr:Malondialdehyde dbc:Pyrans dbr:Heme_oxygenase dbc:Glucosides dbr:Gardenia_jasminoides dbr:5-Hydroxyindoleacetic_acid dbr:Fluoxetine dbr:Glucagon-like_peptide-1 dbr:Glucuronide dbr:Glycogen_phosphorylase dbr:Glycoside dbr:Hippocampus dbr:Jaundice dbr:Taurine dbr:Synapses dbr:Reactive_oxygen_species dbr:Gut-associated_lymphoid_tissue dbr:NFE2L2 dbr:Phosphorylation dbr:Interleukin-4 dbr:Striatum dbr:P38_mitogen-activated_protein_kinases dbr:Superoxide_dismutase dbr:Iridoid_glycoside dbr:Urea_nitrogen dbr:Serotonergic_system dbr:Aspartate_aminotransferase dbr:Hydroxyl_groups dbr:Alanine_aminotransferase dbr:5-hydroxytryptamine dbr:Adrenocorticotropic dbr:Glucose-6-phosphatase dbr:NAD(P)H_dehydrogenase dbr:Interleukin-2 dbr:TGF-beta_1 dbr:File:Geniposide_structure.svg dbr:JNK-mitogen-activated_protein_kinases
dbp:imagefile 200 (xsd:integer)
dbp:imagename Skeletal formula of Geniposide (en)
dbp:othernames Jasminoidin; methyl 1--7--1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (en)
dbp:pin Methyl -7--1-{[-3,4,5-trihydroxy-6-oxan-2-yl]oxy}-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (en)
dbp:verifiedfields changed (en)
dbp:watchedfields changed (en)
dbp:wikiPageUsesTemplate dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Ebicite dbt:Fdacite dbt:GHS06 dbt:H-phrases dbt:Keggcite dbt:P-phrases
dcterms:subject dbc:Monoterpenes dbc:Pyrans dbc:Glucosides
rdf:type owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound
rdfs:comment Geniposide, the glycoside form of genipin, is a bioactive iridoid glycoside that is found in a wide variety of medicinal herbs, such as Gardenia jasminoides (fruits) .Geniposide shows several pharmacological effects (in vitro and in vivo) including neuroprotective, antidiabetic, hepatoprotective, anti-inflammatory, analgesic, antidepressant-like, cardioprotective, antioxidant, immune-regulatory, antithrombotic and antitumoral activity.These pharmacology benefits arise through the modulating action of geniposide on several proteins and genes that are associated with inflammatory and oxidative stress processes. (en)
rdfs:label Geniposide (en)
owl:sameAs wikidata:Geniposide https://global.dbpedia.org/id/2XudD
prov:wasDerivedFrom wikipedia-en:Geniposide?oldid=1122121358&ns=0
foaf:depiction wiki-commons:Special:FilePath/Geniposide_structure.svg
foaf:isPrimaryTopicOf wikipedia-en:Geniposide
is dbo:wikiPageWikiLink of dbr:Saffron dbr:Genipin
is foaf:primaryTopic of wikipedia-en:Geniposide